Sentences with phrase «wide profiling of»

Performs genome - wide profiling of vector integration sites as readout of cell growth at clonal level, in basic research studies and technology development, in preclinical safety studies and in gene therapy treated patients.

Interestingly, they will also use genome - wide profiling of the cells» transcription profile — the genes that have been transcribed to messenger RNA — to see what pathways are activated in the cells after EDN insult.

Digenome - seq: genome - wide profiling of CRISPR - Cas9 off - target effects in human cells.

GUIDE - seq enables genome - wide profiling of off - target cleavage by CRISPR - Cas nucleases.

The icing in the cake of course are the features of most online dating sites, such as the easy access to the wide profiles of people, with their photos, audio and video clips available at an instant.

Not exact matches

Empty shopfronts in some of Perth's high - profile retail strips are a sign of WA's wider economic malaise.

Indeed, even his newly elevated profile won't entirely dispel the challenges that bedeviled his failed 2006 bid, namely the Socialist Party's wide swath of voters.

Facebook announced plans Wednesday to shut down its third - party data provider division as part of a wider effort to clean up data practices following a massive leak of user profiles.

The problem is a board and top executive team that don't always appear to have control of its wide - ranging cast of characters, including founders who have attained near - celebrity status (another co-founder, Biz Stone, is a regular on NPR, and earlier this year Dorsey was profiled in Vanity Fair), headstrong and divisive managers, and investors used to getting their way.

Operation Pawn Storm is an active economic and political cyber-espionage operation that targets a wide range of high - profile entities, from government institutions to media personalities.

The flexibility of having lower down payment requirements, tolerance for a wider range of credit histories and the potential for easier future refinancing makes FHA loans a better match for buyers that may not have the right financial profile for other types of home loans.

These credit - reporting agencies also offer a wider array of business credit services [3], like public records of critical business information such as liens and judgments, as well as corporate profiles for high - risk credit decisions.

As I've frequently observed, the strongest expected market return / risk profile is associated with a material retreat in valuations that is then joined by an early improvement across a wide range of market internals.

Oil prices spiked to a two - year high after Saudi Arabia launched a country - wide probe into corruption, detaining numerous high - profile individuals, including prominent businessmen and members of the ruling al - Saud family, as well as current and former ministers.

While other loans may offer options similar flexibility on down payments, FHA loans allow for a wider range of income profiles and debt ratios.

Thanks to long - standing relationships with our sponsorship partners you'll have access to a wide range of high - profile events.

I personally liked how the author profiles a wide variety of successful real estate investors (from 20 something to 50 - year - old single moms) who all started small and built massive wealth from their real estate portfolios.

BASF's award - winning omega - 3s» sensory profile allows the ingredients to be easily formulated in a wide variety of foods and beverages.

Turkey is such a versatile protein, that you can be sure to showcase a wide variety of tastes and flavour profiles.

«With improved taste and nutrition profiles, gluten - free foods are now appealing to an even wider audience, and in fact, snacks are the largest and fastest growing gluten - free food segment,» said Rod Troni, Chief Marketing Officer, Snyder's - Lance, Inc. «That's why Snyder's - Lance is committed to offering more gluten - free options to consumers who desire them because of a gluten sensitivity or just because they deem them healthier.

Our FlavorLab is a hot - bed of innovation, where highly experienced specialists create proprietary enhancing and masking flavors to suit a wide variety of categories, ranging from beverage to dairy to baked goods to savory — all while delivering the natural taste profiles that consumers want.

Although the sauces in this club are not very hot, they include a wide variety of flavor profiles from tangy Louisiana - style to smoky Chipotle to sweet fruit - based.

Our proprietary and patent - protected technologies, our unrivaled expertise in capsule polymer science, and our product and process design capabilities help our customers meet their target product profiles and commercial objectives, while allowing rapid development across a wide range of dosage forms.

«Arturo is a dynamic and creative professional who has prepared world - class cuisine for a wide range of discriminating, high - profile and VIP guests,» said Kipping.

«Redd offers a huge range of powerful ingredients, including 11 superfoods that provide a wide array of potent nutrients and bold flavor profiles including chia seed, acai, goji berries, mangosteen, maca and quinoa.

If Spurs were to actually win a major trophy or two, with the increased profile and advertising revenue that would bring to the club, plus increased gate receipts, the current small gap between the performance of the two clubs on the field might become wider.

The 2017 NBA offseason was completely bonkers, owing to a couple of blockbuster trades, a few high - profile free agents, and a league - wide allergic reaction to the Warriors» dominance.

