Sentences with phrase «with acute phase»

Adding sarcosine, but not D - serine, to risperidone improves symptoms in people with acute phase schizophrenia

Patients with the condition have a very high level of this protein, correlating with the acute phases of the disease, and this rate fluctuates according to the inflammatory activity specific to this disease.

Not exact matches

The company's lead product candidate, dilanubicel (NLA101), is currently being evaluated in two ongoing Phase 2 clinical trials in adult and pediatric patients with hematologic malignancies undergoing an allogeneic transplant and adult patients receiving high dose chemotherapy for Acute Myeloid Leukemia.

For the second time in 5 months, Juno Therapeutics has put a clinical hold on a Phase II trial of JCAR015 in adult patients with relapsed or refractory B - cell acute lymphoblastic leukemia due to patient deaths.

After seeing promising results in phase 1 of the Pediatric Leukemia Adoptive Therapy (PLAT - 02) trial with 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia (ALL) achieving complete initial remission, researchers at Seattle Children's are continuing their quest to improve the experimental therapy and reduce the rate of relapse, which is about 50 percent.

Symptoms in travellers with Zika included rash (88 %) and fever (80 %) during the acute phase, and about half complained of muscle or joint pain or headaches.

The strong relationship between adipose tissue macrophage content and indicators of adiposity provides a mechanism for the increased adipose tissue production of proinflammatory molecules and acute - phase proteins associated with obesity.

A Phase 3 Open - label, Multicenter, Randomized Study of ASP2215 versus Salvage Chemotherapy in Patients with Relapsed or Refractory Acute Myeloid Leukemia (AML) with FLT3 Mutation

A Phase 3 Open - Label Randomized Study of Quizartinib (AC220) Monotherapy Versus Salvage Chemotherapy in Subjects with FLT3 - ITD Positive Acute Myeloid Leukemia (AML) Refractory To or Relapsed After First - line Treatment With or Without Hematopoietic Stem Cell Transplantation (HSCT) Consolidawith FLT3 - ITD Positive Acute Myeloid Leukemia (AML) Refractory To or Relapsed After First - line Treatment With or Without Hematopoietic Stem Cell Transplantation (HSCT) ConsolidaWith or Without Hematopoietic Stem Cell Transplantation (HSCT) Consolidation

A Phase I Study of DS - 3201B in Subjects with Acute Myelogenous Leukemia (AML) or Acute Lymphocytic Leukemia (ALL)

A Phase 1/2, Multicenter, Open - label Study of FT - 2102 as a Single Agent and in Combination with Azacitidine or Cytarabine in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome with an IDH1 Mutation

A Phase III Study for Patients with Newly Diagnosed Acute Promyelocytic Leukemia (APL) using Arsenic Trioxide and All - Trans Retinoic Acid

A Phase 1, Multicenter, Open - Label, Safety Study of AG - 120 or AG - 221 in Combination with Induction Therapy and Consolidation Therapy in Patients with Newly Diagnosed Acute Myeloid Leukemia with an IDH1 and / or IDH2 Mutation

A Biomarker - Directed Phase 2 Trial of SY - 1425, a Selective Retinoic Acid Receptor Alpha Agonist, in Adult Patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

A Phase I - II Randomized Trial of a Combination of Nintedanib / Placebo in Combination with Induction Chemotherapy for Patients with Refractory or First Relapse Acute Myeloid Leukemia

CT - 011, developed by Israel - based Curetech Ltd, is also being tested in phase II trials in metastatic melanoma, colorectal cancer in combination with chemotherapy, advanced renal cell and prostate cancers, as well as in acute myeloid leukemia.

A Phase 3, Multicenter, Randomized, Open - Label Study of Guadecitabine (SGI - 110) versus Treatment Choice in Adults with Previously Treated Acute Myeloid Leukemia

Bornhäuser M, Kienast J, Trenschel R, et al Reduced - intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open - label randomised phase 3 trial.

AST - VAC1 (antigen - presenting autologous dendritic cells) is an autologous cancer immunotherapy with promising efficacy and safety data from a Phase 2 study in Acute Myeloid Leukemia (AML).

As anticipated, mice infected with Type II parasites succumbed to infection during both the acute and chronic phase.

Her interests in the laboratory included strategies to eradicate HIV - 1, with a focus on the HIV - 1 reservoir in HAART - treated patients from acute or chronic phase infection.

A phase I / II trial of KTE - C19 (anti-CD19 CAR T cells) for pediatric and adolescent subjects with relapsed / refractory B - precursor acute lymphoblastic leukemia -LRB-

Treatment of acute traumatic brain injury with the hormone progesterone provides no significant benefit to patients when compared with placebo, a NIH - funded phase III clinical trial has concluded.

This group includes patients with advanced myeloproliferative neoplasms (accelerated phase, blast phase, or post — myeloproliferative neoplasm acute myeloid leukemia) characterized by poor outcomes and aggressive disease.

However, the second form of immune selection — passage of acute - phase parasites from hosts injected with antiserum at the beginning of the infection — yielded parasites with lower virulence to naïve mice than their ancestors in one study (Wellde and Diggs 1978), although it had no impact on virulence in two other studies (see Briggs and Wellde 1969).

Furthermore, it is usually associated with elevated levels of pro-inflammatory cytokines and acute phase proteins, such as interferons (IFNs), interleukin (Il)-1, Il - 6, tumor necrosis factor - α (TNF - α), and C - reactive protein (CRP).

Celiac disease patients have higher concentrations of serum zonulin during the acute phase of disease compared with their healthy counterparts, and also have over-expressed CXCR3, the intestinal receptor for gliadin (Fasano, 2011).

A few Refs: http://labtestsonline.org/understanding/analytes/ferritin/tab/test «Ferritin is an acute phase reactant and thus may be increased in people with inflammation, liver disease, chronic infection, autoimmune disorders, and some types of cancer»

Elevated serum ferritin (storage form of iron in the blood) acts as an acute phase reactant and has been associated with increase risk of stroke, diabetes, and decreased cardiovascular fitness.

I mean, in the acute, most miserable phase of the flu you don't have enough energy to worry about something as trivial as going crazy, what with sneezing and coughing and camping out on the sofa overdosing on bad TV... By the time cabin fever sets in, you're on the road to recovery, just way too slowly.

Acute Care: students assist with the phase from diagnosis of a brain injury through discharge from a hospital or rehabilitation facility

If your pet is diagnosed with pancreatitis, it will usually be treated in - hospital at least during the acute phase.

Bathen - Noethen A, Carlson R, Menzel D, Mischke R, Tipold A. Concentrations of acute - phase proteins in dogs with steroid responsive meningitis - arteritis.

Acute conditions usually subside quickly, typically within one phase of treatments, while chronic conditions can be controlled with regular treatments.

Ehrlichiosis can be detected with a blood test; however, a positive result may not occur for two to three weeks into the acute phase.

Many of the symptoms present in the acute phase may return along with lameness, anemia, swollen limbs and blood clotting problems.

The only treatments for acute - phase MDD with high strength of evidence were second - generation antidepressants (figure 2).

We will exclude trials with treatment duration of less than 4 weeks, because the onset of benefit for most antidepressants often takes at least 4 weeks.31 If a study presents data for more than one time point within our predefined acute phase window or beyond 16 weeks, the 8 week (or the closest to 8 week) will be taken as the time.

Therapy services assessed in this initial phase ranged from acute care to work hardening and included patients with a wide variety of upper extremity diagnoses.