The only documented long - term complete remissions reported in multiple myeloma patients have occurred
with allogeneic bone marrow transplantation, where a donor's blood stem cells (graft) are transplanted into the patient (host) with multiple myeloma.
Not exact matches
Allogeneic bone marrow transplant (BMT) is an essential treatment to cure patients
with blood cancers such as leukemia.
Collaboration
with Hematology and
Bone Marrow Transplantation Unit research group in molecular diagnostics applied to the management of patients undergoing
allogeneic SCT, especially for the detection of minimal residual disease and early relapse.
In close collaboration
with universities and physicians world - wide, our comprehensive investigational stem cell treatments employ well - targeted combinations of
allogeneic human umbilical cord stem cells, autologous
bone marrow stem cells, and autologous adipose stem cells for the diseases listed below.
Dr. Goodman is also involved in collaborative efforts
with the San Antonio
Bone Marrow Transplant Center to study the outcome of allogeneic bone marrow transplants following a relapse from autologous bone marrow transpla
Bone Marrow Transplant Center to study the outcome of allogeneic bone marrow transplants following a relapse from autologous bone marrow transp
Marrow Transplant Center to study the outcome of
allogeneic bone marrow transplants following a relapse from autologous bone marrow transpla
bone marrow transplants following a relapse from autologous bone marrow transp
marrow transplants following a relapse from autologous
bone marrow transpla
bone marrow transp
marrow transplants.
Reconstitution
with syngeneic plus
allogeneic or xenogeneic
bone marrow leads to specific acceptance of allografts or xenografts.
In the future, outpatient blood and
bone marrow stem cell transplantation will be offered to a broader group of patients
with other blood disorders and for
allogeneic transplants (transplant from non-twin donor stem cells).
Patients receive one of two types of stem cell - based transplants: autologous, in which a patient donates and receives back his / her own stem cells; or
allogeneic, in which
bone marrow - derived stem cells come from a related or unrelated donor whose human leukocyte antigens (HLA) are genetically matched
with those of a patient.
Ponatinib Extends Survival Over Transplant in Chronic Phase CML: The results of a new study that included patients from the PACE trial and the European
Bone Marrow Transplant registry revealed that treatment
with ponatinib yielded better overall survival (OS) compared
with allogeneic stem cell transplantation (allo - SCT) in patients
with chronic phase chronic myeloid leukemia (CP - CML)
with a T315I mutation.