Sentences with phrase «wild type control»

As shown in Table 1, all four lines exhibited significant increases in muscle weights compared to wild type control mice.

As the mice aged, their motor performance on a rotarod test (which measures how long the mouse can remain on a rotating rod) became impaired and the length of their strides were significantly shorter than the wild type control mice.

The study also found that SNCA mice displayed fragmented nighttime activity patterns compared to wild type controls and appeared to have a reduced overall sleep time.

Pathological hallmarks of AD, including plaques and loss of synaptic markers, are readily apparent at nine months of age in huAPP / PS1 mice along with clear deficits in spatial memory when compared to wild type controls [7, 10, 11, 31].

We investigated the acquisition of peak responding in R6 / 2 mouse model of Huntington's disease and their corresponding wild type controls.

The level of anxiety in APPswePS1ΔE9 mice was increased according to one report [39] whereas in 7 - month - and 12 - month - old mice of the same strain, there was a reduction in anxiety compared to wild type controls [40, 41]-RRB-.

Not exact matches

Several years ago, while creating a genetically engineered mouse that expresses high levels of the mouse HMGA1 gene to investigate its role in leukemia, Resar and her colleagues made the chance finding that the intestines of these animals were much larger and heavier than those of «wild - type» animals (or control mice that were not genetically modified).

To explore these questions Akiko Iwasaki, professor of immunobiology and investigator of the Howard Hughes Medical Institute, and her co-authors observed replication of the Zika virus in the vaginal tissue of control, wild - type mice (genetically unmodified mice) and mice lacking genes that regulate immune system proteins known as type I interferons.

For prevention studies, they injected mouse α - syn synthetic preformed fibrils into wild - type, normal mice, as a control, and then immediately treated the mice with Syn303, one of the MAbs used (or IgG, another type of common antibody, for the control mice).

Treatment of the long - lived InR dwarfs with a juvenile hormone analog restores life expectancy toward that of wild - type controls.

(A) Histology of control diet (CD) and Western diet (WD)- fed wild - type (WT) and FXR knockout (KO) mice of both genders.

Specifically, rod - mediated inner retinal responses to dim light flashes were faster in diseased mice than in their wild - type controls.

Some 6000 wild - type males, as well as controls, were released.

To determine whether ZFN - mediated disruption of cxcr4 indeed protects CD4 + T cells from an in vitro HIV challenge, human CD4 + T cells from three different ccr5 wild type donors were stimulated and transduced with AdX4 - ZFNs or an AdR5 - ZFNs control.

All clones with the wild type Tyr302, including the Envs from the viral innoculum and two Envs from X4 - ZFN mice utilized CXCR4 approximately 1000-fold more efficiently than CCR5 and comparably to the X4 - tropic control TYBE (Figure 6C).

Control studies were performed using cells expressing either wild - type PREX2 or green fluorescent protein (GFP).

C57BL / 6 wild - type mice (The Jackson Laboratory, 000664; n = 8) were used as an additional control for comparison purposes, but were not included in any statistical analyses.

These are high passage wild type parental clones suitable for DNA extraction, control purposes, but not for germline transmission.

Male or female (5 - 6 wks old) wild type and genetically modified mice (as required for individual investigator's protocols) will be fed a high fat high sucrose diet (from Research Diets ranging in fat from 45 - 58 % of calories as fat, 26 - 39 % carbohydrate (sucrose) and 16 % protein or control diets (10 % fat, 73 % carbohydrate, 16.4 % protein or rodent chow) for up to 16 weeks.

The goal of this protocol (written in French) is to describe the steps and quality controls to prepare new stable murine embryonic stem cells lines: ① either from wild type mouse embryos to introduce a mutation by genetic targeting or homologous recombination to get a genetically modified mouse line ② or from genetically modified mouse embryos with two aims:

White background preference was reduced with axotomy of the induced eye (79 % ± 6 % to 57 % ± 5 %, p = 0.009) and the age - matched wild - type control (83 % ± 6 % to 50 % ± 2 %, p = 6.1 × 10 − 5; Figure 6C and 6D).

ERGs recorded from eyes wholly derived from induced retinal cells were similar to those recorded from eyes on the unoperated side of the same animals and eyes of stage - matched wild - type controls (Figure 6A and 6B).

Since bsl1 - 1 mutants are morphologically comparable to the wild type at ∼ 16 DAS, they were sown a day earlier in a controlled high - light growth chamber and collected alongside the wild type.

We observed similar percentages in wild - type retinas, which contain 18.6 % and 0.12 % BrdU - labeled peripheral and central cells, respectively (2,672 cells counted in ten control retinas).

