Sentences with phrase «with cell migration»

The entire intestinal epithelium is renewed every week due to cell division in the crypts coupled with cell migration towards the villi and loss of cells by apoptosis at the tip of villi (Fig. 1A).

This study, published in the journal Microarrays, shows that lack of SOST in the bone microenvironment promotes the expression of many genes associated with cell migration and / or invasion, including long non-coding RNA MALAT1 in prostate cancer, suggesting that SOST has an inhibitory effect on prostate cancer invasion.

Not exact matches

Adding two blood - borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.

Consistent with previous findings, Apc suppression in the animals activated the Wnt signaling pathway, which is known to control cell proliferation, migration, and survival.

In a new study, NAIST scientists, in collaboration with researchers at the Osaka National Hospital and University of Tokyo, report that the L1 Cell Adhesion Molecule (L1 - CAM) is crucial for directed axon migration.

The research team tested the cells in dishes that were treated with luteolin and found that migration was inhibited by the plant compound.

The team is also planning further research to find out more about why pancreatic cancer cells rely on PAK4 and what other proteins and pathways PAK4 is interacting with to drive cell growth and migration.

They are associated with the cell cytoskeleton — a complex network of interlinking filaments inside the cell that is necessary for cell migration — making them viable targets for inhibiting migration.

A study by Sofia J. Araújo, a Ramón y Cajal researcher with the Morphogenesis in Drosophila lab at the Institute for Research in Biomedicine (IRB), elucidates the genetic regulation of cell migration.

The team from the Massachusetts General Hospital plans to use the microfluidic devices in synergy with some more sophisticated molecular biology tools and identify the control factors of cell migration speed.

Classical cell migration experiments use uniformly coated glass plates with the drawback that cells adhere very strongly to the glass surface and move randomly in any direction.

In addition, cells were stimulated with a growth factor (PDGF) which led to fast cell migration in only one direction lasting for many hours.

Mutations of RGS1 are associated with several autoimmune diseases, including multiple sclerosis, and a drug targeting cell migration has been approved to treat multiple sclerosis, he notes.

«In this study, we found that enhanced neuropilin - 1 (NRP - 1) and NEDD9 levels in endometrial and lung cancer positively correlated with metastasis, while liver kinase B1 (LKB1) inhibited the migration of cancer cells.»

In particular, the research identified several genes regulated by methylation in the egg that are involved in cell adhesion and migration — both vital properties for cells of the developing placenta in establishing connections with maternal tissues to support embryo development.

The laboratory is working in collaboration with Dr. Paula Foster to develop real - time cellular magnetic resonance imaging techniques as a means to track dendritic cell migration in vivo in humans.

Zhang, X, de Chickera, S.N., Willert, C., Economopoulos, V., Noad, J., Rohani, R., Wang, A.Y., Leving, M.K., Scheid, E., Foley, R., Foster, P.J. and Dekaban, G.A. Non-invasive detection of the in vivo migration of human monocyte - derived dendritic cells into the popliteal lymph nodes of CB17 / scid mouse with cellular MRI.

MicroRNA - 24 inhibits the proliferation and migration of endothelial cells in patients with atherosclerosis by targeting importin - a3 and regulating inflammatory responses.

The expression of the proprotein convertase furin is strongly associated with increased metastasis (migration) of cancer cells; this is thought to be due to its ability to activate the cell surface enzymes responsible for extracellular matrix breakdown.

Nck enables directional cell migration through the coordination of polarized membrane protrusion with adhesion dynamics.

She has worked in prestigious Institutions like the NIH - NCI, Bethesda, Md and the MIT, Cambridge, MA and developed an internationally recognised research profile in tumour cell migration and invasion with over 65 publications and 2 patents to her name.

Laminin - 521 induce fast migration of the cells and laminin isoform specific activation of PI3K / Akt pathway through interaction with α6β1 integrin.

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion.

Structural analogues with similar binding properties may also be active against HIV infection, cancer cell migration, and inflammatory disorders mediated by CXCR4.

Adhesion with HA plays an important role in cell migration and tumor growth.

Cancer cells in intravital mouse models and in vitro display many «modes» of migration, from single isolated cells with round or elongated phenotypes to loosely - / non-adherent «streams» of cells or collective migration of cell strands and sheets.

We found that the V+S + population expressed sets of genes that fell into major functional categories that were associated with «Cell adhesion» and «Cell migration.»

Importantly, spreading and migration do not occur with cells expressing NG2 variants lacking the cytoplasmic domain of the proteoglycan, suggesting that interaction of NG2 with cytoplasmic ligands is required for these processes to take place.

Metastasis begins with the invasion of tumor cells into the stroma and migration toward the blood stream.

We show for the first time that kahweol is an anti-angiogenic compound with inhibitory effects in two in vivo and one ex vivo angiogenesis models, with effects on specific steps of the angiogenic process: endothelial cell proliferation, migration, invasion and tube formation on Matrigel.

The broad objective of our research is to understand how epithelial cells interact with their microenvironment during migration, focusing on the mechanism of cell migration and the role of actin cytoskeleton in this process.

We showed that WDR47 shares functional characteristics with LIS1 and participates in key microtubule - mediated processes, including neural stem cell proliferation, radial migration, and growth cone dynamics.

(A) Treatment of MDA - MB - 231 cells with 0.3 μM flavopiridol (Flvp) significantly impairs cell migration as shown by the Transwell assay.

After eGFP - expressing CD4 + T cells and WT counterparts were treated with vehicle and indicated inhibitors, respectively, they were mixed with the collagen gel and monitored for cell migration.

A «WOW» maple syrup finding: Take this 2015 study reported in Oncology Reports: the researchers examined the effect of three grades of maple syrup (grades are based on the color of the syrup and ranges from light to darker with color being influenced by time of year and processing technique) on the proliferation, migration, and invasion of colorectal cancer (CRC) cells in order to investigate whether maple syrup is suitable as a phytomedicine for cancer treatment.

And with widenning of the Hadley cell extent, would the seasonal migration of the ITCZ also increase (and is that related to any changes in variability)?

Obviously, we are currently in transition and our global atmospheric cell structures are going to shift rapidly with broadly expanding Hadley cell and collapsing Arctic cell leading to meridional migration of average cloud cover and reduced albedo.