Insulin assists
with cellular uptake of glucose from the bloodstream into the cells of the body for energy.
It was found that toxicity correlates with oxidative stress rather than
with cellular uptake.
Not exact matches
The team also showed that the
cellular process macropinocytosis, which participates in cell scavenging nutrients and vesicles, contributes to exosomes
uptake in cancer cells
with mutant KRAS.
To image glucose
uptake activity at the
cellular level, glucose analogues labeled
with fluorescent dyes have been developed.
After graduating, Clara moved to the UK to work as a Research fellow
with Prof John Findlay at the University of Leeds, working mainly
with Lipocalins and their
cellular receptors, identifying structural binding / transport motifs and investigating the physiological link between vitamin A
uptake and Type 2 Diabetes.
«That issue starts at the
cellular - molecular level,
with the actual testing and the understanding that biologists have of the pathology of colorectal cancer and diagnosis of colorectal cancer, all the way to the community
uptake of that screening.»
Functionalisation of silver nanoparticles
with monosaccharides modulates their
cellular uptake and toxicity.
Observed toxicity was strongly correlated
with intracellular oxidative stress, measured as protein carbonylation, but not to
cellular uptake.
Here, we discuss the toxicity and the
cellular uptake of different silver nanoparticles functionalized
with citrate, three different monosaccharides as well as ethylene glycol on two different cell lines.
Testosterone stimulates
cellular amino acid
uptake and protein synthesis in muscles by interacting
with the DNA, as well as increasing muscle fiber site neurotransmitters.
Twelve - hour exposure of 3T3 - L1 adipocytes to H (2) O (2) or TNF - alpha resulted in the increase of c - Jun NH (2)- terminal kinase (JNK) activation and insulin receptor substrate 1 (IRS1) serine 307 phosphorylation, concomitantly
with the decrease in insulin - stimulated IRS1 tyrosine phosphorylation and
cellular glucose
uptake.