Interestingly, panicle length was significantly longer in bsl1 - 2 compared with the wild - type control (Figure 1B); however, bsl1 - 2 displayed weaker phenotypes for all other traits evaluated (Supplemental Table 1).

Homologs of well - characterized BR biosynthesis genes were significantly upregulated in bsl1 - 1 mutants compared with wild - type controls (Figure 6; Supplemental Table 2).

To gain insight into how genes and pathways were perturbed at the molecular level with loss of bsl1 function, we used RNA - seq to profile transcriptional differences in bsl1 - 1 inflorescence primordia compared with wild - type controls.

As a control, irradiation of wild - type mice resulted in 100 % mortality after a period of 9 months after irradiation, when the mice were 11 months old (Fig. 3 ⇓ shows the survival curve of the females alone for the purpose of simplifying the discussion below); and mortality was mainly attributable to the development of T - cell lymphomas (Table 3) ⇓.

Methods: R6 / 2 CAG 240 (peak training at 11 weeks of age), zQ175 knock in (KI) HET (peak training at 27 weeks of age) and BAC HD (peak training at 48 weeks of age), as well as respective age - matched wild type (WT) control mice, were trained on the peak interval task (20 s interval) in which response rates during unreinforced peak trials were examined.

To use this tool to detect a BRAF gene edit, simply PCR - amplify the BRAF locus from the edited cells (the PCR product should contain the edited BRAF sequence), and PCR - amplify the BRAF locus from control cells (the PCR product should contain the wild - type BRAF sequence).

For the wild - type control, we overexpressed three copies of UAS GFP using the C7 Gal4 driver.

By combining the use of magnetic tweezers with in vivo laser ablation, we locally control physiologically relevant deformations in wild - type Drosophila embryonic tissues.

Progranulin values were generally normalized to the wild - type sedentary control group, except in Figure 4, which included only Grn + / − mice.

Wild - type control goats were produced by normal sexual reproduction.

We amplified cDNA from wild - type and mutant ovaries (and genomic DNA as a control) using primers located in the exons flanking the mutation.

Wild - type littermates were used as controls for Grn + / − and Grn − / − mice.

(A) BaF3 cells control or stably transduced with wild - type or with V617F, Y931C or V617F / Y931C mutant were washed 3 times in PBS to remove the residual IL - 3 and seeded in 6 - well plates at a concentration of 100,000 cells / mL in culture medium.

The Δhsp70 - x IE were also more rigid than wild - type controls indicating changes in the way the parasites modified their host erythrocyte.

The present study was aimed at identifying behavioral tests that are most sensitive to the emergence of behavioral / neurological deficits in male and female SOD1 G93A mice (SOD - 1) compared to wild - type (WT) controls.

The pGL3 luciferase reporter plasmids with the wild - type or mutated 3 ′ UTR of APC were transiently transfected into HEK293T cells along with 25 nM miR - 142 precursor or negative control precursor.

However, TPH2 − / − mice were not different from wild - type controls on any of these tests and in some cases were more resistant to the development of depression - like behaviors than wild - type controls.»

If the cat is an untagged stray or feral (wild cat), trap it with a live trap (the raccoon - type trap) then turn it over to the Osceola County Animal Control Office on Kissimmee Park Road in St. Cloud or a local Humane Society.

All dogs with AHE were homozygous for this mutation, 15/41 healthy AH control dogs were heterozygous carriers while 26/41 normal healthy AH dogs were wild type.

For immunohistochemical localization of motor end - plates, serial cryosections (8 µm) were obtained from the external intercostal muscle of 1 affected Labrador Retriever, archived frozen muscle of a previously diagnosed Jack Russell Terrier with CMS due to AChR deficiency (neuromuscular disease control), and a normal dog (wild - type control).

Further customisation comes in the form of adjusting the time of day and weather conditions, A.I. difficulty, race length for certain event types such as wild rush and driving assists including multiple elements of brake assistance, traction control system, steering stability, semi-automatic or manual gear shifting, racing line indicators throughout the entire track, only through the corners or not at all and cosmetic or mechanical damage modelling to your ideal preferences.

You can play the most animal here, as well as animal jam, animal sounds, animal shelter, animals, animal control, animal crossing pocket camp, animal house, animal crossing, animal cell, animal hospital, animal kingdom, / g / 11cjk43sfk, American drama series, Animal Kingdom, eJzj4tVP1zc0TM7KNjEuTssGABsaBCI, / m / 02hzwl, Disney's Animal Kingdom, Theme park in Bay Lake, Florida, Disney's Animal Kingdom, eJzj4tTP1TcwyqgqzwEADa0DBg, Disney's Animal Kingdom, animal games online, wild animals games, zoo animals games, animal vet games, animal games for kids, animals games free download, fun animal games, virtual animal games and many more types of animal.