Sentences with phrase «wild type donors»

In the absence of HIV infection, the cxcr4 disruption frequency remained stable over time in four independent experiments testing four different ccr5 wild type donors as measured by deep sequencing.

To determine whether ZFN - mediated disruption of cxcr4 indeed protects CD4 + T cells from an in vitro HIV challenge, human CD4 + T cells from three different ccr5 wild type donors were stimulated and transduced with AdX4 - ZFNs or an AdR5 - ZFNs control.

Not exact matches

He calls the third ingredient the template, or donor DNA: «It's the DNA that encodes the edit you want to make, in this case wild - type HBB.»

For experiments requiring complete eye field replacement (A and B), one half of the eye field was surgically removed from wild - type, stage 15 (host) embryos, and replaced with the donor cells from one half of an explant.