Sentences with phrase «with cholesterol synthesis»

``... several animal studies indicate serious health risks associated with GM food consumption including infertility, immune dysregulation, accelerated aging, dysregulation of genes associated with cholesterol synthesis, insulin regulation, cell signaling, and protein formation, and changes in the liver, kidney, spleen and gastrointestinal system.»

Not exact matches

Kahn and his team suspected that reduced cholesterol synthesis interferes with brain synapses.

Despite this possibility, mevinolin, the active ingredient in red yeast rice, is capable of reducing 7 - dehydrocholesterol levels, 22 and simvistatin (Zocor) not only inhibits the synthesis of mevalonate but also enhances the conversion of 7 - dehydrocholesterol to cholesterol by increasing the expression of 7 - DHCR.23 Simvistatin thereby hits the pool of 7 - dehydrocholesterol with a double - whammy, both decreasing its synthesis and increasing its degradation.

Cholesterol - lowering statin drugs could theoretically interfere with the synthesis or functioning of the vitamin D - binding protein (DBP).

Increased enterohepatic circulation on high fat means that cholesterol is kept «in play» - bounced back into the bloodstream in ApoB particles - while low enterohepatic circulation, in people with with higher synthesis rates, during weight loss - when cholesterol is being dumped by shrinking cells - means that cholesterol can pile up in the gall bladder faster than it can be conjugated to bile salts and bile acids and faster than it can be extracted by the weak stimulus of low fat food.

Hi George, Seems like i belong to the first type «One type featured high rates of cholesterol (re) absorption with low rates of cellular cholesterol synthesis.

One type featured high rates of cholesterol (re) absorption with low rates of cellular cholesterol synthesis.

The other type featured low rates of cholesterol (re) absorption and high rates of intracellular cholesterol synthesis, associated with low HDL, high event rates, and a significant benefit of statin treatment, which lowered event rates to those of the first group on or off statin.

This complex synthesis involves 37 steps and starts with a key enzyme known as HMG - CoA reductase (inhibited by statins, a class of cholesterol - lowering drugs).

CoQ10 deficiency can result from deficiency of any of the seven vitamins required for its synthesis, or by interference with its synthesis by cholesterol - lowering drugs or hormone replacement therapy (HRT).

Any pharmaceutically - induced disruption in endogenous synthesis of cholesterol — especially when combined with long - standing, population - wide recommendations to limit dietary intake — would starve the struggling brain of this absolutely critical nutrient.

For example the most powerful increaser of total cholesterol is probably lauric acid, but lauric acid is also the most powerful reducer of the LDL - to - HDL - cholesterol ratio — this is consistent with lauric acid being burned for quick energy, thus increasing the energy state of the liver cell and allowing for greater cholesterol synthesis.

In the case of heart disease, recent research has shown that pear fibers are able to bind together with bile acids in the intestine, lowering the pool of bile acids and decreasing the synthesis of cholesterol.

Thus it makes sense, and helps to keep cholesterol in balance with requirements, that cholesterol synthesis is stimulated by insulin (the fed state hormone) and inhibited by glucagon (the fasting state hormone).

A reduction in dietary carbohydrate will have the opposite effect and this, coupled with the additional inhibition by dietary cholesterol and fats on endogenous synthesis, is likely to be the mechanism via which physiological ketosis can improve lipid profiles.

Viscous fibers may interfere with the absorption and enterohepatic recirculation of bile acids and cholesterol in the intestine, forcing the liver to synthesize more cholesterol to meet the need for bile acid synthesis, and thus decreasing circulating cholesterol.