Sentences with phrase «with abnormal accumulation»

For liver disorders associated with abnormal accumulation of copper, the amount of ingested copper must be minimized.

(3,18; cf. 19,20) Even in visceral fat, it has recently emerged that the obesity - driven rise in inflammation and insulin resistance is associated with an abnormal accumulation of senescent cells, albeit senescent endothelial cells rather than adipocytes.

Crigler - Najjar Syndrome is a rare genetic liver disease (incidence around 1/1 000 000 births) associated with the abnormal accumulation of bilirubin — a yellow pigment produced by the liver — in all the body's tissues, particularly the brain tissues.

Not exact matches

This abnormal binding causes more VCP accumulation on the mitochondria,» Nerve cells with VCP - mutant huntingtin interacting inside them became dysfunctional and self - destructed.

Also, the study is the first to reveal that microRNAs (miRNAs) influence the development of lipodystrophy (abnormal fat accumulation) which affects many people with HIV receiving anti-retroviral therapy.

The problem with making blood stem cells proliferate outside the body is that the artificial growth gives rise to an accumulation of abnormal proteins in a part of the cell called the endoplasmic reticulum, ER.

In the current study, Dr. Santambrogio and her colleagues looked for abnormal accumulations of proteins in the synovial fluid (which bathes the joints) and blood of patients with JIA.

Lewy bodies (accumulation of abnormal alpha - synuclein A protein in the human brain that is associated with the development of Parkinson's.

Figure 2: Abnormal accumulation of the FGFR - TACC fusion protein (red) in glioblastoma stem cells isolated from a primary human glioblastoma with fused FGFR - TACC genes.

We report here that in vitro generated DS neural cells have abnormal metabolism of amyloid - β (Aβ) manifested by increased secretion and accumulation of Aβ granules of Aβ42 pathological isoform with upregulated expression of the APP gene.

Past research has shown that Parkinson's patients with LRRK2 mutations often show an abnormal accumulation of alpha - synuclein as well.

Abnormal accumulation of aluminum has been found in the brains of people with Alzheimer's disease, and when aluminum is injected into the brains of laboratory animals, the animals develop a neurological disease similar to Alzheimer's.

Bloat (dilation) is a condition of an abnormal accumulation of air, fluid, and / or foam in the stomach and can occur with or without the twisting (volvulus) of the stomach.

The cause of microcytosis is not known; however, decreased serum iron concentration, normal to increased ferritin concentration, and accumulation of stainable iron in the liver suggest that microcytosis is associated with abnormal iron metabolism rather than absolute iron deficiency.

This abnormal accumulation eventually interferes with the cell's ability to function.

Patients with hydrocephalus have abnormal accumulation of cerebrospinal fluid (CSF) in the ventricles, or cavities, of the brain.

Thoracostomy tubes can be surgically placed into the animal's chest to provide continuous suction if necessary for patients with persistent abnormal air accumulation.

A surprising number of cats have problems with constipation (abnormal accumulation of feces and difficulty defecating), and similar but more serious conditions such as obstipation (complete obstruction of the colon by feces) and megacolon (damaged nerves and muscles in the colon causing an inability to defecate).