Sentences with phrase «with cell growth»

Tumour cells are «glutamine - addicted» [1,2] because glutamine is coupled to mechanistic target of rapamycin (mTOR) signalling, which integrates signals from growth factors, energy status and amino acid nutrition and co-ordinates these signals with cell growth, cell cycle progression and antioxidant machinery [3].

AMPK responds to energy deficits in the cell by down - regulating energy consuming processes, which are often associated with cell growth, and up - regulating energy producing processes.

Not exact matches

To read his blog is to watch the growth of a human being: You see Ev nearly lose his company, bring it back from the dead, strike it big, struggle with the tech support for his new cell phone, and get married.

The caption doesn't reveal any specific diagnosis, but it looks a lot like an epidermoid cyst — a common, usually benign growth filled with wet skin cells, as Lee has explained in previous videos.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Some reports, such as the Open Philanthropy Project's Animal Product Alternatives report and Van der Weele & Tramper (2014) suggest it is unlikely that cultured meats will become cost - competitive with conventional meat.98, 99 One important contributing factor in this conclusion, which is cited in these reports, is the minimum costs of the growth medium necessary for culturing the desired cells.

As a cancer researcher, do you think the mechanisms of tumor growth are somehow changing to come into line with your perceptions, or is it possible that the process of our learning more about DNA mutations and cell architecture and nutrient exchange and epigenetic effects make it possible for us to inch ever closer to understanding that which is already going on under our noses?

«We die daily»: so it is often said, not only with reference to the death of our bodily cells and their replacement by other cells every few years, but also in respect to our possible human growth.

We anticipate some sort of growth toward increased complexity: increasingly larger organic macromolecules, then the convergence of many macromolecules to constitute a simple living system, either as a cell with its protective wall and vital nucleus or as some functional analogue, then the convergence of many cells to form larger organisms.

Heretofore, this earth has witnessed the emergence of single - celled living organisms, the growth of multicelled plant organisms, the advent of animals with centralized nervous systems making self - directed activity possible, and the flowering of humanity with its far - flung culture.

Although this protein doesn't contain all the essential amino acids, it does contribute to your total daily protein intake to help with cell repair and growth.

Also, mushrooms are a great antioxidant and is filled with vitamin D, which helps inhibit the growth of cancer cells.

This is a quote that my nutrition teacher shared with the class and it helps to explain what I am saying: «The cause of nutrition and growth resides not in the organism as a whole but in the separate elementary parts — the cells.»

They found that epigallocatechin gallate, or EGCg, which is found in all tea, inhibits the activity of tNOX, an overactive enzyme that interferes with a cell's divide - and - rest cycle, and can facilitate uninterrupted growth of cancerous cells when combined with other factors.

Mogroside V has been found in research to have the ability to inhibit tumor growth in pancreatic cancer by interfering with the rapid dividing of cancer cells, preventing angiogenesis (blood flow to the tumor), and even promoting cancer cell death (10).

As well as containing vitamins and minerals its abundant with polyphenol antioxidants which help protect against cancer, one polyphenol in particular can slow or halt the growth of cancer cells!

Hindmilk, on the other hand, is the creamy milk with higher fat content that is stored in the milk - making cells located higher up in the breast, and helps stimulate your baby's growth.

Also functions as a hormone with roles in immune system health, insulin production, and regulation of cell growth.

In the new study, the scientists expressed surprise that the early abnormal growth of brain cells they observed in the fish embryo specifically affected male hormones, potentially indicating why more boys than girls are diagnosed with certain neurodevelopmental disorders such as autism.

Contributes to cell growth & regeneration of collagen when taken with iron and copper.

Its particular composition «nutrients with optimal bioavailability, hormonal and enzymatic components, anti-infective, trophic and growth factors, prebiotics and probiotics, biologically active molecules and cells» makes HM uniquely suited not only for term but also for preterm infants.

ZO ® OSSENTIAL ® GROWTH FACTOR SERUM PLUS is an anti-aging serum with ingredients such as synthetic snake venom neuropeptide, retinol, proteins, antioxidants, plant stem cells, and herbal extracts.

Muotri has found that a growth factor called IGF1 can prompt mini-brains derived from cells from children with Rett syndrome to make extra neural connections.

The phase 3 study, published online in The Lancet, is the latest to show the effectiveness of everolimus in slowing the cell growth that is overactive in patients with TSC.

