Sentences with phrase «with cell samples»

Some researchers work with cell samples in vitro; some do pre-clinical work in mice and rats.

Not exact matches

«Eben came into the class with a sample of agricultural waste and mushroom cells and asked me what I thought,» he recalls.

The third order (lower scale) is common for these 2 dosing and high - multiple blood - sampling days (days 1 and 8), with each cell on the time axis representing 1 h.

Calls were made to a stratified weighted sample of voters from the L - 2 Voter list via both land and cell phones, supplemented with additional cell phone sample from Survey Sampling International

For the cell sample, interviews were conducted with the person who answered the phone.

«The new Park Nanoscience Center at SUNY Polytechnic Institute provides researchers with greater access to Park Systems» cutting - edge AFM nanoscopic tools, featuring reliable and repeatable high - resolution imaging of nanoscale cell structures in any environment without damage to the sample.»

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.

Many tumors release cells with distinctive antigens on their surfaces, and affinity - based techniques can pull these cells out of the blood sample relatively easily.

In collaboration with Anna Pyle, Howard Hughes Medical Institute investigator and professor in the Department of Molecular, Cellular and Developmental Biology at Yale, Patrizio and his team studied samples from 20 cumulus cells in 15 patients younger than age 35 and in those age 40 and older.

In cancer research, our goal is to be able to start with a sample of human tissue, extract many cells of interest, and perform genetic analysis upon each of them separately.

Analyzing a database of nearly 800 multiple myeloma patient samples, they discovered that 162 patients with low ADAR1 levels in their tumor cells survived significantly longer over a three - year period compared to 159 patients with high ADAR1 levels.

«The massive advantage with our stain-less laser - based imaging approaches is that you can use the stem cell sample without having to interrupt the developmental process in real time, you don't need to perform any cell disruption and there is no photobleaching (fading) which is fairly common with fluorescent material,» Catarina enthused.

But the samples he saw never contained intact organelles — specialized cell structures with dedicated jobs.

To address this gap in knowledge, Mirabello and Schiffman teamed up with co-senior author Robert Burk of Albert Einstein College of Medicine to sequence the whole genomes of 5,570 HPV16 - infected cell and tissue samples from women around the world and to identify associations between HPV16 genetic variants and the risk of cervical precancer and cancer.

Researchers used tissue and blood samples to show that the gammopathy (a precursor to myeloma) in both mice and patients with Gaucher disease is triggered by specific lipids, and that the antibodies made by tumor cells in nearly a third of myeloma patients are directed against such lipids.

Studying such diseases is a good first step because they are cancers of immune cells themselves, and it's possible to analyze them with a mere blood sample.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

Previously, high - resolution live imaging has been done with cells cultured on glass slides, which flattens samples.

What the rover can do is detect the building blocks for those cells with its portable chemistry lab, Sample Analysis at Mars.

He also recommends performing standard bulk - cell sequencing on a portion of the sample, to provide a basis for comparison with the single - cell DNA data.

The researchers tested samples of brain cells from people with MS and healthy control subjects and found evidence of the virus in the olfactory bulb in both groups.

If it proves positive, the researchers will mix another portion of the sample with cultured bat and monkey cells to test for active virus.

As other researchers asked for samples, the cells replicated, grew, and proliferated so wildly that they often took over and wiped out cell lines of any kind with which they happened to come in contact.

The finding, reported by a Stand Up to Cancer - Prostate Cancer Foundation Dream Team in the May 21 edition of the journal Cell, is based on an analysis of tumor samples from 150 men with metastatic prostate cancer that no longer responded to standard hormone - blocking therapy.

To date, much of the research on irradiation's effects on the cellular microenvironment has dealt with samples that included cells, obfuscating the irradiation's effect on just the ECM rather than the cell's internal machinery.

Spearheaded by first author Christopher McNair, PhD, a graduate student in the laboratory of Dr. Knudsen, the study undertook an extensive analysis of tumor samples and cell - free DNA samples from patients with advanced, lethal - stage prostate cancer.

