This may sound unappealing, but for
those with aldosterone or sodium deficiency it will likely taste great.
I am also wondering if supplementing
with aldosterone would help.
Findings from the Treatment of Preserved Cardiac Function Heart Failure
with an Aldosterone Antagonist (TOPCAT) trial, have revealed that adding the medication known as spironolactone (Aldactone) to existing therapy did not significantly reduce the composite time to either death from cardiovascular causes, surviving a cardiac arrest, or hospitalization to manage heart failure in patients with heart failure and a preserved ejection fraction in a study funded by the National Heart, Lung and Blood Institute, National Institutes of Health.
A late - breaking clinical trial, known as the Treatment of Preserved Cardiac Function Heart Failure
with an Aldosterone Antagonist (TOPCAT) trial, to be presented at the American Heart Association (AHA) Scientific Sessions, November 18, 2013, demonstrates that spironolactone did not reduce the primary outcome of cardiovascular death, heart failure hospitalization, nor surviving a cardiac arrest in patients with heart failure and preserved ejection fraction (pump function).
Not exact matches
Past research, Kopf said, shows the elevating circulating
aldosterone levels are associated
with high blood pressure, blood clot formation, thickening of the heart muscle (called cardiac hypertrophy) and congestive heart failure.
People who have primary adrenal insufficiency and a confirmed
aldosterone deficiency should undergo replacement therapy — typically
with the synthetic hormone fludrocortisone — to maintain the body's salt and water balance.
If you are struggling
with maintaining a healthy blood pressure, and also have changes in blood potassium levels, you may want to talk to your doctor about
aldosterone.
What
aldosterone does is it tells the kidneys to retain sodium and excrete potassium, but if
aldosterone is low, then they tend to excrete sodium and retain potassium, and
with sodium will always follow, water will always follow it.
Drugs are often used to lower
aldosterone levels in individuals
with hypertension.
But
with low
aldosterone, I will tell you, you have a hard time holding on to your water.
Individuals who struggle
with too low of blood pressure, often have either an inability to produce and utilize
aldosterone.
Now guys, it sounds like, right now, the recommendations that you're making would be to follow up this series of tests
with yet another test, a lymphocyte subset panel, and then also look into something like enhancing my body's intake of glutathione or glutathione precursors along
with, perhaps for this
aldosterone side issue, adding in some sea salts and some trace minerals.
Your cortisol, however, these are both adrenally produced hormones, your cortisol is high, but your
aldosterone is a little bit low, which is really curious and paints kind of a larger picture as to possibly what's going on
with this.
Aldosterone reverses certain types of hearing loss inn experimental animals100, 101, 102, 103, and levels of serum aldosterone have been inversely correlated with degree of hearing in humans.104 Case studies at Tahoma Clinic, Renton, Washington, have found that a significant percentage of individuals with hearing loss and low levels of aldosterone recover some of their hearing when exogenous aldosterone i
Aldosterone reverses certain types of hearing loss inn experimental animals100, 101, 102, 103, and levels of serum
aldosterone have been inversely correlated with degree of hearing in humans.104 Case studies at Tahoma Clinic, Renton, Washington, have found that a significant percentage of individuals with hearing loss and low levels of aldosterone recover some of their hearing when exogenous aldosterone i
aldosterone have been inversely correlated
with degree of hearing in humans.104 Case studies at Tahoma Clinic, Renton, Washington, have found that a significant percentage of individuals
with hearing loss and low levels of
aldosterone recover some of their hearing when exogenous aldosterone i
aldosterone recover some of their hearing when exogenous
aldosterone i
aldosterone is taken.105
Higher serum
aldosterone correlates
with lower hearing thresholds: a possible protective hormone against presbycusis..
When your body is so pre-occupied
with manufacturing cortisol, it has no reserves for making other important hormones and neurotransmitters like
aldosterone, testosterone and epinephrine which are so invaluable for keeping stress under control.
Another consequence of low
aldosterone is electrolyte imbalance and cell dehydration, which both have negative effects on almost all physiological reactions in the body: aside from salt cravings, low blood pressure and light - headedness, patients
with adrenal fatigue often experience an irregular heart beat, lethargy, muscle weakness, and increased thirst.
Cortisol works
with the hormone
aldosterone to balance your electrolyte levels — so when you're hungover, your body churns out more cortisol.
This peptide generates similar increases in growth hormone secretion, but without the appetite stimulation and increase in cortisol, acetylcholine, prolactin, and
aldosterone seen
with other peptides in its class.
A craving for salt in people
with adrenal fatigue is usually due to low
aldosterone.
So people
with adrenal fatigue have hard time produce
aldosterone = they can't retain sodium.
The adrenal glands help the body deal
with stress and illness by producing the steroids, cortisol and
aldosterone.
Lack of
aldosterone can result in hyperkalemia
with an increase in total body potassium.
If your dog has typical Addison's disease, where both
aldosterone and cortisol are deficient, most veterinarians will stabilize the pets
with monthly injections of desoxycorticosterone pivalate (DOCP).
There is a human oral medication, fludrocortisone acetate (Florinef), that replaces both the
aldosterone and the cortisol
with a single drug.
Dogs
with secondary or atypical Addison's disease still produce sufficient
aldosterone.
It is also common for dogs
with the pituitary form of Addison's to also continue to make sufficient
aldosterone (mineralcorticoid).
Her research interests include management of congestive heart failure
with particular interest in the renin - angiotensin -
aldosterone system as well as advanced cardiac imaging.
Blood pressure, heart rate, serum chemistries and urinary
aldosterone excretion, as a measure of RAAS activation, were compared
with baseline values.
She completed a master's degree in biomedical sciences
with research on the effects of trilostane and mitotane on
aldosterone in canine Cushing's disease.
With complete adrenocortical destruction, the dog develops both cortisol and
aldosterone deficiencies.
If your dog is diagnosed
with Addison's, she may need to be on a lifelong replacement of both cortisol and
aldosterone.