«What we found was, if we block mGluR5, which is the glutamate receptor we're interested in, the mice become hyper locomotive so they become able to move better than
wild type mice suggesting glutamate receptors might be a good target for treating movement disorders such as Parkinson's disease.
Not exact matches
Topical application of capsaicin on the dorsal skin of 7,12 - dimetylbenz (a) anthracene — initiated and TPA - promoted TRPV1
wild -
type (WT) and TRPV1 knockout (KO)
mice induced more and larger skin tumors in TRPV1 / KO
mice,
suggesting a TRPV1 - independent mechanism.
In addition, blood estrogen levels at late stages of pregnancy were found to be about two times higher in Nrk mutant
mice than in
wild -
type mice,
suggesting that Nrk is also involved in the regulation of synthesis or secretion of estrogen.
Membrane resistance and rheobase in both dSPN and iSPNs from 2 - month old Q175
mice did not significantly differ from
Wild -
type (WT) dSPN and iSPNs respectively,
suggesting that deficits in SPN excitability emerged largely in parallel in each subtype.
«What this might
suggest is that transfer of some of the «good» microbiota from
wild -
type mice to replace the «bad» microbiota from
mice lacking AIM2 offers increased protection against colorectal cancer,» Man said.