The goal is total cholesterol under 160,
with LDL under 100 and HDL above 60.
I was ketogenic for those last 3 labs,
with my LDL - P gradually going from 1580 (high but acceptable) to 2004 (unacceptable).
My doctor is now concerned
with the LDL which reads high.
You might be able to end up
with LDL of 130, TC of 230, HDL of 70 - 80 which would be perfect all around.
It didn't grew from April to now
with LDL around 120 - 130, was maybe a little less.
If I have significant amounts of either or both coconut oil and dairy fat, I tend to have very high total cholesterol (360 +) and high HDL (80 +) coupled
with an LDL of 250 - ish.
I feel good about his HDL and triglycerides and we will work
with the LDL as you suggested.
People who take the highest 80 mg / dl dosage of statins often end up
with LDL levels as low as 40mg / dl, well below even the lowest numbers observed naturally.
My insurance company will be eliminating my «healthy measures» discount
with my LDL at this level... Otherwise, I would probably not be bothered to try.
When it comes to dealing with the risk factors associated with elevated lipoprotein a levels, your overarching goal should be to deal
with your LDL cholesterol (ideally below 70 units).
In just the first 3 months, the average cholesterol dropped to 174,
with LDL cholesterol dropping 34 points.
As an omnivore, my cholesterol was 218
with LDL higher than HDL, as a vegan it's 117 with HDL high than LDL.
In 2013, an editorial in the British Medical Journal described how the avoidance of saturated fat actually promotes poor health in a number of ways, including through their association
with LDL cholesterol.29 As stated by the author Dr. Aseem Malhotra, an interventional cardiology specialist registrar at Croydon University Hospital in London:
TC 158 (had tested a few weeks later to get NMR and was 170s), LDL - C was in the 70s
with LDL - p around 1,100 if I recall.
«The results indicate that when the cholesterol and particle measures of LDL disagree, the clinical and subclinical outcomes track
with LDL - P more so than
with LDL - C» http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070150/
LDL particles could be totally out of concordance
with LDL blood measurement.
Sadly so many people are walking around
with their LDL in the basement thinking they have nailed it with regard to avoiding heart disease.
Studies on coconut oil actually show an increase in cholesterol with increasing intake.Many of these studies are the same ones used to purport that coconut oil is «heart protective» because HDL increases
with LDL in those studies.
Evolocumab has also had extraordinary success in broad trials,
with LDL cholesterol reductions of up to 60 percent in patients undergoing that treatment.
To estimate the uptake of low - density lipoproteins (LDL) in enhanced hiPS - HEP cells (from C12, C18, and C22) on Days 4, 6, and 12 post-thawing, cells were incubated for 3 or 24 hr
with LDL - DyLight (1:100).
Panel A. Enhanced hiPS - HEP cells from C12 and C18 were incubated for 3 or 24 hr
with LDL - DyLight immediately prior to fixation on Day 6 post-thawing.
However, as
with LDL cholesterol, elevated values lead to an increased risk of cardiovascular disease.
Stitziel noted that these recently approved therapeutics that inhibit PCSK9 were developed after similar genetic studies showed an association
with LDL cholesterol levels.
The drugs would be prescribed to children
with an LDL (the «bad» cholesterol) above 190 milligrams per deciliter, or above 160 with a family history of heart disease.
The study, published online in the journal Arteriosclerosis, Thrombosis, and Vascular Biology, used the LipidSeq method on 313 patients
with LDL cholesterol levels above 5.0 mmol / L who had been referred to the lipid clinic at LHSC.
Robinson says the study found the lives of an additional 4.3 in 1,000 people were saved every year when treated
with LDL cholesterol lowering therapy.
The current NCEP guidelines, published in 2001 and revised in 2004, recommend statins for heart disease patients
with LDL («bad») cholesterol levels greater than 70 milligrams per deciliter of blood and for people who have a moderately elevated risk of heart disease as well as LDL levels above 100 mg / dL.
Beyond the cardiovascular risk associated
with LDL - C, genetic, epidemiologic, clinical and real - world data suggest that patients with elevated triglycerides (TG)(fats in the blood), and TG - rich lipoproteins, are at increased risk for cardiovascular disease.