However the most high - profile target Ancelotti will pursue is undoubtedly Tottenham wide - man Gareth Bale, who has been linked with interest from Real Madrid for the best part of a year.

Firmino can play in a number of roles from out wide in a central midfield role as well as up front and the Figueirense player may feel a high profile move to Liverpool could aid his push for a first Brazilian national team cap.

NFL.com's profile of him paints him as a player too small to be a full - time running back and too inexperienced to make an immediate impact at wide receiver.

One year of video courses featuring experts on a wide range of small business topics, feedback directly from Jill Salzman and fellow mom entrepreneurs, an accountability buddy, branding and marketing know - how, a profile in the Founding Moms Directory, monthly webinars, and so much more.

Visit CarlyMarie's facebook page for a wide variety of banners, cover and profile images for infant, baby, pregnancy, and child loss.

· Tully's Coffee ® offers 17 different blends in a wide range of flavor profiles, including «Spirited» light roast, «Balanced» medium roast, and «Grand» dark roast collections.

An emerging body of literature in adults has begun to establish clear associations between gut microbiome composition and a wide range of health outcomes.1 - 6 In contrast, comparatively little is known about the gut microbiome in infants and children, the exposures that shape it, and its lifelong health effects.7 Although limited in their size and scope, a number of studies have established associations between intestinal microbiome profiles in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequences.

Opportunities for assessing wider measures of child health from the Early Years Profiles are limited so Northumberland is unusual in having data available for gastroenteritis hospital admissions for two consecutive years.

[ii] There is also strong support from a wide range of high profile groups, including the police and emergency services, road safety charities, insurance firms and health bodies (see notes to editors for the full list of stakeholder supporters).

Mueller appears to be looking at a wide variety of topics — including the high - profile firings of some of the president's advisors.

According to the state, Gutman has «tried and argued appeals in a wide range of complex, high - profile intellectual property cases» and served as lead counsel for companies like Intel, Cisco and Verizon, to name just a few.

He opportunistically making a good deal of the homelessness issue to generate a state - wide profile, which is a somewhat more left - leaning issue, but again there is a good deal of «New Boris» in much of this.

To its credit, it's changed app permissions so that developers can no longer access such a wide network of profiles.

According to documents leaked to Hans — Martin Tillack, a German investigative journalist, and think tank Open Europe, many high - profile MEPs are members of the scheme, including Syed Kamall, Leader of Conservative MEPs; Glenis Willmott, the leader of the European Parliamentary Labour Party; Sir Graham Watson, the president of the EU — wide Alliance of Liberals and Democrats for Europe; and Nigel Farage, leader of Ukip.

The technology for genome - wide profiling using microarrays was newly available, and with it came tremendous excitement, parallel to the mapping of the human genome.

In their investigations or so - called genome - wide association studies, the team of researchers compared the genetic profile of study participants to the forced vital capacity (FVC), a volume parameter of lung function.

Indeed using genome - wide transcriptional profiling, the researchers revealed that expression of clipped H3.3 silences genes that regulate the division and duplication of a cell.

And much wider use should be made of biological profiling — the athlete's «biological passport» — which will show up tiny changes made to the individual's unique genetic blueprint by doping substances and methods, without the need to identify the presence of the substance itself, when regularly monitored.

Essentially, in exchange for a DNA sample and a fee ranging from $ 399 to $ 2,500, clients receive a profile summarizing their risk for a wide range of illnesses and conditions, from back pain to breast cancer.

By better understanding the limitations of genome - wide sequencing, Vogelstein notes, researchers and policymakers might be better able to direct funding and efforts to areas, such as Alzheimer's disease, where a person's genetic profile might have a very real effect on their likelihood of getting the disease.

«Because the primary Small Intestine Chip recapitulates the physical microenvironment that cells experience inside the human body, such as fluid flow and cyclic peristalsis - like stretching motions, it exhibits a genome - wide gene expression profile that comes closer to its in vivo counterpart than that of the same intestinal cells grown as 3D organoids,» said first - author Magdalena Kasendra, Ph.D., a former Postdoctoral Fellow on Ingber's team and now Principal Scientist at Emulate, Inc. in Boston.

The team found that people who were more and less fit had vastly different metabolite profiles across a wide range of exercise durations — from 10 minutes of treadmill running to completion of the Boston Marathon.

Dav Doodnauth, an MD and CEO of LifeLine Labs in Lexington, also uses genome - wide association studies to produce his «Pegasus Profiles.»