Sentences with phrase «with changes in the expression»

Its appearance following starvation and other stresses is associated with changes in the expression of over 500 genes, most prominently genes for the structural RNAs that are components of the ribosome — the enzyme responsible for protein synthesis.

Not exact matches

And thank you America for the freedom of speech you granted the world and has provided us the utilities of communications asking us to contribute with our expressions towards» Change for the Good of ship and passengers on board» since there is no Ark better than earth to save us in this wide unpredictable space?!

But again, and even with the possible implication of divine judgment in the death of Rachel, we see the repeated motif of the Jacob cycle: the tension between sin and divine grace, the expression of faith that Jacob - Israel is saved and redeemed only by the will and purpose of God (35:5), and finally the repetition of the promise and the blessing, and the second account of the changing of Jacob's name to Israel.

The conference was spearheaded by Michael Davidson, a man of God who came out of the homosexual life many years ago and heads up a group called Core Issues Trust («a non-profit Christian ministry supporting men and women with homosexual issues who voluntarily seek change in sexual preference and expression») and by Andrea Williams, dynamic barrister and CEO of Christian Concern (an organization that seeks to be «a strong Christian voice in the public sphere») and the Christian Legal Centre (a legal defense team for British Christians persecuted for their faith).

The pastoral role is concerned with ministry to individuals; the priestly role has to do with the proclamation of the faith and with leadership in the liturgical life of the church; the prophetic role focuses on judging the level of humaneness in the social order and pointing to the changes required if common justice is to be approximated; the kingly role takes up governance and the expression of neighbor love through responsible corporate action.

When in 169 one of the contestants, Menelaus, was returned to the office, Antiochus, who had already incurred the bitter resentment of faithful Jews by his interference, sought to correct his financial plight by entering the Temple himself and stripping it of its considerable movable wealth.31 Antiochus became at once the object of Judaism's bitterest hate; and no doubt in part in retaliation but also as an expression of this ardent Hellenist's frustration with a people slow to change, he effected an otherwise quite unprovoked attack on Jerusalem in 168.

Men have tripped, gone down with a splash, and come up with hardly a change of expression to carry on the struggle; they have run along river banks, hurdling rocks and thrashing out into the water around log jams, in their effort to turn, control and finally dominate their trout.

I agree that ozil is probably one of the best crossers in europe but that being said he is also one of the best passers in europe, the best way to accomodate this is the way we did last season, make all the playmakers play with fluidity, ramsey / ozil / ox exc should be switching positions all game, to confuse the opposition, which we did so well in the first half of the season, if we can sustain that type of play whilst changing formations at the right time, there's no reason why we shouldn't have the title wrapped up by the time we get to Old Toilet, to see my good old mate Judas's facial expression when he has to congratulate our achievement

Learning how to use hand expression can help you become more comfortable with your breasts and more aware of what's normal and not normal, plus it could help you notice any changes in your breasts that need attention.

In addition to giving your partner a break, it's a chance for you and your baby to start practicing conversation skills by making eye contact, cooing noises and engaging your baby with changing facial expressions.

Folks, I watched the event on our TV station, TV3 with some colleagues in the office and some panel member including an NPP person (name withheld) and the moment the person realized Mac - Manu used his left hand to pick the paper, his facial expression and demeanor changed, indicating he was not in favour of Mac - Manu's actions.

They compared changes in gene expression in 37 of them who developed suicidal feelings with previously published work and with post-mortem samples of 26 men who had killed themselves.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

Prolonged oral administration of a pan-retinoic acid receptor antagonist inhibits spermatogenesis in mice with a rapid recovery and changes in the expression of influx and efflux transporters.

Scans showed remodeled DNA methylation patterns in the low - fat group, which changed gene expression associated with fat metabolism and inflammation in the liver; there was less fat accumulation and inflammation in the liver.

They found similar changes in gene expression in the same genes with increased activity of glucose transporters in both the stem cells and the fat cells, Sen noted.

The researchers demonstrated that blocking the PGD enzyme genetically or with a pharmacologic inhibitor reversed the epigenetic reprogramming and malignant gene expression changes detected in distant metastases, and also strongly inhibited their tumor - forming capacity, with no effect on normal cells or peritoneal pancreatic cancer controls.

While nicotine and non-nicotine products both produced changes, e-cigarette products without nicotine resulted in even more gene expression changes than products with nicotine, Zelikoff said.

Still, he says it would be «reassuring» to see the study repeated with more subjects, and he notes that the work leaves unanswered which comes first, the loneliness or the change in gene expression.

In collaboration with Yi Xing from UCLA, the team catalogued and analyzed how gene expression patterns in skin cells differed among the Esrp knockouts and found hundreds of significant changeIn collaboration with Yi Xing from UCLA, the team catalogued and analyzed how gene expression patterns in skin cells differed among the Esrp knockouts and found hundreds of significant changein skin cells differed among the Esrp knockouts and found hundreds of significant changes.

Further study showed that the region of human DNA that contained the single nucleotide change associated with blondness specifically affected the expression of KITLG only in hair follicles.

When his team looked at gene expression changes in the mice, then applied them to humans with early stage cancer, the results revealed a breakdown of which patients have a high or low chance of survival.

The axiom, «growing like a weed,» takes on new meaning in light of changes in gene expression that occur when weeds interact with the crops they infest, according to plant scientist Sharon Clay.