The team at the Institute, supported by GSK and together with AstraZeneca have identified another way that PTEN may prevent uncontrolled cell growth.

Live cells can be monitored with the time - lapse function or the growth monitor.

«While environmental enrichment didn't seem to significantly influence the number of neurons [that were damaged],» explains Tsai, «it does induce the growth of dendrites and high numbers of synapses,» both of which are neuronal structures that underlie how brain cells communicate with one another.

A recent American Journal of Botany paper explains that conventional trees experience a secondary growth phase — replacing functional tissues with younger cells — but palm trees do not.

To guide ECM growth in particular alignments, the researchers used molds with very specific shapes, often constrained by pegs the cells had to grow around.

The cells, which lined the pores of the scaffold, were regularly fed with streams of nutrients, growth factors and oxygen in a bioreactor.

The mice were also injected with a dye that could illuminate the footprints of new nerve cell growth in the brain.

They have ready access to the bloodstream, which nurtures new cells with nutrients as well as hormones and signaling agents needed for growth.

In the placenta, RDGs have been found working in pathways associated with many of the tools of invasion: immune suppression, blood vessel growth, cell proliferation, and inflammation.

Small populations of adult stem cells with somewhat limited developmental potential are responsible for the body's ability to heal injuries and replace worn out cells and tissues, and evidence is growing that rare cancer stem cells are responsible for the uncontrolled growth of some malignant tumors, including glioblastoma.

The result fit with prior research indicating that accelerated growth of new brain cells in the dentate gyrus, in a process called neurogenesis, is necessary for antidepressants to cure rats of their depression.

Metastatic melanoma is the deadliest of the skin cancers and the mechanisms that govern early metastatic growth and interactions of metastatic cells with the brain microenvironment remain shrouded in mystery.

The current paper shows that treating with retinoids simultaneously with anti-estrogen therapies may pull cofactors for progesterone receptors away from their posts, disallowing their ability to open DNA at the point of CK5 and keeping the growth of dangerous CK5 + cells in check.

What they discovered was that an inflammatory factor known as TGF - beta (transforming growth factor - beta) can give cancer cells properties of immune cells by supplying the surface of the cancer cell with a receptor that normally only exists on the white blood cells that travel through the lymphatic system.

Meanwhile, recent human studies indicate that aging is associated with an increase in somatic mutations in the hematopoietic system, which gives rise to blood cells; these mutations provide a competitive growth advantage to the mutant hematopoietic cells, allowing for their clonal expansion — a process that has been shown to be associated with a greater incidence of atherosclerosis, though specifically how remains unclear.

A blood cancer characterized by the rapid growth of abnormal white blood cells, AML is typically treated with chemotherapy, in some cases followed by a stem cell transplant.

To find it, the scientists injected the eight tumor - bearing mice with high levels of labeled glutamine and glucose, another metabolic compound commonly linked to the growth of pancreatic cancer cells.

In mice, the Runx2 knock - in myeloma cells produced greater tumor growth and a wider spread of disease compared with the original myeloma cells; conversely, the Runx2 knock - down cells had less tumor growth and disease spread.

A mechanical strain - dependent cell wall growth rate predicted a straightening rate consistent with what was found experimentally.

When chlorotoxin is tagged with a fluorescent dye, it will illuminate a tumour — a trick that makes the surgeon's job easier by helping to pinpoint cancerous growth and ensure that all the cancerous cells are removed and healthy tissue spared.

Combining a new hydrogel material with a protein that boosts blood vessel growth could improve the success rate for transplanting insulin - producing islet cells into persons with type 1 diabetes.

In the present study conducted at IDOR in conjunction with UFRJ, the research team observed that ZIKV infects human - derived iPS neural cells, neurospheres and cerebral organoids causing cell death, malformations and reducing growth by 40 %.

«We showed that the coupling of cell wall growth to mechanical strain is quantitatively consistent with how bacteria recovered their shape after being deformed in experiments.»

And she had to work with bone cells to see how they would react to contact with the material and to determine what level of microvibration would best stimulate cell growth.

A team at Emory University is embedding electrodes in glass cones filled with nerve - growth factors that encourage brain cells to sprout more dendrites and axons.

To do so they focused on keratinocytes, a specific type of skin cells with a key role in psoriasis because of their abnormal growth and ability to produce large amounts of inflammation promoting factors.