Conditional survival and excess mortality after high - dose therapy
with autologous stem cell transplantation for adult refractory or relapsed Hodgkin lymphoma in Norway.
A national study on conditional survival, excess mortality and second cancer after high dose therapy
with autologous stem cell transplantation for non-Hodgkin lymphoma.
Pattern of employment and associated factors in long - term lymphoma survivors 10 years after high - dose chemotherapy
with autologous stem cell transplantation.
Not exact matches
«I'm working
with Professor Richard Oreffo and Dr Rahul Tare from the University's Centre for Human Development,
Stem Cells and Regeneration who are trying to create and grow cartilage in the lab using a patients» own (autologous) stem cells to then be implanted back into the patient if they have a cartilage defect,» she expla
Stem Cells and Regeneration who are trying to create and grow cartilage in the lab using a patients» own (autologous) stem cells to then be implanted back into the patient if they have a cartilage defect,» she expl
Cells and Regeneration who are trying to create and grow cartilage in the lab using a patients» own (
autologous)
stem cells to then be implanted back into the patient if they have a cartilage defect,» she expla
stem cells to then be implanted back into the patient if they have a cartilage defect,» she expl
cells to then be implanted back into the patient if they have a cartilage defect,» she explains.
«If we win, the entire regulatory structure for
autologous cell processing,
with or without culture, will be rewritten such that any physician using good practices and treating patients responsibly can use
stem cells as part of his or her medical practice,» he says.
For this analysis, 605 patients
with newly diagnosed multiple myeloma and treated
with continuous lenalidomide (brand name Revlimid) following
autologous stem cell transplant were compared to 604 patients who were treated
with placebo or no maintenance.
«Lenalidomide maintenance following
autologous stem cell transplant can now be considered a standard of care for people
with multiple myeloma,» says Dr. McCarthy, senior author on the meta - analysis and Principal Investigator of the U.S. study, CALGB (Alliance) 100104.
Results from a clinical trial investigating a new T
cell receptor (TCR) therapy that uses a person's own immune system to recognize and destroy cancer
cells demonstrated a clinical response in 80 percent of multiple myeloma patients
with advanced disease after undergoing
autologous stem cell transplants (ASCT).
The investigational treatment was combined
with chemotherapy and an
autologous stem cell transplant — a new strategy designed to target and kill the
cells that give rise to myeloma
cells.
The therapy is approved by the U.S. Food and Drug Administration for relapsed or treatment - resistant Hodgkin lymphoma, and it is commonly prescribed to patients whose disease has progressed after
autologous stem cell transplant, a procedure that replenishes the bone marrow
with the patient's own healthy
stem cells after therapy.
The treatment in the current study, called
autologous hematopoietic
stem cell transplantation (AHSCT), was given to patients
with advanced forms of the disease that had failed to respond to other medications.
«
Autologous stem cell transplant should be standard care for HIV - associated lymphoma: Multicenter, Phase II trial suggests autologous transplant should be standard of care for HIV patients with relapsed / treatment - resistant lympho
Autologous stem cell transplant should be standard care for HIV - associated lymphoma: Multicenter, Phase II trial suggests
autologous transplant should be standard of care for HIV patients with relapsed / treatment - resistant lympho
autologous transplant should be standard of care for HIV patients
with relapsed / treatment - resistant lymphoma.»
However, these problems associated
with histocompatibility may be solved using
autologous donor adult
stem cells, therapeutic cloning,
stem cell banks or more recently by reprogramming of somatic
cells with defined factors (e.g. induced pluripotent
stem cells).
Based on our data,
autologous stem cell transplant should be considered the standard of care for patients
with HIV - related lymphomas for the same indications and under the same circumstances that we would use it in patients without HIV infection.»
Along
with the investigational monoclonal antibody, study participants underwent multi-drug chemotherapy, surgery, radiation and
autologous hematopoietic
stem cell transplantation.
In addition, transgenic
autologous hematopoietic
stem cells can be successfully transplanted in HIV - infected individuals [18] and several phase I adoptive transfer trials of CD4 + T
cells treated
with R5 - ZFNs in HIV infected individuals are currently underway.
