There have already been a number of pet parents that have seen wonderful results
with Apoquel, and I expect that it will help a lot more dogs now that it is going to be widely available.
Thanks for sharing your personal experience
with Apoquel, M.K.!
In a clinical trial of dogs with atopic dermatitis, treatment success for pruritus occurred in a significantly greater percentage of the dogs treated
with APOQUEL (66 percent) vs. (4 percent) of dogs treated with placebo (p < 0.0001).
In a trial of dogs with allergic dermatitis, treatment success, as defined by owner - assessed decrease in pruritus, occurred in 67 percent of dogs treated
with APOQUEL vs. 29 percent of dogs treated with placebo after one week of treatment.
The most common side effects observed in dogs treated
with APOQUEL were vomiting (2.3 % in APOQUEL - treated dogs compared to 1.8 % in placebo treated dogs) and diarrhea (2.3 % in APOQUEL - treated dogs compared to 0.9 % in placebo treated dogs).
With APOQUEL, veterinarians now have a first - in - class treatment choice that targets the itch of allergic skin conditions at its source.
In a trial of dogs with atopic dermatitis, dogs treated
with APOQUEL experienced a significant and long - term reduction in itch and inflammation at day 28 of the study.
Treatment
with Apoquel consists of administering two doses per day for up to 14 days.
«Pet owners who complained that their dogs would wake them up in the middle of the night due to intense itch have told me that after treatment
with APOQUEL, the household can sleep more peacefully,» Dr. Lewis said.
These occurred in only a small percentage of dogs treated
with APOQUEL.
You can continue to treat your dog
with APOQUEL for as long as your veterinarian recommends.
Not exact matches
«A Blinded Randomized Placebo - controlled Trial of the Efficacy and Safety of the Janus Kinase Inhibitor Oclacitinib (
Apoquel ®) in Client - owned Dogs with Atopic Dermatitis» was designed in support of a new drug registration to evaluate the safety and efficacy of A
Apoquel ®) in Client - owned Dogs
with Atopic Dermatitis» was designed in support of a new drug registration to evaluate the safety and efficacy of
APOQUELAPOQUEL.
APOQUEL is a targeted new approach to rapidly and safely stop the cycle of itch and inflammation associated
with allergic skin disease in dogs.
APOQUEL is the only animal health product approved for both the control of pruritus associated
with allergic dermatitis and the control of atopic dermatitis in dogs over 12 months of age.
Apoquel (Oclacitinib) may interact
with cyclosporine, glucocorticoids, steroids, and other agents that suppress the immune system of dogs.
APOQUEL ® should not be used in dogs less than 12 months of age or in dogs
with serious infections.
However, because of the many adverse reactions associated
with steroid use, this makes
Apoquel a safer bet.
Recent advancements have been made in the area of antipruritic medications for animals and there are now effective medications
with fewer long term side effects such as cyclosporine (Atopica) and oclacitinib (
Apoquel).
A blinded, randomized, placebo - controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (
Apoquel ®) in client - owned dogs
with atopic dermatitis.
Yes,
APOQUEL is safe to be used
with other treatments such as vaccines, nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, and other allergy medications.4 The use of
APOQUEL has not been evaluated in combination
with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents.
APOQUEL is safe
with minimal side effects.
APOQUEL is prescribed by your veterinarian to control itch and stop inflammation associated
with allergic or atopic dermatitis in dogs 12 months and older.
«Many people think they have higher effectiveness, but they are commonly using them along
with steroids, antihistamines, or other immunosuppressive drugs (cyclosporine,
Apoquel), so the food probably is not as effective as they might believe.»
Gonzales AJ, Bowman JW, Fici GJ, Zhang M, Mann DW, Mitton - Fry M. Oclacitinib (
APOQUEL ®) is a novel Janus kinase inhibitor
with activity against cytokines involved in allergy.
We are sorry to announce that due to a pharmaceutical backorder, The Drake Center is experiencing a shortage of
Apoquel, a new medication recently released on the veterinary market to relieve itching in dogs
with allergic skin disease.
A masked, multisite, well - controlled study of 436 dogs conducted at 26 veterinary clinics in the US evaluated the effectiveness and safety of
APOQUEL, dosed orally twice daily (BID) at 0.4 to 0.6 mg / kg for the control of pruritus associated
with allergic dermatitis, including flea allergy, food allergy, contact allergy and atopic dermatitis
APOQUEL provides relief of both allergic and atopic dermatitis (an inflammatory skin disease associated
with allergies to pollens, molds, and dust mites).
In a trial of dogs
with allergic dermatitis,
APOQUEL produced rapid onset of efficacy within 24 hours.
APOQUEL has not been evaluated in combination
with systemic immunosuppressive agents such as glucocorticoids or cyclosporine.
In addition,
Apoquel can be used for both acute and chronic conditions, which is especially wonderful for those dogs needing long - term itch control
with minimal side effects.
Florham Park, N.J. — August 13, 2013 — Results of a new pivotal study show that
APOQUEL ® (oclacitinib tablet) provides effective and safe control of pruritus associated
with allergic dermatitis in dogs
with a rapid onset of efficacy within 24 hours and without the commonly reported side effects of steroids.
Newer medications such as
Apoquel and Atopica are effective
with less side effects but are expensive to take, especially for life.
APOQUEL is proven to effectively reduce itch within 24 hours and provide long - term relief
with minimal side effects.
APOQUEL produced rapid onset of efficacy within 24 hours - within the first day of treatment, pruritus scores were reduced by at least 2 cm on a 10 cm VAS scale in 44 % of the
APOQUEL - treated dogs compared
with 19 % of the placebo - treated dogs.
About the Study The study, «Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs
with canine allergic dermatitis,» was conducted as a double - masked, placebo - controlled clinical trial aimed to evaluate the safety and efficacy of
APOQUEL compared
with placebo.
APOQUEL is the only animal health product approved for the control of pruritus associated
with allergic dermatitis and the control of atopic dermatitis in dogs over 12 months of age.
While they are currently under control
with a grain free salmon based food and sprays for his feet (grass allergies), at any point he could require cytopoint injections or
apoquel.
«The approval of
APOQUEL is encouraging because it will provide both veterinarians and pet owners
with a treatment that reduces itch within hours and provides long term relief of itching and inflammation for dogs without the side effects of steroids.»
APOQUEL has been used safely
with many common medications including parasiticides, antibiotics and vaccines.
The use of
Apoquel has not been evaluated in combination
with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents.
IMPORTANT SAFETY INFORMATION: Do not use
APOQUEL in dogs less than 12 months of age or those
with serious infections.
«Efficacy and safety of oclacitinib (
APOQUEL) compared to prednisolone for the control of pruritus and clinical signs associated
with allergic dermatitis in client - owned dogs»
Jennifer Schissler Pendergraft, DVM, MS, DACVD, and co-investigator Andrew Simpson, DVM, of Colorado State University James L. Voss Veterinary Teaching Hospital, will receive a grant for their project, «Frequency of urinary tract infection in dogs treated
with oclacitinib (
APOQUEL) for cutaneous hypersensitivity: a prospective study.»
Zoetis cautions that
Apoquel should not be used in dogs less than twelve months of age or in dogs
with serious infections.
Apoquel may be used as part of a multimodal treatment plan which may include flea control and bathing
with medicated shampoos.
If your dog is itchy and you suspect that your dog may have allergies, or if you know that your dog has allergies, schedule a visit
with your veterinarian to discuss whether
Apoquel is a good treatment option for your dog.