Sentences with phrase «with aberrant»

Law firms do not have the time to deal with aberrant behavior, even on behalf of economically productive lawyers.

These are all also available in genetic variations with aberrant patterning and albinism.

In dogs with aberrant aggression, a large collaborative study at Tufts University has shown a favorable response to thyroid replacement therapy within the first week of treatment, whereas it took about three weeks to correct their metabolic deficit.

These initial results are so promising that complete thyroid diagnostic profiling and treatment with thyroid supplement, where indicated, is warranted for all cases presenting with aberrant behavior.

Similarly to the human system, IBD in dogs may also be associated with aberrant innate immune responses towards commensal enteric bacteria.

The main causes are herpetic infection of the eye, injured cornea with aberrant healing, low tear production (usually associated with herpes), poor tear quality, inability to completely or normally close the eyelids over the eye, insufficient frequency of blinking, or entropion (inward rolling of the eyelid, commonly due to herpesviral infections).

Black comedies typically make the best cult movies, and though this one is filled with aberrant and deviant behavior, it's somehow not quite twisted enough... or at least not properly twisted for viewer fun.

Along with a discussion on PD and the gut - brain axis, no discussion on PD or any other neurodegenerative disease would be complete, as I hope I have demonstrated in previous newsletters, without a discussion on the connection with aberrant tryptophan / kynurenine metabolism.

According to researchers, much evidence points to an association of fast food with aberrant behavior, and fast food increases the risk of depression.

In addition, he presents with an aberrant blind ending bronchus.

In the article describing the work in Molecular Therapy, co-authors Charis Himeda, Takako Jones and Peter Jones highlight the important implications for similar types of genetic diseases: «With increasing evidence that the repeat genome (comprising nearly half the human genome) plays important roles in gene regulation, additional diseases will likely be found associated with aberrant repetitive genomic sequences,» they write.

Publication: Loss of NF - κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT -1-Dependent Manner.

This direct competition - based approach ensures that only ribosomes with aberrant mRNAs are targeted.

«More importantly, these findings encourage the search for personalized music - based interventions for the treatment of brain disorders associated with aberrant dopaminergic neurotransmission as well as abnormal mood and emotion - related brain activity.»

Also, he urged the Regional Executive of the NDC to set up a Disciplinary Committee to deal with aberrant party members out there who were creating confusion.

Not exact matches

That's not to say gene editing is new (it isn't), but Crispr simplifies the process by using molecular scissors that can be precisely targeted to snip out aberrant regions of genetic code, which can then be replaced with the correct sequences.

As the architectural historian Walter C. Kidney once commented, «It was not that he was eccentric; indeed, confronted with Cram, the modern world probably seemed aberrant.»

Historically and theologically we are dealing here with devout yet aberrant forms of faith that are unable to illuminate the more profound problems of human existence, suffering, guilt and destiny or to answer questions about human history in its wholeness.

«frenzies, possessions, mania, melancholy, nerves, delusions, aberrant acts, dramatic tics, passionate loves and hates, sex, visual and auditory hallucinations, fears, phobias, fantasies, disturbances of sleep, dissociations, communion with spirits and imaginary friends, addictions, self - harm, self - starvation, depression».

In the third trial of the nurse home visitor program, nurse - visited, 6 - month - old infants born to mothers with low psychological resources (i.e., maternal IQ, mental health, and sense of efficacy) displayed fewer aberrant emotional expressions (e.g., low levels of affect and lack of social referencing of mother) associated with child maltreatment.18

University of California, Irvine neurobiologists Leslie Thompson and Joseph Ochaba with the Departments of Neurobiology & Behavior and Psychiatry & Human Behavior and their colleagues from UCI and from Children's Hospital of Philadelphia have shown that reducing the aberrant accumulation of a particular form of the mutant Huntingtin protein corresponds to improvement in symptoms and neuroinflammation in HD mice.

Though scientists have managed to come up with drugs that target and turn off aberrant BRAF signaling, cancer cells are clever.

Christianson said his team uses neuroscience techniques «to investigate the biological basis for social cognition with the hope that we can better understand and treat people with conditions marked by aberrant social cognition such as autism or schizophrenia.»

Christianson said the findings set the stage for a large - scale investigation of the brain circuits that work together to orchestrate responses to social emotional information with the hope that such research will lead to better treatment for people with conditions marked by aberrant social cognition, such as autism or schizophrenia.

