The evidence is clear: Cervical cancer is best treated
with brachytherapy, a form of radiation therapy.
«Intermediate risk prostate cancer may be well controlled
with brachytherapy alone.»
Not exact matches
«Contrary to expectations, the more aggressive, combined treatment did not result in superior cancer control rates at five years follow - up, indicating that men can achieve a similar survival benefit
with fewer late side effects through
brachytherapy alone.»
At two years after treatment, more than 57 percent of men who had normal sexual function prior to treatment reported poor sexual function after surgery, compared
with 27 percent who reported poor sexual function after external beam radiation, 34 percent after
brachytherapy, and 25 percent after active surveillance.
Presenting these results at the 3rd ESTRO Forum in Barcelona, Spain, today (Monday) Professor James Morris, from the Department of Radiation Oncology, Vancouver Cancer Centre, British Columbia Cancer Agency (BCCA), Vancouver, Canada, will say that the ASCENDE - RT1 trial is the first and only existing trial comparing low - dose - rate prostate
brachytherapy (LDR - PB) for the curative treatment of prostate cancer
with any other method of radiation therapy delivery.
The authors focused on men newly diagnosed
with localized (non-metastatic) prostate cancer in 1995 - 2011 and treated
with radical prostatectomy,
brachytherapy, radiation therapy, or primary androgen deprivation therapy (PADT).
Results from a randomised controlled trial to compare the use of permanent radioactive implants (
brachytherapy)
with dose - escalated external beam radiotherapy in patients
with prostate cancer show that the men who received
brachytherapy were twice as likely to be cancer - free five years later.
Brachytherapy is an extremely efficient and safe radiation oncology modality, and this trial shows that it can have a wider field of applicability than simply in very localised and low risk tumours when combined
with other techniques — in this case, androgen deprivation therapy and external bean radiation therapy.»
A study by researchers at Brigham and Women's Hospital (BWH) found that
brachytherapy treatment was associated
with better cause - specific survival and overall survival in women
with cervical cancer.
The six benchmarks are: 1) HDR
brachytherapy procedures are supported with the appropriate team as described in the report of the AAPM TG 59 and the American College of Radiology HDR Brachytherapy Practice Standard; 2) commissioning of the treatment unit, treatment planning system and each new source is performed by a qualified medical physicist and verified through a QA process; 3) assay of the HDR brachytherapy unit source is performed using a well - type ionization chamber with a calibration traceable to the National Institute of Standards and Technology, and this assay is performed or confirmed for each s
brachytherapy procedures are supported
with the appropriate team as described in the report of the AAPM TG 59 and the American College of Radiology HDR
Brachytherapy Practice Standard; 2) commissioning of the treatment unit, treatment planning system and each new source is performed by a qualified medical physicist and verified through a QA process; 3) assay of the HDR brachytherapy unit source is performed using a well - type ionization chamber with a calibration traceable to the National Institute of Standards and Technology, and this assay is performed or confirmed for each s
Brachytherapy Practice Standard; 2) commissioning of the treatment unit, treatment planning system and each new source is performed by a qualified medical physicist and verified through a QA process; 3) assay of the HDR
brachytherapy unit source is performed using a well - type ionization chamber with a calibration traceable to the National Institute of Standards and Technology, and this assay is performed or confirmed for each s
brachytherapy unit source is performed using a well - type ionization chamber
with a calibration traceable to the National Institute of Standards and Technology, and this assay is performed or confirmed for each source change.
Factors associated
with higher odds of
brachytherapy use included younger age, being married, earlier years of diagnosis, earlier stage and certain SEER regions.
«A decline in
brachytherapy utilization is associated
with a higher rate of mortality in cervical cancer, so there's a direct relationship.»
The white paper recommends that practitioners follow relevant guidance documents and that deviation from consensus recommendations should be supported by clinical studies or pursued in the setting of a clinical trial approved by an institutional review board; that practitioners receive training in a new procedure before beginning its practice, that the training should include a practical, «hands - on» component and that all team members directly involved
with the radiation therapy decisions should participate in at least five proctored cases before performing similar procedures independently; and that professional societies should accelerate the generation of new or updated guidance documents for the following disease sites and techniques: skin, central nervous system, gastrointestinal, lung or endobronchial and esophagus, and, while outside the charge of this panel, assess the need for updated guidance documents for accelerated partial breast irradiation using electronic
brachytherapy.
In terms of patient survival,
brachytherapy was associated
with a higher four - year cause - specific survival (64.3 percent vs. 51.5 percent) and overall survival (58.2 percent vs. 46.2 percent) compared to EBRT alone.
Of the 7,359 patients identified, the researchers found that 63 percent of these women received
brachytherapy in combination
with EBRT, and 37 percent received EBRT alone.
Commissioned by ASTRO's Board of Directors as part of the Target Safely campaign, the white paper evaluates the current safety and practice guidance for HDR
brachytherapy, makes recommendations for guidance applications to the delivery of HDR
brachytherapy, suggests topics where additional guidance is needed and examines the adequacy of general physics, quality assurance (QA) and clinical guidance currently available for the most common treatment sites
with regard to patient safety.
«High - quality
brachytherapy must continue to be used, ideally
with image - guidance, to maximize survival and minimize toxicity.»
The standard treatment of locally advanced cervical cancer is EBRT
with concurrent chemotherapy, followed by
brachytherapy.
The department maintains seven linear accelerators, a dedicated TBI system, a CT image - guided
brachytherapy suite, an advanced multimodality image - guided operating (AMIGO) suite in collaboration
with Interventional Radiology, and a dedicated stereotactic linear accelerator.
Working together
with a multidisciplinary team of cancer specialists, our department uses highly advanced cancer care techniques including multimodality imagaing for defining tumor volume, state - of - the - art intensity modulated radiation therapy (IMRT), MRI - based treatment planning, and interstitial
brachytherapy using high dosage rate treatment.
Dose Modification Factor Analysis of Multi-Lumen
Brachytherapy Applicator
with Monte Carlo Simulation
First Study of Its Kind Depicts Benefits of
Brachytherapy for Patients
with recurrent Prostate Cancer after EBRT Read more
Usual treatment of patients
with stage lA2 and lB1 lesions consists of either radical hysterectomy
with bilateral pelvic lymph node dissection or radiation therapy (RT), which combines two kinds of therapy — whole pelvic teletherapy and local
brachytherapy (implants).