Sentences with phrase «with bacterial gene»

This form of interference with bacterial gene regulation is also of pharmaceutical interest as it is known that pathogenic bacteria can protect themselves against attack by the immune system and the effect of antibiotics by forming biofilms, for instance on the epithelium of the respiratory system.

In 2010, the environment ministry put on hold the commercial planting of GM brinjal, an eggplant variety, equipped with a bacterial gene that thwarts insect pests.

The most recent breakthrough was made by a team of British and American biologists who report they've successfully infused tobacco plants with bacterial genes — a first step towards engineering crops that grow faster, offer higher yields and use less fertilizers.

Not exact matches

Clark also tested his own blood, where he found traces of B. burgdorferi along with another distinct genospecies (a bacterial species separated by divergence of genes), Borrelia andersonii, usually found in rabbits.

The results show — for the first time, Briggs thinks — that the bacterial genomes change with depth: the micro-organisms at 554 metres carry more mutations in genes that code for energy - related processes like cell division and biosynthesis of amino acids than are seen in their shallower counterparts.

Three options are on the table: tweak cereals so that they form symbiotic partnerships with rhizobia as legumes do; colonise cereal roots with other types of nitrogen - fixing bacteria; or transfer the bacterial genes that make fertiliser directly into the crop plants.

Bacteria expressing enzyme in one cell (bright green), while genetically identical cells do not, remaining protected from antibiotic onslaught; image courtesy of Yuichi Wakamoto / Neeraj Dhar / John McKinney Some strains of nasty bacterial infections, such as MRSA (methicillin - resistant Staphylococcus aureus), come loaded with resistance to antibiotics built right into their genes.

A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep - vein thrombosis — the formation of a harmful clot in a deep vein.

When Fishel and Kolodner heard of the accumulation of mutations in cancer cells from patients with familial colon cancer, they suspected that the gene responsible would be similar to the bacterial and yeast genes they had studied.

We're still struggling with the smallest bacterial cell, in which we don't know what even one - fifth of the genes do.

With the acquisition of a number of key genes and lipids from a bacterial symbiont, it would be possible for Loki - type cells to evolve a primitive membrane trafficking machinery and compartmentalization.»

To determine how similar a person's fingertip bacteria are to bacteria left on computer keys, the team took swabs from three computer keyboards and compared bacterial gene sequences with those from the fingertips of the keyboard owners.

The putative archaeal host existed in a stable symbiotic relationship with one or more bacterial species, with the capacity for both gene and lipid exchange between species.

The islands are now free to move into other bacterial cells, bringing with them new sets of genes.

The Duke team has previously explored blood tests to examine a patient's RNA for gene signatures to distinguish bacterial and viral infections in the upper respiratory tract and is working with a private company to develop potential diagnostics.

These crops, being embraced by big agriculture in the U.S., carry genes that imbue them with resistance to herbicides and lace their tissues with a bacterial toxin harmless to humans but fatal to pests that may try to feed on them.

He says this idea has «very profound» implications for the debate over the origins of bacterial genes that are present in the human genome but absent in our closest relatives (Science, 8 June, p. 1903): The amount of conjugation Waters detected is «high enough to readily explain» the possible infiltration of bacterial genesinto our DNA, meaning that conjugation could have happened quickly enough to add genes only to humans, in the years since they split from the common ancestor they shared with chimpanzees.

Bacterial conjugation relies on a ring of DNA called a plasmid with the genes necessary to build the mating bridge and shoot DNA across it.

Although Jack and Malcolm had never met F2F, they were a tight team with a good rep on the Distributed Biology Network: gene hunters who amplified bacterial DNA from soil and water samples, shotgun sequenced it, and identified genes that weren't in the catalogs.

Ten classifier genes distinguished infants with bacteremia from those without bacterial infections in the test set.

Wick continues: «Our study shows that fungal hyphae not only provide soil bacteria with an excellent infrastructure, but also a potential hot spot for bacterial horizontal gene transfer.

UCLA scientists used DropSynth to make thousands of bacterial genes with different versions of phosphopantetheine adenylyltransferase, or PPAT (pictured).

Sixty - six classifier genes were identified that distinguished infants with and without bacterial infections in the test set.

Bacteria share DNA with other organisms with which they come into contact, so an antibiotic - resistant gene can transfer from one type of bacterium to another, and a bacterial cell can become resistant to numerous antibiotics at once.

The new method circumvents the problem of not being able to culture many of these bacteria in the lab by transferring genes from these bacteria into another bacterial species that is easier to work with.

It is the bacterial equivalent of sex, with two cells sidling up to each other and engaging in conjugation, or the swapping of genes, except that they do not have to wait for progeny to see the benefits.

It turns out that Monocercomonoides has come up with a workaround by borrowing some bacterial genes that perform the same function, the scientists reveal online today in Current Biology.