Aberrant DNA methylation, or abnormal methylation, has been associated with an increased rate of malignancy.

In this rewriting of the textbooks, a tumor is not just a clump of aberrant cells; it also includes a support system, a tumor microenvironment, which encompasses a multitude of varying immune cell types and crisscrossing chemical signals, along with a network of blood vessels.

«If it was just the actions of a few aberrant people, they would either have to believe their superiors condoned what they did, or that they could get away with it because of lack of adequate supervision,» he told the BBC.

What's more, mice with the selective deletion of MHCII in ILCs also developed inflammatory bowel disease, which was driven by aberrant CD4 + T - cell responses to commensal bacteria.

Monstera deliciosa, a tropical plant named for its aberrant leaf shape and tasty fruit, makes the most of the sunshine it receives with the unusual perforations in its leaves.

«An aberrant version of them turns up in suspicious abundance in all the wrong places in brain - tissue samples from patients with brain injuries and major neurological disorders from Alzheimer's and Parkinson's to multiple sclerosis.

The completion of differentiation correlated with less aberrant methylation during the reprogramming process.

In collaboration with Dr. Ke Xu's lab at UC Berkeley, the team determined that this is because of aberrant accumulation and distribution of Ankyrin - G in the AIS.

With hair - thin electrodes, it is now possible to put a pump on the side of them and deliver drugs to the site when there is aberrant activity, quiet it down.

«When Sylvia is concentrating on Bach, something she is familiar with, the signal entering her brain is much more reliable and that constrains the aberrant conversation going on in the two higher areas — and they reconcile themselves to what is actually happening,» says Kumar.

I could imagine that with an electrode array in the right location in the brain, we might learn to understand the differences in neuronal spiking between normal and aberrant brains.

He adds: «Aberrant mRNAs have been found to be particularly common in patients with neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS).

«The advances in transplant techniques and the range of available cell sources that can be used to optimize the treatment of aberrant corneal wound healing can give reassurance to patients with corneal injuries that preserving vision may be possible in the near future,» wrote the authors of the Stem Cells review.

With these tools, Verma is revealing how the aberrant expression of normal cellular genes can causes tumors.

Detection of aberrant hippocampal mossy fiber connections: Ex vivo mesoscale diffusion MRI and microtractography with histological validation in a patient with uncontrolled temporal lobe epilepsy

Discovered that aberrant patterns of neuronal network activity result in profound anatomical and physiological alterations of learning and memory centers and may contribute to cognitive deficits in humans with AD and related mouse models.

Aberrant intrinsic brain activity and cognitive deficit in first - episode treatment - naive patients with schizophrenia.

Xu and her colleagues could duplicate those effects with his cardiac muscle cells in culture, by observing the ability of the drugs to suppress aberrant «calcium sparks.»

Aberrant DNA Methylation in Human iPSCs Associates with MYC - Binding Motifs in a Clone - Specific Manner Independent of Genetics

In addition to being integral to cell biology, tyrosine kinases also present targets for new anticancer therapies: One of the most highly touted, rationally designed anticancer compounds, Gleevec, inhibits an oncogenic tyrosine kinase whose aberrant activity fuels the rampant growth of cells in patients with chronic myeloid leukemia.

Career Goals: Peipei is passionately building up her career as professional research investigator to continue unraveling the mystery of aberrant myelopoiesis with the goal of developing new generation of therapeutic method for cancer & cardiovascular disease.

We are applying an interdisciplinary approach to study the consequences of aberrant activation of the cAMP / CREB / CRTC signal circuit on these adaptive responses and how cooperative signaling with other pathways promotes oncogenic processes in oral, head, and neck cancers.

This is believed to be true given the results of previous RNA - seq experiments (1, 4, 5) along with a belief that the odds are very low that Cas9 would have an off - target that lands in the promoter of another gene, thereby driving aberrant transcription.

The results of her project will help scientists develop novel therapies to target the regulatory proteins that cause CD47 overproduction in leukemia and other cancer stem cells, with the goal of restoring immunosurveillance and enabling the immune system to recognize and destroy these aberrant cancer cells.

Coincident with this, altered immune cell composition aberrant immune localization were detected.

«Despite the growing evidence associating aberrant immunity with behavioral changes in neurological disorders, we did not know the causative link between them,» said Gan.