Sentences with phrase «with all genes intact»

The control mice, with all genes intact, should have lost sight as photo - receptors — the light - sensitive cells in the retina — died.

When Bäckhed and Gordon bred mice lacking a functional FIAF gene, the mice were more than 50 % flabbier than mice with the gene intact.

Not exact matches

Next, they grafted this lab - grown gene - altered skin onto mice with intact immune systems.

A few of those chromosomes have stayed intact — with their genes in the same order — over the past 105 million years, at least in orangutans and humans.

And the changes are handed down: While most of the chimp genome's 24 pairs of chromosomes undergo a genetic reshuffling during the production of sperm and eggs, with genes swapped between the two copies, there is only one Y chromosome and thus no mixing — the Y is transmitted intact.

Goto told Iritani his vision: find mammoth sperm with genes still intact and use it to fertilize a living elephant egg.

While fully intact Ebola virus is a biosafety level (BSL) 4 pathogen and dangerous to work with, the team created a virus - like particle comprised of the Ebola proteins (glycoproteins and matrix proteins) that enable the virus to enter cells, but without many of the genes and proteins that make the virus deadly.

In the R5 - ZFN control group, with intact cxcr4 genes, 88 % of CD4 + T cells expressed CXCR4 protein at day 27 post engraftment, compared to 84 % of cells in the X4 - ZFN mice (∼ 24 % cxcr4 gene disruption) as determined by a fluorescence minus - one (FMO) control.

They can ensure that only bacteria with intact synthetic gene circuits survive, or confine bacteria to a target environment at 37 °C (body temperature) while inducing them to die at lower temperatures, as demonstrated during bacterial exit from a mouse intestinal tract.

While there are noticeable changes in gene expression associated with PMI, we nonetheless found that the characteristic transcriptional signature of tissues remains largely intact through the PMI intervals considered here.

GenSight's treatment is for people with damaged photoreceptor cells but intact ganglion cells; it inserts the gene into the ganglion cells, whose axons form the basis of the optic nerve.

Characterization of complementing and non-complementing YAC transgenic families revealed that correction of the inv mutant phenotype was concordant with integration and intact expression of this novel gene, which we have named inversin (Invs).

The challenge then is to replace the intact, functional gene in the mouse chromosome with the modified version created in the test tube.