Sentences with phrase «wide systemic analysis»

Validating this concept, we previously demonstrated that human pluripotent stem cells and derivatives which, express the causal mutation implicated in the Myotonic Dystrophy type 1 (DM1), offer pertinent disease - cell models, applicable for a wide systemic analysis ranging from mechanistic studies to therapeutic screening.

Not exact matches

«Genome - wide analysis allowed us to identify a gene, VNN - 1, whose expression discriminated between good and poor responders to systemic corticosteroid treatment,» said Gurjit Khurana Hershey, MD, PhD, senior author and director of Asthma Research at Cincinnati Children's.

Validating this original concept, we previously demonstrated that PGD - derived hES cells and their derivatives, which express the causal mutation implicated in the Myotonic Dystrophy type 1 (DM1), offer pertinent disease - cell models, applicable for a wide systemic mechanistic analysis ranging from functional studies at the cellular level to a large - scale drug screening.