Sentences with phrase «wild type mice»

«Early during pregnancy, if the mother is infected, there is significant impact on the fetus, even in wild type mice,» she noted.
Investigators at the National Institute on Aging compared wild type mice with specially bred mice that were transgenic for the A53T mutation of the human α - synuclein (SNCA) gene under the control of a human thymus cell antigen 1, theta (THY - 1) promoter.
Mstn − / − mice carrying a follistatin transgene had about four times the muscle mass of wild type mice, demonstrating the existence of other regulators of muscle mass with similar activity to myostatin.
Liliana M.; El - Khodor B F.; Hornberger M.; Park, Larry; Howland, David; Brunner D. Effect of the rd1 mutation on motor performance in R6 / 2 and wild type mice [Internet].
«What we found was, if we block mGluR5, which is the glutamate receptor we're interested in, the mice become hyper locomotive so they become able to move better than wild type mice suggesting glutamate receptors might be a good target for treating movement disorders such as Parkinson's disease.
(Left) Blood smears from anemic mice indicate irregular shapes of red blood cells; (right) wild type mice indicate normal shapes of red blood cells.
Both obese humans and mice have significantly elevated soluble Fabp4 / aP2 levels, and injection of recombinant Fabp4 / aP2 into lean wild type mice stimulates hepatic glucose production and gluconeogenesis.
No significant differences in bone growth were seen in wild type mice that received rosuvastatin or vehicle (right and second from right).
Menalled L, El - Khodor B.F, Hornberger M, Park Lm Howland Dm Brunner D. Effect of the rd1 mutation on motor performance in R6 / 2 and wild type mice [Internet].
Gray bars represent muscles from wild type mice, and red bars represent muscles from Mstn − / −, F66, and F66 / Mstn − / − mice.
In neurons of DIXDC1 mutant mice (center) the dendrites — neural antennae that receive input from other brain cells — have fewer of the dendritic spines (white with red arrows)-- the receiving half of most synaptic inputs — compared to dendrites in wild type mice (left).
Moreover, the rank order of magnitude of these increases correlated with the rank order of expression levels of the transgene; in the highest - expressing line, Z116A, muscle weights were increased by 57 — 81 % in females and 87 — 116 % in males compared to wild type mice.
The most dramatic effects were observed in F66 / Mstn − / − mice obtained from crosses with Mstn − / − females, in which muscle weights were approximately quadrupled compared to wild type mice.
As shown in Table 2 and Figure 2c, total fiber number and mean fiber diameter were increased by about 48 % and 19 %, respectively, in Mstn − / − mice compared to wild type mice.
In the most extreme case, muscle weights in F66 / Mstn − / − mice were increased by 250 — 350 % from those seen in wild type mice (Figures 2b and 3).
Numbers represent percent increases relative to wild type mice and were calculated from the data shown in Table 1.
Menalled, L., El - Khodor, B. F., Hornberger, M., Park, L., Howland, D., and Brunner, D. Effect of the rd1 mutation on motor performance in R6 / 2 and wild type mice, in PLoS Currents Huntington Disease..
Menalled L, El - Khodor BF, Hornberger M, Park L, Howland D, Brunner, D.Effect of the rd1 mutation on motor performance in R6 / 2 and wild type mice.
Wild type mice, such as the C57BL / 6 mouse, are relatively resistant to atherosclerosis, but have the capacity to develop mild atherosclerosis under certain conditions.
A very neat paper shows that transgenic mice made to overexpress a certain hormone live much longer than wild type mice: The starvation hormone, fibroblast growth factor - 21, extends lifespan in mice.
a b c d e f g h i j k l m n o p q r s t u v w x y z