Sentences with phrase «with circulating tumor cells»

In addition, while cfDNA correlated with tumor metabolism, no association was found with circulating tumor cells (CTCs).

«We wanted to utilize platelets» intrinsic tendencies to accumulate at wounds and to interact with circulating tumor cells, for targeted delivery of immune checkpoint inhibitors» said Gu, «Interestingly, we found the antibody can be promoted to release from activated platelets in the surgical site, due to generation of small platelet - derived microparticles upon the platelet activation.

Not exact matches

Chicago, GenomeWeb — A new study by researchers from Memorial Sloan Kettering Cancer Center has demonstrated the predictive power of an AR - V7 protein expression test using Epic Sciences» non-EPCAM-based circulating tumor cell detection platform, which could help guide treatment decisions for men with metastatic castration - resistant prostate cancer.

The other two major targets in the field, circulating tumor cells and exosomes, come with their own challenges.

Shown here is a cluster of circulating tumor cells (red) from a patient with breast cancer.

Now a team of researchers in China has developed a new microfluidic chip that can quickly and efficiently segregate and capture live circulating tumor cells (CTCs) from a patient's blood, with potential applications for cancer screenings and treatment assessments.

Among patients with non-small cell lung cancer (NSCLC) fueled by ALK gene alterations who were being treated with crizotinib (Xalkori), a decrease in the number of circulating tumor cells (CTCs) harboring increased copies of the ALK gene over the first two months of treatment was associated with increased progression - free survival.

In a study presented in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount of cell - free tumor DNA circulating in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the body).

The size difference between tumor and healthy circulating DNA was initially discovered in animal tumor models created by inducing tumors with human cancer cells.

Epidermal growth factor receptor (EGFR) mutations found in the circulating free tumor DNA (ctDNA) from the plasma of advanced non-small cell lung cancer (NSCLC) patients correlates well with the EGFR mutations from patient - matched tumor tissue DNA.

Currently, in another study, the researchers are focused on detecting circulating tumor cells in the blood of patients with a diagnosis of breast cancer.

Adds Liu: «With metastatic cancers accounting for around 90 % of deaths from solid tumors, the hope is that one day a device that can enable the analysis of single tumor cells circulating in the blood could make a big difference in early diagnosis, detection and monitoring of numerous types of cancer, without invasive biopsies.»

The role of rebiopsy and repeat analysis in the setting of post-treatment relapse, along with testing of blood samples for mutations in circulating tumor cells, cell free tumor DNA, or exosomes will be considered.

To better study circulating tumor cells, the researchers collaborated with physician - scientists and industry engineers to develop a microfluidics system that separates these large cells into a concentrated sample.

«Circulating tumor cells — cells from a tumor that have escaped into the bloodstream with the potential to spread into other tissues — are extremely useful for assessing a patient's disease in order to select the most appropriate treatment,» said UBC mechanical engineering professor Hongshen Ma, the lead researcher.

The authors also show that mice with tumors show an increase in the number of this type of circulating progenitor cells.

He noted that there are some ongoing studies that may further inform this difference in the future, including tumor DNA analysis with whole exome sequencing and tumor RNA analysis with RNAseq, evaluation of circulating cell - free tumor DNA, and hypermethylation.

Blood Biomarkers Identified in Drug - Resistant Cancer Tumor Cells November 2016 While searching for a non-invasive way to detect prostate cancer cells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated wiCells November 2016 While searching for a non-invasive way to detect prostate cancer cells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated wicells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated with...

A technique already developed by Dr. Simeone's research team, in collaboration with Dr. Sunitha Nagrath, for isolating circulating tumor cells was the foundation for this novel approach to personalized therapeutics.

Immunicon Corporation (PI)($ 40,000 Total) 2001 - 2002 Longitudinal enumeration of circulating tumor cells in patients with metastatic breast carcinoma

The herringbone pattern of interior surfaces in the HB - Chip brings more circulating tumor cells into contact with the antibody - coated capture surfaces.

It can help reduce the size of a solid tumor (lymphosarcoma) and decrease the number of circulating cancerous cells in a cat with leukemia.