Weston et al. [13] previously identified a major locus affecting the interspecies male
wing size difference, called wing - size - 1 (ws1).
We isolated a locus that contributes substantially to
this wing size difference by increasing cell size and cell number.
Surprisingly, we found that the determinant for
this wing size difference is located in the non-coding region between two known transcription factors, the master sex determining gene doublesex and neurogenesis regulator prospero.
Here, we investigate the recent evolution of sex - specific
wing size differences between two species that involve changes to cell size and number regulation.