«There are genes and proteins that are expressed in a cell and their activity, or expression level, changes with time of day,» explained St. John.

Further studies discovered that the BRAF protein could turn on many itch genes, and they showed similar changes of gene expression in mice with chronic itch induced by dry skin and in mice with allergic contact dermatitis, two of the skin conditions that frequently cause people to scratch incessantly.

But the researchers found no significant changes in the expression of genes known to be involved in calcification from prior studies comparing strains with dramatically different calcification levels.

The genomics era has had a profound impact on life science research, leading to significant developments such as the use of expression quantitative trait loci (eQTLs), which link polymorphisms in single genes to quantifiable changes in gene expression associated with specific diseases.

A case in point are two freezers packed with more than 2,000 Arabidopsis seedlings awaiting return to Earth, where they can be analyzed for changes in gene expression.

This altered expression that does not correlate with changes in the base sequence is known as epigenetic regulation (as opposed to genetic regulation).

Surprisingly, more than 80 percent of the dependencies with biomarkers were associated with changes (up or down) in a gene's expression.

«Within 3 weeks after expression of the NeuroD1 protein, we saw in the microscope that human glial cells were reinventing themselves: they changed their shape from flat sheet - like glial cells into normal - looking neurons with axon and dendritic branches,» Chen said.

Using this approach, these investigators found that nodes (genes) with high connectivity tend to have lower levels of change in expression than peripheral nodes, consistent with the notion that disease ‐ causing genes are typically not central hubs in a molecular module.

The most significant changes occurred in a gene called RbAp48, whose expression declined steadily with aging across the study subjects.

Circadian genes turned out to be also infradian genes, whose expressions go up and down with mood - change - like behaviors in these mice,» Miyakawa explains.

Sanny S. W. Chung, Xiangyuan Wang, Debra J. Wolgemuth; Prolonged Oral Administration of a Pan-Retinoic Acid Receptor Antagonist Inhibits Spermatogenesis in Mice With a Rapid Recovery and Changes in the Expression of Influx and Efflux Transporters, Endocrinology, Volume 157, Issue 4, 1 April 2016, Pages 1601 — 1612, https://doi.org/10.1210/en.2015-1675

Mycoplasma compete with host cells for nutrients and can alter expression of receptors, ion channels, and growth factors resulting in changes to the cell line's growth and behavior.

He studies how structural changes to chromosomes impact gene expression and cell fate with a focus telomere, telomerase, and chromosomal stability, epigenetic proteins, and the role of the SOSS complex in DNA damage repair.

• CpG methylation status quantification PyroMark ID provides highly reproducible quantification of methylation frequencies in individual consecutive CpG sites, enabling accurate measurement of even small changes in methylation levels that are associated with deregulation of gene expression and tumorigenesis.

Changes in replication, nuclear location, and expression of the Igh locus after fusion of a Pre-B cell line with a T cell line.

Genetic data combined with information on gene expression and epigenomics in relevant tissues, and clinical information, can provide clues about the effects of genetic changes within an individual's genome that increase or decrease one's risk of developing type 2 diabetes and its complications, including heart and kidney disease.

With the reference cell census data in hand, the research team is excited to conduct additional studies, including ones involving models or human patients with gastrointestinal conditions — Crohn's disease, ulcerative colitis, gastrointestinal cancers, forms of food allergy, etc. — aimed at identifying changes in gene expression and epithelial structure and function that could reveal new insights and opportunities for therapeutic developmWith the reference cell census data in hand, the research team is excited to conduct additional studies, including ones involving models or human patients with gastrointestinal conditions — Crohn's disease, ulcerative colitis, gastrointestinal cancers, forms of food allergy, etc. — aimed at identifying changes in gene expression and epithelial structure and function that could reveal new insights and opportunities for therapeutic developmwith gastrointestinal conditions — Crohn's disease, ulcerative colitis, gastrointestinal cancers, forms of food allergy, etc. — aimed at identifying changes in gene expression and epithelial structure and function that could reveal new insights and opportunities for therapeutic development.

We use extensive genomic and gene - expression profiling techniques to identify molecules and molecular pathways that mediate the dynamic changes observed in vitro, and which are associated with different clinical outcomes in melanoma patients.

c Heatmap with normalized expression values for genes with changes in liver.

The majority of the changes in gene expression, however, occur between 7 and 14 h post-death, with thousands of genes showing differential expression (equally in both directions) relative to pre-mortem samples.

He is also participating in a project in collaboration with the laboratory of Dr. Kate Fitzgerald (UMass Medical School) to analyze expression changes of long non-coding RNAs (lncRNAs) during Dengue virus infection in dendritic cells.

While there are noticeable changes in gene expression associated with PMI, we nonetheless found that the characteristic transcriptional signature of tissues remains largely intact through the PMI intervals considered here.

The relative quantification (RQ) value reflects the fold changes of mRNA expression in each cell line compared with the parental cell lines.

We observed that in the majority of tissues there are many genes that display expression profiles that are more complex than simple monotonic changes with PMI.

The RQ value reflects the fold changes of miRNA expression in each cell line compared with the parental cell lines.

Other genes such as the chemokine CXCL2 show a more dynamic behavior with expression changes in opposite directions at subsequent intervals (Fig. 2d).