Not exact matches
In March, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion to include a new indication for adults
with established atherosclerotic cardiovascular disease (myocardial infarction, stroke or peripheral arterial disease) to reduce cardiovascular risk by lowering
LDL - C levels.
Red meat provides us
with healthy fats, in particular, conjugated linoleic acid, or CLA — the trans fat that actually helps improve heart health and reduce belly fat — and stearic acid, a saturated fat that actually reduces
LDL cholesterol.
Avocados contain more potassium than bananas, are full of heart - healthy monounsaturated fats that can lower
LDL cholesterol, are packed
with fiber to keep you full, and can even bring you clearer, healthier skin.
table 2 shows an increase in
LDL cholesterol
with increasing coconut oil.
High intake of regular - fat cheese compared
with reduced - fat cheese does not affect
LDL cholesterol or risk markers of the metabolic syndrome: a randomized controlled trial
When saturated and trans fats in the diet are replaced
with healthier fats (like avocado fat),
LDL cholesterol (the bad kind) can be lowered.
Flavonoids from almond skins are bioavailable and act synergistically
with vitamins C and E to enhance hamster and human
LDL resistance to oxidation
However, numerous studies have demonstrated that eggs tend to raise HDL (good cholesterol) and lower
LDL (bad cholesterol associated
with heart disease).
Polyphenolics» grape seed extract could help lower blood pressure, manage postprandial
LDL cholesterol and glycemic responses among adults
with metabolic syndrome.
This type of fiber is associated
with reduced metabolic syndrome, a reduction in
LDL cholesterol (the bad kind), decreased risk of heart disease, and improved digestive function.
My doctor wanted my cholesterol tested and came back
with numbers that seem EXTREMELY high (noted by *: Cholesterol = 359 *, Triglycerides = 58, HDL Cholesterol = 59,
LDL Cholesterol = 288 *, Cholesterol / HDL = 6.1 *,
LDL / HDL RATIO = 4.88 *, VLDL Cholesterol (Calculated) = 12
Our studies done
with blends of coconut oil
with varying amounts of saturated fatty acids indicate that blood
LDL levels do not increase exponentially
with saturated fatty acid content in oils, he says.
Will coconut oil oil affect triglycerides and
LDL in a negative way if they are already high?very scared they will get higher
with consuming 3 tablespoons a day.
Joseph L. Witztum, an endocrinologist at the University of California, San Diego, argues that people should be treated
with statins early in life to achieve and maintain
LDL cholesterol levels below 50 mg / dL.
Bococizumab significantly reduces cardiovascular events in high - risk patients
with high
LDL cholesterol levels.
A number of studies have shown that
LDL (low - density lipoprotein)-- the «bad cholesterol» —
with apoC - III on its surface is particularly harmful, leading to higher incidence of plaque buildup in artery walls.
But even
with a higher fat intake in the FATFUNC study compared to most comparable studies, the authors found no significant increase in
LDL cholesterol.
In the study, the researchers found that people
with one inactive copy of NPC1L1 appeared to be protected against high
LDL cholesterol — the so - called «bad» cholesterol — and coronary heart disease, a narrowing of the heart's arteries that can lead to heart attacks.
Increased
LDL - C, HDL - C, and possibly TG levels were associated
with a lower risk of diabetes.
Inclisiran lowers low - density lipoprotein (
LDL; «bad») cholesterol for up to one year in patients
with high cardiovascular risk and elevated
LDL cholesterol, according to late - breaking results from the ORION 1 trial presented today in a Hot Line LBCT Session at ESC Congress.
The trial included 501 patients
with atherosclerotic cardiovascular disease (ASCVD) and elevated
LDL cholesterol (> 70mg / ml) despite maximum tolerated statin therapy and patients without ASCVD but
with high cardiovascular risk conditions such as diabetes and familial hypercholesterolaemia in whom
LDL cholesterol was > 100mg / dl despite maximally tolerated statin therapy.
The time averaged reductions in
LDL cholesterol at one year
with a two dose regimen of 100, 200 or 300 mg inclisiran were -31.0 %, -41.1 % and -46.8 %, respectively.