By devising a dual - objective system with two microscope lenses facing each other, Xu and colleagues viewed the front and back of the sample at the same time and achieved unprecedented optical resolution (of approximately 10 nanometers) of a cell.

Tissue engineers have been unable to grow epidermis with the functional barrier needed for drug testing, and have been further limited in producing an in vitro (lab) model for large - scale drug screening by the number of cells that can be grown from a single skin biopsy sample.

In addition, the researchers looked at brain samples of deceased patients with MS and found increased numbers of GM - CSF - producing cells in comparison to normal brain samples.

They checked that the viral gene fragments in the child and mother were a close match, and double - checked that the samples of blood cells from the child were his and no one else's, by matching them genetically with the mother.

Sebetan, who presented the findings at the American Academy of Forensic Sciences meeting in New Orleans last week, was surprised that the control samples began with fewer live cells than the spermicidal condoms.

But with this technique, we can just take a small sample of non-muscle tissue, like skin or blood, revert the obtained cells to a pluripotent state, and eventually grow an endless amount of functioning muscle fibers to test.»

The team worked with samples of silicon, an n - doped semiconductor material that acts as a simple solar cell to produce a voltage when illuminated.

With a miniscule blood sample, the HemeChip, a micro-electrophoretic device, examines and identifies hemoglobins, including hemoglobinopathies sickle cell anemia (HbSS), sickle trait (HbAS) and SC disease (HbSC).

Freezing meat damages the cell walls so the mobility of any water molecules and the way in which they interact with the proteins in the sample changes after freezing.

The team started by analyzing bone marrow samples from children with B - ALL and cataloging every protein present in the leukemia cells.

Nana - Sinkam and his colleagues examined lung - tumor samples from 81 patients with stage - 1 nonsmall - cell lung cancer and tumor - cell lines.

A small skin sample from a person with bipolar disorder can yield stem cells that can be coaxed to become neurons just like those in the brain.

They treated a variety of healthy tissues and 23 samples of cancer cells taken from leukemia patients with AG1295, a drug known to selectively block the kinase.

Researchers have used radioimmunotherapy (RIT) to destroy remaining human immunodeficiency virus (HIV)- infected cells in the blood samples of patients treated with antiretroviral therapy, offering the promise of a strategy for curing HIV infection.

But about 20 years ago, researchers started noticing that the levels of cytokines and T - cells, which help drive immune responses and secrete cytokines, were higher instead of lower in blood samples from people diagnosed with depression.

The team compared a sample of fresh red blood cells with cells that looked spiky because their energy stores had been depleted.

Staining minute samples of sediment with a fluorescent dye that binds to DNA, he found he could count cells under his microscope, just as Boetius would do with her Hydrate Ridge samples many years later.

Dr. Islam saw this phenomenon occur in cell culture and in some samples from patients with head and neck cancers.

Researchers of KIT and the Center for Nanotechnology (CeNTech), Münster, have now developed a clinical method to reliably detect and isolate single cancer cells in blood samples in cooperation with the University Hospital of Hamburg - Eppendorf (UKE).

The research team with international collaborators analysed more than 100 patient samples from ovarian and other cancer types to discover a distinct population of cells found in some tumours.

Lanza previously led a clinical trial in the United States — published November 2014 in the Lancet — that demonstrated embryonic stem cells could be used safely for patients with degenerative eye diseases, but the patient sample was Caucasian with the exception of one African - American.

After a four - year experiment with two comparable 533 - tonne samples of municipal waste, the leachate from the wet cell contained dissolved organic particles from food, leaves and garden debris totalling 2700 milligrams per litre.

Toner pumped samples of whole blood through the channels, which were coated with an antibody designed to trap any cancer cell that carries a common surface protein, much as flypaper snags pesky insects.

The researchers identified the LSC17 score by sampling the leukemia stem cell properties of blood or bone marrow samples from 78 AML patients from the cancer centre combined with molecular profiling technology that measures gene expression.