Sentences with phrase «wide association study results»

Another way of looking at genome - wide association study results is the so called pathway - based approach, which links SNPs considered mutually involved in a pathway.

Not exact matches

Only 1 case - control study from the Netherlands has reported results.262 This study did not find an association between usual digit - sucking (reported as «thumb - sucking») and SIDS risk (OR: 1.38 [95 % CI: 0.35 — 1.51]-RRB-, but the wide CI suggests that there was insufficient power to detect a significant association.

The basis for this project was the GWAS Catalog, where the results of all published genome - wide association studies are recorded.

And he says that the genome - wide studies that failed to reproduce his results lacked sufficient power to reveal the association between TOMM40 and Alzheimer's disease.

The software allowed them to compare the results of the more than 1,400 genome - wide association studies (GWAS) that have been published on the topic so far.

The results were confirmed in a genome - wide association study and replicated in 1,745 patients in four independent cohorts of patients with IBS and control subjects.

Their analysis also considered results from two earlier genome - wide association studies and confirmed certain previous findings.

The researchers integrated these data with results from a prior Psychiatric Genomic Consortium genome - wide - association study, based on clinician - vetted diagnoses of more than 20,000 patients and controls of European ancestry.

By examining the results of genome - wide association studies (GWAS) in conjunction with experiments on mouse and human red blood cells (RBCs), researchers in the lab of Whitehead Institute Founding Member Harvey Lodish have identified the protein cyclin D3 as regulating the number of cell divisions RBC progenitors undergo, which ultimately affects the resulting size and quantity of RBCs.

Here, we present a large (n = 107,207) genome - wide association study (GWAS) of general cognitive ability («g»), further enhanced by combining results with a large - scale GWAS of educational attainment.

The results of this study suggest that high - resolution fine - mapping in large samples can convert many discoveries from genome - wide association studies into statistically convincing causal variants, providing a powerful substrate for experimental elucidation of disease mechanisms.

Using individual - level data from 335,464 participants in the UK Biobank and summary association results from seven large - scale genome wide association studies, we examined the effect of this nitric oxide signaling score on cardiometabolic and other diseases.

The Michigan Association of School Administrators released results from a State - wide study last month by the School Finance Research Collaborative examining school funding in Michigan that could change.

Biopsy results from the affected puppy were sent to the University of California, San Diego - Comparative Neuromuscular Laboratory where an inflammatory and necrotizing myopathy of undetermined origin was concluded and a GWAS study (genome - wide association study) was recommended on their report of March 7, 2016.

These non-significant results are arguably due to the study's relatively small sample size for a genome - wide association study that requires multiple testing (ranging from N = 372 — 436 in the high and low trait comparison groups), making it unclear whether the same genetic variants are involved in these sub-domains.

The results of the present study suggest that the debate about the validity of cG × E (Duncan and Keller, 2011) and the preferred strategy of genome - wide association studies, rather than studies of candidate genes, merits nuance, as these designs are complementary.