Sentences with phrase «widely studied drugs»

Not exact matches

On February 24th, the New York - based drug giant announced that Prevenar 13, a drug widely used to prevent infection in children, met its primary endpoint in a post-approval study consisting of 85,000 individuals aged 65 and older.

Carrageenan is such an efficient inflammatory agent and carcinogen, it is widely used with laboratory animals to study the molecular signals involved in cancer and anti-inflammatory drugs.

PFC was one of the initial study sites for FDA approval of the Follistim Pen, an FSH medication delivery device that today has made fertility drug administration much easier and comfortable for patients and is now widely used for ovarian stimulation.

A new study explains how a widely used drug is effective against inflammatory bowel disease and rejection of bone marrow transplants, while suggesting another way to address both health issues.

The drug I studied for my PhD and gave to a human for the first time in 1986 (lamotrigine) is now a widely used anti-epileptic and there are many successful interventions on the market I have been associated with over the years.

In this study, however, he and his collaborators took a different approach: analyzing micro-sized bacteria that hobble a widely - used chemo drug.

In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol - lowering drug increased a precursor of HDL (high - density lipoprotein), the «good cholesterol,» according to new research published in PLOS ONE from the Perelman School of Medicine at the University of Pennsylvania.

«When one considers the modest decrease in risk of adverse outcomes associated with the use of a number of widely used medications such as anti-cholesterol drugs, the effect sizes seen in this study are really impressive,» said Dr. Memtsoudis.

NEW ORLEANS — A long - awaited study on painkillers called nonsteroidal anti-inflammatory drugs, the most widely prescribed class of drugs in the world, has concluded that the three most commonly used carry a similar risk of cardiovascular complications.

The most widely reported involved a study by Cleveland Clinic cardiologist Steven Nissen showing that the diabetes drug Avandia, FDA - approved in 1999, raised the risk of heart attack by 30 to 40 percent.

Many patients and physicians assume that the safety and effectiveness of newly approved drugs is well understood by the federal Food and Drug Administration (FDA)-- but a new study by researchers at Yale School of Medicine shows that the clinical trials used by the FDA to approve new drugs between 2005 and 2012 vary widely in their thoroughness.

In animal and cell culture studies, the drug inhibited growth both in estrogen - dependent breast cancer cells and in cells that had developed resistance to the anti-estrogen tamoxifen and / or to the aromatase inhibitors, two of the most widely used types of drugs to prevent and treat estrogen - dependent breast cancer.

They also included, in the mid-1900s, the powerful psychedelic compound lysergic acid diethylamide, or LSD, that is still being studied and has been widely used as an illegal recreational drug.

Penicillin allergies are widely listed in patient histories, but, a Mayo Clinic study found 80 to 90 percent of patients who listed a penicillin allergy had no real evidence of a true reaction and avoided the drug unnecessarily.

This article cites the widely publicized studies showing that» [r] esearchers at Bayer could not replicate 43 of 67 oncological and cardiovascular findings reported in academic publications,» and» [r] esearchers at Amgen could not reproduce 47 of 53 landmark oncological findings for potential drug targets.»

«Aspirin is a widely used cardiovascular preventive drug and also has an emerging role in cancer treatment and prevention,» said Valerie O'Donnell, Ph.D., Division of Infection and Immunity, Cardiff University, and the study's lead author.

Interferon - a, a drug widely used to treat hepatitis C and several cancers, may also work against SARS, according to a study published online this week by Nature Medicine.

Stimulant drugs are widely prescribed to treat ADHD, which is believed to affect up to 8 percent of U.S. college students, and several studies have documented frequent nonmedical use — either without a prescription or taking higher - than - prescribed doses — particularly among college students.

Researchers have found a way to increase the effectiveness of a widely used cancer drug while decreasing the risk of heart - damaging side effects, according to a new study by researchers from The University of Texas Medical Branch at Galveston and Texas Tech University Health Sciences Center.

Statins are among the most widely used drugs for prevention of cardiovascular disease, but there have been some studies that suggest a link to an antimicrobial effect against S. aureus.

Adverse drug reactions kill tens of thousands of people annually; one widely cited study published in the Journal of the American Medical Association (JAMA) in 1998 puts the number at more than 100,000.

This has been supported by studies showing a rapid response to selective serotonin reuptake inhibitors (SSRIs), a widely used class of antidepressant drugs.

The study, reported online April 28, 2015, in the Journal of General Internal Medicine, confirms past findings on the link between the widely prescribed drugs and diabetes risk.

Mansi stresses that the study doesn't definitively show that statins cause diabetes, nor does it mean people should stop using the drugs, which are widely prescribed to help people lower their cardiac risk factors.

A landmark 2016 Cleveland Clinic study of widely used pain - relieving drugs showed that celecoxib (Celebrex) was associated with comparable cardiovascular safety and better gastrointestinal (GI) and kidney safety when compared...

Looking forward, the researchers are applying their approach to study cellular drug responses in clinical samples, but also aim to make their methods widely accessible.

The chemical reactions she has developed are widely used throughout the pharmaceutical industry to create new drug candidates, are being studied by chemical companies interested in accessing important chemicals used in farming, and are being utilized to prepare a type of chemical (tracer) that allows doctors to view the heart's sympathetic nervous system through positron emission tomography (PET) scans.

Now, in a new study in the journal Cancer Cell, Shaw and a team of scientists at the Salk Institute for Biological Studies found that phenformin, a derivative of the widely - used diabetes drug metformin, decreased the size of lung tumors in mice and increased the animals» survival.

Animal Study Shows Most Widely Prescribed Diabetes Drug Improves Nicotine Withdrawal Symptoms

The availability of a new and improved P. cynomolgi reference genome sequence will enable in - depth studies of this widely used model parasite, including investigations into dormant stages and the selection of new drug targets and vaccine candidates.

In this study, we utilized the scopolamine model to compare J147 to donepezil, the currently most widely used AD drug.

PHILADELPHIA — In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol - lowering drug increased a precursor of HDL (high - density lipoprotein), the «good cholesterol,» according to new research published in PLOS One from the Perelman School of Medicine at the University of Pennsylvania.

The U.S. drug maker released a statement on Monday saying that its Keynote - 010 study, a randomized Phase two - third trial, showed that patients who were taking two different doses of Keytruda (FDA - approved two mg / kg dose and treatment dose of 10 mg / kg given every three weeks) had longer survival compared to those who took docetaxel, the drug widely used for non-small cell lung cancer (NSCLC).

A drug widely used to treat mild Alzheimer's disease appears to provide no benefit to this group of early - stage patients, according to a new study.

The efficacy of methods was not compared in the study, nor were the costs over time of individual drugs calculated, as dosages and prices vary widely.

WEDNESDAY, Nov. 28 (HealthDay News)-- The widely used heart drug digoxin is associated with an increased risk of death in people with the common heart rhythm disorder know as atrial fibrillation, a new study finds.

However, we also reported that the response to this drug varied widely between individuals and the current study tried

Substance abuse Substance abuse by a child's parent or guardian is commonly considered to be responsible for a substantial proportion of child maltreatment reported to the child welfare services.1 Studies examining the prevalence of substance abuse among caregivers who have maltreated their children have found rates ranging from 19 percent2 to 79 percent or higher.3 One widely quoted estimate of the prevalence of substance abuse among care - givers involved in child welfare is 40 to 80 percent.4 An epidemiological study published in the American Journal of Public Health in 1994 found 40 percent of parents who had physically abused their child and 56 percent who had neglected their child met lifetime criteria for an alcohol or drug disorder.5