Sentences with phrase «wild mice immune»

Not exact matches

This study, «Engineered epidermal progenitor cells can correct diet - induced obesity and diabetes,» is the first to show that an engineered skin graft can survive long term in wild - type mice with intact immune systems.

Because wild mice are constantly exposed to germs and other environmental insults, he adds, they carry microbiomes that have evolved to help their hosts cope with these problems, seemingly making the immune system less reactive to harmless microbes and other environmental insults, yet more reactive to other, potentially deadly ones.

To explore these questions Akiko Iwasaki, professor of immunobiology and investigator of the Howard Hughes Medical Institute, and her co-authors observed replication of the Zika virus in the vaginal tissue of control, wild - type mice (genetically unmodified mice) and mice lacking genes that regulate immune system proteins known as type I interferons.

Geneticist Jiří Forejt of the Czech Academy of Sciences» Institute of Molecular Genetics in Prague wasn't looking for it when he caught wild mice and bred them with lab mice to study diversity of immune system genes.

Professor Mark Viney and colleagues from the University of Bristol and the London School of Hygiene & Tropical Medicine studied the immune systems of 460 wild mice taken from 12 sites in the UK and compared them with mice bred in captivity.

A study by Stephen Abolins, Mark Viney and colleagues of the immune ecology of wild house mice — the same species as the lab mouse — shows that their immune state is promoted by individuals» body condition and constrained by their age.

In mouse models, carcinogen - induced tumors that arise in immunodeficient mice, when transplanted to wild - type mice, are usually eliminated by the intact immune system of the new host.

The present findings are derived from studies using CD4KO mice and thus, raise the question as to whether the CD4 + T cell - independent immune mechanisms in CD4 KO mice differ from those involved in corneal allograft rejection in wild - type mice whose CD4 + T cells population have been depleted with monoclonal antibodies.

However, tumors induced in wild - type mice have arisen despite an intact immune system.

Interestingly, when parental d42m1 sarcoma cells were transplanted into wild - type mice, around 20 % of recipients developed «escape» tumors which evaded immune destruction and progressed (escape clones).

The fluorescent labeling permitted the authors to monitor tumor outgrowth in vivo after mixtures were injected into either wild - type or Rag2 - knockout (immune system deficient) mice.

When transplanted into wild - type mice with intact immune systems, these tumors are eliminated, presumably by T - cells.

We have studied the transcriptome, proteome and metabolic flux of Salmonella, and the transcriptome of the host during infection of wild type C57BL / 6 and immune - deficient gp91 - / - phox mice.

The stronger immune system of wild cats can handle bacteria and any other microorganism present in birds or mice.