Tan J, Wu W, Xu X, Liao L, Zheng F, Messinger S, Sun X, Chen J, Yang S, Cai J, Gao X, Pileggi A, Ricordi C. Induction therapy
with autologous mesenchymal
stem cells in living - related kidney transplants: a randomized controlled trial.
Plerixafor has been approved by the FDA as the first small - molecule CXCR4 antagonist for use in combination
with granulocyte - colony stimulating factor (GCSF) to mobilize hematopoietic
stem cells to the bloodstream for collection and subsequent
autologous transplantation in patients
with non-Hodgkin's lymphoma and multiple myeloma.
We published the first experience
with double
autologous peripheral blood
stem cell transplant for high - risk neuroblastoma.
In close collaboration
with universities and physicians world - wide, our comprehensive investigational
stem cell treatments employ well - targeted combinations of allogeneic human umbilical cord
stem cells,
autologous bone marrow
stem cells, and
autologous adipose
stem cells for the diseases listed below.
In 2016, the Food and Drug Administration (FDA), the branch of government charged
with regulating cellular therapies, took action to address these issues, proposing revised guidelines that could change how
stem cells, especially
autologous stem cells, are regulated.
Biological markers of Mesenchymal Stromal
Cells as Predictors of response to
Autologous Stem Cell Transplantation in Patients
with Amyotrophic Lateral Sclerosis; an Investigator - Initiated Trial and in Vivo Study.
Around 5 - 10 % of patients
with solid tumors who are treated
with chemotherapy, radiation or
autologous stem cell transplantation develop treatment - related MDS or AML.
Diagnosed
with multiple myeloma or lymphoma and prescribed an
autologous stem cell transplant (patient receiving their own
stem cells)
Allogeneic Mesenchymal
Stem Cells Stimulate Cartilage Regeneration and Are Safe for Single - Stage Cartilage Repair in Humans upon Mixture
with Recycled
Autologous Chondrons.
The US Food and Drug Administration (FDA) has granted Priority Review designation for tisagenlecleucel (Kymriah), formerly known as CTL019, for treatment of adult patients
with relapsed or refractory diffuse large B -
cell lymphoma (DLBCL) who are ineligible for, or have relapsed after,
autologous stem cell transplant.
Review of «Biological markers of Mesenchymal Stromal
Cells as Predictors of response to
Autologous Stem Cell Transplantation in Patients
with Amyotrophic Lateral Sclerosis; an Investigator - Initiated Trial and in Vivo Study» from
Stem Cells by Stuart P. Atkinson
Patients receive one of two types of
stem cell - based transplants:
autologous, in which a patient donates and receives back his / her own
stem cells; or allogeneic, in which bone marrow - derived
stem cells come from a related or unrelated donor whose human leukocyte antigens (HLA) are genetically matched
with those of a patient.
I was diagnosed
with non-Hodgkin's diffuse B -
cell lymphoma on Aug. 14, 2015, and since then, I have undergone three rounds of chemotherapy, 22 radiation treatments and an
autologous stem cell transplant.
High - Dose Chemotherapy Plus Transplant Not Recommended for DLBCL: The results of an Italian study report that treatment of high - risk diffuse large B -
cell lymphoma (DLBCL)
with abbreviated course of rituximab dose - dense chemotherapy plus high - dose cytarabine, mitoxantrone, and dexamethasone (R - MAD) plus carmustine, etoposide, cytarabine, and melphalan (BEAM) plus
autologous stem cell transplantation compared
with a full course of rituximab dose - dense chemotherapy did not improve overall survival.
CRP Levels Before Transplant Linked
With Survival in Multiple Myeloma: According to a new study, patients with an elevation in C - reactive protein (CRP) prior to an autologous stem cell transplantation (ASCT) for multiple myeloma experienced a worse overall survival (OS) r
With Survival in Multiple Myeloma: According to a new study, patients
with an elevation in C - reactive protein (CRP) prior to an autologous stem cell transplantation (ASCT) for multiple myeloma experienced a worse overall survival (OS) r
with an elevation in C - reactive protein (CRP) prior to an
autologous stem cell transplantation (ASCT) for multiple myeloma experienced a worse overall survival (OS) rate.
