Sentences with phrase «wide sequence data»

We identified rare variants with allele frequency up to 1 % in a reference panel of 433 European individuals from modern Finland, Spain, Italy, Netherlands and Denmark, for which genome - wide sequence data are available16, 17,18.

SciLifeLab researchers present genome - wide sequence data from ancient and present - day humans from Greenland, Arctic Canada, Alaska, Aleutian Islands, and Siberia.

However, the NextSeq series ™ NGS generates genome - wide sequence data as «digital data» in the resolution of single nucleotide and has no specificity, discrimination and sensitivity issues.

Researchers map these snippets onto existing genome - wide sequence data to create a listing of the genome's contact points.

In addition to Tsagaratou and González - Avalos, Sini Rautio of Aalto University School of Science, in Aalto, Finland, was a co-second author of the paper, contributing significantly to the bioinformatic analysis of genome - wide sequencing data.

Not exact matches

«XR - seq provides a new type of sequence data, and in this work we've provided for the first time a genome - wide map of excision repair in a bacterium,» said Adebali.

RGC will provide these centers whole exome sequencing and genome - wide association (with phenotype, where applicable) data free - of - charge.

In addition, we analysed sequence data from sixty individuals representing six closely related species from Lake Victoria, and show genome - wide diversifying selection on coding and regulatory variants, some of which were recruited from ancient polymorphisms.

Ongoing T2D research activities at CRGGH include 1) whole - exome sequencing of African families with at least four affected members (data generation is complete and analysis is ongoing), 2) GWAS of 1,200 cases and 1,200 controls from West Africa using the new and more efficient African - centric Affymetrix Axiom genome - wide array with more than 2 million markers, and 3) whole genome expression analysis on skeletal muscle obtained from biopsy from 45 subjects (expression QTL (eQTL) studies on the dataset are complete).

Feng, H., Zhang, X. & Zhang, C. mRIN for direct assessment of genome - wide and gene - specific mRNA integrity from large - scale RNA - sequencing data.

Our supermatrix expands upon these previous studies by bringing together sequences from a wide array of molecular studies, supplemented by new data for four genes, to yield a single primate phylogeny with strong support for the monophyly of most primate genera, families, and higher - level taxa (Primates, Strepsirrhini, Lemuriformes, Lorisiformes, Haplorhini, Tarsiiformes, Simiiformes, Catarrhini, Platyrrhini).

The MRC Centre for Genomics and Global Health (CGGH) is supporting TRAC by leading a genome - wide association study and population genetic analysis that integrates TRAC clinical data with genome sequencing data generated through a partnership with MalariaGEN and the Wellcome Trust Sanger Institute.

Sequencing run data can be run through a wide range of open - source or commercial pipelines developed for Illumina data.

The sequencing work for this project has been done at the Wellcome Trust Sanger Institute, and the next phase of work is to develop a detailed catalogue of variants and a reference panel of quality - controlled genotyping data that can be used for accurate imputation in genome - wide association studies of malaria and other diseases.

«Given the power of such comparisons, there is a growing hunger among biologists and medical researchers for free and publicly available sequence data on a wide variety of organisms.

Microsatellite genotypes were obtained for 203 clinical infection samples from eight locations, and Illumina paired - end sequences were obtained to yield high coverage genome - wide single nucleotide polymorphism (SNP) data for 65 clinical infection samples from four locations.

A genome - wide FST scan comparison with previous sequence data from an area in West Africa with higher infection endemicity indicates that regional gene flow prevents genetic isolation, but revealed allele frequency differentiation at three drug resistance loci and an erythrocyte invasion ligand gene.

On the one hand, the power of rare genetic variants clearly shows the value in whole - genome sequencing of ancient DNA: While SNP capture technology provides a far more economical way to obtain genome - wide data from ancient DNA (ref.

Carr's work with the Common Core State Standards (CCSS) includes working with BOCES organizations and with school and district leaders to build capacity for successful implementation; creating protocols, tools, and templates for district - wide design of scope and sequence documents and units of study tied directly to the CCSS; facilitating summer Leadership Institutes for school teams to plan strategic actions to bring the CCSS and data - driven instruction to routine use in all classrooms; and conducting professional development through interactive keynotes, workshops for teacher leaders, leadership seminars, and individual coaching with school and district administrators.