Sentences with phrase «with abnormal development»

Elbow dysplasia is a broad term used to describe three different disease processes associated with the abnormal development of the elbow joint during growth.

Ectodermal dysplasia is a term that covers a wide group of diseases associated with abnormal development of any tissue of ectodermal origin, namely skin, nails and teeth.

These disorders are associated with abnormal development of the brain.

Not exact matches

She found that milestone achievement was abnormal in these monkeys: at six to eight weeks they were slow in starting to manipulate, and at ten months the increase in «motor disturbance behaviors» that normally occurs was prolonged.101 The author concludes, «These effects could occur as a result of effects on vulnerable brain processes during a sensitive period, interference with programming of [normal] brain development by endogenous [internal] agents or alteration in early experiences.»

Maybe the problem is with parents who repeat the patterns their own parents set or with societies who view normal stages of development as somehow abnormal.

Also, the study is the first to reveal that microRNAs (miRNAs) influence the development of lipodystrophy (abnormal fat accumulation) which affects many people with HIV receiving anti-retroviral therapy.

Abnormal number of chromosomes is often associated with cancer development.

Driven by revelations of lead in children's toys, hormone - mimicking chemicals in plastic baby bottles and controversial flame - retardants in furniture, state environmental officials drafted a set of rules aimed at products with chemicals that have been linked to illness or abnormal development

Approximately 42 % of children in the study with MRI findings of MS developed the first clinical symptoms of the disease about two years after the abnormal MRI, which shows a faster development of the disease than has been reported in adults.

«The abnormal inflammation seen in women with PCOS may be a factor in the development of these conditions.»

In a paper published recently in the Journal of Clinical Investigation, lead authors at the University of Georgia, along with colleagues from the Rensselaer and the University of California at San Diego, demonstrated for the first time that the gene NDST1 plays a significant role in the proper development of the diaphragm, and that abnormal expression of the gene could lead to CDH.

Exposure to them during early development is associated with increased risk of cancers and abnormal formation of the reproductive tract.

The involvement of this enzyme in susceptibility to oxidative stress, which has frequently been observed in autistic children, its association with gastrointestinal diseases — which often accompany autistic disorders — and its role in nerve development and neurotransmission mean it is an ideal candidate for deregulation of its expression to lead to the abnormal brain development observed in ASD.

Abnormal levels of the proteins may be useful biomarkers that could help us study early treatments to limit or reverse the damage to brain cells and even prevent the development of the full - blown disease,» said study author Edward Goetzl, MD, a Professor of Medicine with the University of California, San Francisco, a researcher at the National Institute on Aging, and a scientist of NanoSomiX, Inc., a California - based biotechnology company that provided a grant for method development for the study.

Eight physicians and three fellows evaluate and treat children with diabetes, growth disorders, precocious and delayed puberty, sex chromosome disorders (particularly Turner syndrome), abnormal bone development, and other hormonal problems.

Lewy bodies (accumulation of abnormal alpha - synuclein A protein in the human brain that is associated with the development of Parkinson's.

We report here that inner ears of Lcc / Lcc mice fail to establish a prosensory domain and neither hair cells nor supporting cells differentiate, resulting in a severe inner ear malformation, whereas the sensory epithelium of Ysb / Ysb mice shows abnormal development with disorganized and fewer hair cells.

The main birth defect attributed to Zika is microcephaly, a rare neurological condition in which an infant is born with a much smaller head — an effect of abnormal brain development.

The octopus also has an abnormal number of genes controlling neuron development and interactions between neurons — processes likely associated with learning and intelligence.

Although there is substantial evidence from neuroimaging studies that the brain of a child with autism is undergoing abnormal development, little is known about the underlying cellular, molecular and genetic mechanisms that lead to the onset of autistic symptoms.

Knockdown of dynamin - binding protein or Tuba results in abnormal kidney development and other aberrant phenotypes in zebrafish models (middle and right panels) compared with controls (left panel).

«The strong evidence that abnormal TDP - 43 protein is involved in the development of ALS, coupled with models that may replicate ALS more faithfully than other tools, may speed development of therapies for the thousands of individuals diagnosed with this devastating disease.»

For example, a study conducted in his own lab found that forebrain assembloids generated from patients with Timothy syndrome — a genetic disease associated with autism and epilepsy, showed abnormal migration of GABAergic neurons during the development of the cerebral cortex.

When mutated, or not working properly, cells with abnormal tumor suppressor genes are more likely to grow out of control and lead to the development of cancer.

Noting that high estrogen concentrations are «a defining characteristic of dominant follicles,» Dr. Denis Magoffin (Ceders - Sinai Medical Center, Los Angeles, California, USA) and co-investigators examined whether abnormal expression of ERs could contribute to poor follicular development and ovulatory failure in women with PCOS.

Phthalates have been associated with thyroid disorders, premature breast development in baby girls and abnormal sexual development in male fetuses and infants (hypospadias and undescended testes).

Forty - one patients with cancer who were receiving cefoperazone sodium plus mezlocillin sodium were prospectively followed up for the development of abnormal bleeding or hypoprothrombinemia.

Pembroke Welsh Corgis can be afflicted with several eye problems including, cataracts, Progressive Retinal Atrophy which causes eventual blindness, and Retinal Dysplasia, which causes abnormal development of the retina and can lead to blindness also.

Hypertrophic osteodystrophy: a condition of rapidly growing giant breeds where there is an abnormal inflammation of bones with pain and development of excessive bony growths.

With an autosomal dominant disease, if one of the pair of genes is abnormal, this is «dominant» over the normal gene, and results in disease development.

In cats, a condition that results in abnormal blood vessel development to the liver and within the liver can seriously interfere with the organ function.

However, the development of a sequestrum is often associated with corneal trauma, dry eye syndrome, abnormal eyelid conformation, and / or Feline Herpes Virus infection (see «Conjunctivitis and Corneal Disease in Cats»).

Hip dysplasia, or an abnormal growth development of the hip, happens with the ball and socket don't grow at an equal rate, resulting in the two not fitting together properly.

Retinal dysplasia is abnormal development of the sensory retina with focal folds or widespread geographic maldevelopment.

Abnormal clinical signs also may be associated with underlying disease, advanced age, or the development of an unrelated concurrent disease.

This in turn could increase impedance to normal biphasic and pulsatile CSF flow resulting in inhomogeneous flow with abnormal CSF peak velocities predisposing to symptomatic CM and development of syringomyelia.

She recently released her first book, and holds a psychology degree (with an emphasis in child development and abnormal child psychology) from San Diego State University.

Environmental factors may cause this, as occurs in Rutter's autism phenocopy described in Romanian orphans adopted by western families in the early 1990s.1 These children had experienced extreme, profound neglect; after adoption, they began to present to services with abnormal or delayed development.

Rhesus monkeys reared with a «surrogate mother» made of a wire frame covered by cloth - a poor mother substitute - demonstrate abnormal cortisol cycling similar to those of the Rumanian orphans, according to experiments by Gunnar and Stephen Suomi, PhD, Thomas Boyce, PhD, and Maribeth Champaux, PhD, at the National Institute for Child Health and Human Development.

Notably, early problems with language development was one of the few factors significantly associated with peer problems; 23 % of children who were reported to have language difficulties at age 2 had peer problem scores in the borderline or abnormal range at school entry compared with 14 % of those with no language difficulties.

Cross-sectional study of abnormal amygdala development in adolescents and young adults with bipolar disorder

The article then reviews leading programs of research that are concerned with the ways in which early childhood temperament affects psychosocial development, both normal and abnormal.