The technique involves replacing a mutated copy of the gene
with a healthy copy in
stem cells isolated from the patient, which are then transfused back into the body — a process known as
autologous stem cell transplantation.
This is the «show reel» of Dr Haluk Deda, a Turkish neurosurgeon who is setting up shop in Dubai, where he plans to offer
autologous stem cell transplants to treat chronic spinal cord injuries and ALS, a condition
with no known cure that generally leads to death within three to five years of diagnosis.
Unmatched performance — high transfection efficiency &
cell viability in primary cells Fully scalable — from R&D to the clinic without reoptimization Safe — non-viral cell engineering in closed, sterile, computer - controlled environment Cell loading flexibility — mRNA, gRNA, siRNA, DNA, proteins, cell lysates, and small molecules into autologous or allogenic immune, stem / progenitor, or somatic cells Regulatory ease — Master File designation with the CBER Division of the U.S. FDA, cleared by NIH's RAC and Health Canada, cGMP - compliant, and CE - ma
cell viability in primary
cells Fully scalable — from R&D to the clinic without reoptimization Safe — non-viral
cell engineering in closed, sterile, computer - controlled environment Cell loading flexibility — mRNA, gRNA, siRNA, DNA, proteins, cell lysates, and small molecules into autologous or allogenic immune, stem / progenitor, or somatic cells Regulatory ease — Master File designation with the CBER Division of the U.S. FDA, cleared by NIH's RAC and Health Canada, cGMP - compliant, and CE - ma
cell engineering in closed, sterile, computer - controlled environment
Cell loading flexibility — mRNA, gRNA, siRNA, DNA, proteins, cell lysates, and small molecules into autologous or allogenic immune, stem / progenitor, or somatic cells Regulatory ease — Master File designation with the CBER Division of the U.S. FDA, cleared by NIH's RAC and Health Canada, cGMP - compliant, and CE - ma
Cell loading flexibility — mRNA, gRNA, siRNA, DNA, proteins,
cell lysates, and small molecules into autologous or allogenic immune, stem / progenitor, or somatic cells Regulatory ease — Master File designation with the CBER Division of the U.S. FDA, cleared by NIH's RAC and Health Canada, cGMP - compliant, and CE - ma
cell lysates, and small molecules into
autologous or allogenic immune,
stem / progenitor, or somatic
cells Regulatory ease — Master File designation
with the CBER Division of the U.S. FDA, cleared by NIH's RAC and Health Canada, cGMP - compliant, and CE - marked
The strongest challenge to this approach, granting the periodic replenishment of somatic
stem -
cell pools
with autologous but OncoSENS - ready
stem cells, has been the possible existence of functions of TERT (telomerase reverse transcriptase — the catalytic subunit of telomerase), other than the lengthening of telomeres itself.
Their research focused on evaluating the safety and efficacy of
autologous bone marrow - derived
stem cell transplantation in individuals
with type 2 diabetes
with good glycemic control as well, which emerged as an important aspect in the transplantation group as well as in the non-transplanted group.
Title: Transplantation and Tracking of
Autologous Epidermal Neural Crest
Stem Cells into the Spinal Cord of Dogs
with Acute Severe Spinal Cord Injury
Additionally, non-interventional treatments such as
Autologous Conditioned Plasma (ACP),
stem cell therapy, and rehabilitation / conditioning are proven treatment modalities that are coupled
with surgical intervention or used alone as primary treatment.
Core Paws learned about an
Autologous Stem Cell Therapy via MediVet Biologics that was working miracles in animals
with arthritis.
After experiencing how
autologous adult
stem cell therapy helped a loved one struggling
with Multiple Sclerosis regain their life quality, Stemedix was founded
with the determination to help offer this alternative therapy to others around the world suffering from debilitating diseases.
Is it feasible to conduct a randomised controlled trial of pretransplant exercise (prehabilitation) for patients
with multiple myeloma awaiting
autologous haematopoietic
stem cell transplantation?