Sentences with phrase «with clinical applications»

Topics: Ultrasound / sonographic pathology with clinical applications, interventional ultrasound, melding the medicine with the sonogram.

In future studies, Sulchek and his team plan to test this approach and scale up the technology with clinical applications in mind.

In the field of iPS cell - based regenerative medicine, advanced research with clinical applications for many organs and tissues, such as the retina, has steadily progressed.

Another field that might appeal to your desire to work in a role with clinical applications is that of clinical trials.

At the dawn of the digital health revolution, some argued that fitness trackers were being marketed as a way for companies with long - range ambitions to produce devices with clinical applications to get to revenue in the short - term.

Worked with each clinical application security lead to coordinate and implement the requested recommendations.

Not exact matches

When does the amount of automated «clinical thinking» done by the software application constitute the «practice of medicine» with all its associated ethical and legal aspects?

The combo proved non-inferior to competing HIV medicines in a slew of late - stage clinical trials, and Gilead is expected to file a new drug application with the FDA soon.

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

And as investors and companies gain experience working with clinical, regulated applications, such deals should also become more common as well.

In this randomized, double - blind clinical trial, virgin coconut oil was the clear winner: «among pediatric patients with mild to moderate AD, topical application of virgin coconut oil for eight weeks was superior to that of mineral oil based on clinical (SCORAD) and instrumental (TEWL, skin capacitance) assessments.»

In her 24 years of clinical work with children, adolescents, and young adults, she has emphasized the critical importance of integrating neuropsychological assessment findings to the application of accommodations to the classroom and home environments in a «user - friendly» manner.

Virtual reality has emerged into popular culture with an ever - widening array of applications including clinical use in a pediatric healthcare center.

But in order to find the right «fit» for you, we need to consider your wish to work more closely with people, both in terms of personal contact and clinical application.

Applicants can have either research or clinical backgrounds, with applications encouraged from scientists seeking to return to their home countries.

Outcomes of children and young adults with cancer have improved, primarily due to enhanced understanding of tumor biology and due to the clinical application of biological discoveries through multicenter clinical trials.

«Consequently, clinical application of these materials has been limited due to cultural and religious restrictions associated with these mammalian tissue - derived materials.

One of the study's clinical investigators, Dr Eric Widra from Shady Grove Fertility in Washington DC, USA, acknowledged that interest in a freeze - all approach to IVF is growing, but not yet with broad application.

«Ultimately, our aim is to create these with the goal of finding clinical applications,» Lieber said.

Crucial research breakthroughs often lack direct clinical applications themselves but are essential for future discoveries with direct applications.

With more research, we hope to get closer to clinical and therapeutic applications.»

Her current research focuses on developing clinical applications for imaging flow cytometry, with special attention to transcription factor pathways.

He moderated a premeeting session where scientists discussed advances with officials of the U.S. Food and Drug Administration, which would review any application for a clinical trial.

The clinical application of this technology is clear, says lead author Emre Ozkumur, a biomedical engineer also at Massachusetts General Hospital who developed the system with Toner.

However, in a clinical setting, you can take a regular ultrasound machine and equip it with a light source — you can buy LEDs for around $ 200 that are powerful enough and safe for clinical applications,» Chan said.

An international group of 11 organizations with genetics expertise has issued a policy statement on germline genome editing in humans, which recommends against genome editing that culminates in human pregnancy; supports publicly funded, in vitro research into its potential clinical applications; and outlines scientific and societal steps necessary before implementation of such clinical applications is considered.

«This is encouraging because the safety profile of anti-muscarinic drugs is well - characterized, with more than 20 years of clinical application for a variety of indications in Europe,» said senior study author Paul Fernyhough, PhD, professor in the departments of pharmacology and therapeutics and physiology at the University of Manitoba in Canada.

Some DIMET students» projects take a disease - driven approach, whereas others start with a basic finding and aim to develop clinical applications.

The foundation envisions the retreat as an opportunity for the postdocs to share research perspectives and for RCT to share views on the interaction of basic biomedical research with the development of clinical applications.

«This result has strong application potential» says Dr. Parise, who has just accepted a new position as research scientist at Oculus VR (Facebook): «A deep understanding of multisensory processing opens new clinical perspectives for neurological syndromes that are associated with multisensory impairments, such as Autism Spectrum Disorder and Dyslexia.

The paper has split scientists, with consensus on the need for a moratorium on clinical applications but disagreement about whether to support basic research on editing genes in human sperm, eggs, or embryos.

Commissioned by ASTRO's Board of Directors as part of the Target Safely campaign, the white paper evaluates the current safety and practice guidance for HDR brachytherapy, makes recommendations for guidance applications to the delivery of HDR brachytherapy, suggests topics where additional guidance is needed and examines the adequacy of general physics, quality assurance (QA) and clinical guidance currently available for the most common treatment sites with regard to patient safety.

Through its effort to develop, produce and distribute a suite of genome RMs, the consortium is providing medical and research laboratories worldwide with the tools they need to advance clinical applications of whole genome sequencing, and the FDA with the ability to conduct science - based regulatory oversight of the technology.

«The current report highlights that a smartphone application can outperform the current standard of care and provide incremental diagnostic yield in clinical practice,» writes Dr. Hibbert, with colleagues.

Raman says the next big steps are in overcoming the technical challenges of delivering the drug, and completing the experiments essential to file for an Investigational New Drug Application with the Food and Drug Administration to start clinical trials.

Many of the early problems that hindered the clinical applications of particulate DDS have been overcome, with several DDS formulations of anticancer and antifungal drugs now approved for clinical use.

Injecting the TRAIL - expressing stem cells into the carotid artery, a likely strategy for clinical application, led to significantly slower tumor growth and increased survival, compared with animals receiving unaltered stem cells or control injections.

Exciting clinical applications of gene editing include correcting the mutation in the bone marrow stem cells of patients with sickle cell disease or hemophilia.

At Houston Methodist, fostering innovations with the potential for clinical application is at the very heart of what we do.

«We're forming collaborations with researchers at Loyola and other centers doing basic science research as well as studies with more immediate clinical applications,» said Michael Zilliox, PhD, director of the Loyola Genomics Facility.

In conjunction with IMNE, the Endocrine Society presents the Diabetes Masters Series, a highly sought, interactive regional meeting series that is in its seventh year of providing healthcare professionals with current evidence on the clinical applications of available and emerging treatment options for patients with type 2 diabetes mellitus (T2DM).

[Clinical applications are close, but will not be dealt with in the same place!]

Although this classification was removed a decade later, since 1965, in order to conduct clinical studies of Coley's Toxins, investigators are required to submit an Investigational New Drug (IND) application with the FDA.

The Center provides them with resources for both blue - sky and de-risking work: blue - sky research follows up on promising but uncertain scientific leads; while de-risking research is necessary to move a promising biomedical discovery through all the rigorous tests required for clinical applications.

In addition, Celvive has partnered with a US - based FDA - approved manufacturer to produce the StemCure ™ cell isolation and delivery system which has been tested to prepare for an IND application with the FDA for the second phase of clinical studies in the US.

harnessing the differentiation potential of pluripotent stem cells to derive interspecies chimera with potential clinical applications.

«Excellent resources for academic education as well as clinical development with respect to genetic testing and application.»

The mission of the Pharmaceutical Chemistry Facility is to provide MDA Faculty with tool compounds for in vitro -, in - vivo - and potentially clinical stuides to advance programs and provide data for grant applications.

The $ 1 million grant will be used for preclinical trial work with the goal of submitting an Investigational New Drug application to the FDA to begin clinical trials.