In one of the most elaborate feats of synthetic biology to date, a research team has engineered yeast with a medley of plant, bacterial, and rodent genes to turn sugar into thebaine, the key opiate precursor to morphine and other powerful painkilling drugs that have been harvested for thousands of years from poppy plants.

It is much longer and more complex than most viral or bacterial genes, and it has sequences with which other spider genes can interact.

That won't happen with the engineered variety because it carries a bacterial gene encoding an enzyme that detoxifies bromoxynil.

Researchers have speculated that they could reverse this process with bacterial DNA - cutting enzymes they have adapted for adding and subtracting genes from mice and other multicelled organisms.

Whilst such studies provide a reservoir of genes involved in bacterial recognition and degradation in vitro the situation in vivo where hemocytes can interact with other immune cells to optimize immune responses is likely to be more complex.

In the current paper, Hind used Yellow Pear tomatoes together with a wild relative of tomato called Solanum pimpinellifolium to identify the FLS3 gene and show how it functions to reduce bacterial growth.

Once the bacterial cell signaling protein cagA reaches the host cytosol, it is capable of altering subsequent generations of progenitor cells, leading to the development of cancer through changes in mitotic activity, apoptosis, cellular assembly, and signaling.26 Although it should be noted that while the presence of the cagA protein doubles the risk of gastric cancer, cagA - negative strands also increase the risk of distal gastric cancer.27 Additional H pylori virulence factors include babA2, which encodes bacterial adhesion with gastric epithelial cells, and vacuolating cytotoxin A, which is encoded by the gene vacA.28, 29 H pylori strains carrying some combination of the babA2, cagA, and vacA genes were associated with the highest risk of developing intestinal metaplasia.

Brady and coworkers amplify and sequence bacterial DNA from environmental soil samples and then look for gene clusters that encode enzyme systems likely to biosynthesize natural products with preselected characteristics.

Researchers have shown they can distinguish between viral and bacterial infections in children with fever by profiling the activity of genes in a blood sample.

«We were not terribly surprised by the resistance genes that track with bacterial family trees.

When scientists at the University of Delhi in India took soil samples from a pesticide dump and compared them with samples from a cleaner control site, they reported that the soil from the waste site contained a higher concentration of gene sequences from certain bacterial groups, such as Pseudomonas, Novosphingobium and Sphingomonas, that are known to degrade common pesticides like hexachlorocyclohexane.

They can ensure that only bacteria with intact synthetic gene circuits survive, or confine bacteria to a target environment at 37 °C (body temperature) while inducing them to die at lower temperatures, as demonstrated during bacterial exit from a mouse intestinal tract.

In bacteria, the ligand - PBP complex develops high affinity for transmembrane proteins such as Trg, and the chimeric Trg - HK protein allows activation of gene expression with one additional protein, a bacterial response regulator [5].

METHODS: Gene gun immunization is conducted with transgenic mice using the Abeta42 gene in a bacterial plasmid with the pSP72 - E3L - Abeta42 constrGene gun immunization is conducted with transgenic mice using the Abeta42 gene in a bacterial plasmid with the pSP72 - E3L - Abeta42 constrgene in a bacterial plasmid with the pSP72 - E3L - Abeta42 construct.

Working with Carla Guimaraes from Whitehead Member Hidde Ploegh's lab, Carette subjected knockout cells to several bacterial toxins to identify resistant cells and therefore the genes responsible.

In the picture depicted, one of the two copies of the gene of the mouse was replaced with the lac Z cassette expressing the bacterial beta galactosidase and its activity in the kidney is followed by staining.

A Hex cDNA with a recognition sequence for bacterial BirA ligase was linked via an artificial IRES consisting of a tandem array of repeated Gtx sequences to the gene encoding Venus followed by a cytomegalovirus driven hygromycin - thymidine kinase dual selection cassette flanked by loxP sites.

The results of 16S rRNA gene sequencing revealed an increase in the relative abundance of the Gram - negative bacterial order Verrucomicrobia and Bacteriodetes, with a reduction in the Gram - positive order Firmicutes.

Functional analysis showed significant differences between the metagenomes and the downstream bacterial communities contained a high abundance of genes associated with antibiotic resistance (COG0294, 3570, 3231, 1357), replication and mobilization of DNA (COG3668, TIGR01629, TIGR02768) and membrane transporters (COG0488, TIGR02294)(Tables S6, S7, S8, S9, S10, S11).

Taken together, our data shows that exposure to effluent contaminated with antibiotics promote resistance genes in environmental bacterial communities.

We selected 68 genes with putative immune - related functions, macroarrayed them and determined their expression profiles following bacterial or trypanosome challenge.

As more researchers identify bacterial genes with interesting functions, we can think about how to manipulate them natively for therapeutic treatments.»

We investigated the distal gut bacterial communities of three healthy humans before and after treatment with ciprofloxacin, obtaining more than 7,000 full - length rRNA sequences and over 900,000 pyrosequencing reads from two hypervariable regions of the rRNA gene.