Sentences with phrase «with clinical infections»

Not exact matches

The drug, with the unwieldy name ceftolozane / tazobactam, has completed Phase 3 clinical trials and could prove particularly effective in dealing with pseudomonas — bacteria usually acquired in hospitals that cause serious interabdominal and urinary tract infections, ultimately resulting in death in some cases.

«The next steps in DPX - RSV will be expensive steps (large RSV infection avoidance studies, or perhaps even challenge studies, will need to be conducted in Phase 3), and so we agree with management's strategy to identify cash - contributing partners before investing its own capital in new DPX - RSV clinical initiatives,» he added.

Remote, retroactive intercessory prayer said for a group is associated with a shorter stay in hospital and shorter duration of fever in patients with a bloodstream infection and should be considered for use in clinical practice.

Diagnosing meningismus normally takes place in a clinical environment, with medical professionals paying attention to the entire medical history in order to determine whether or not a bacterial infection was ever in place.

MRSA Action UK does not however support or agree with Professor Mark Baker's comment in today's media that NICE is considering bringing antibiotics into the existing bonus scheme for GP's not to prescribe these drugs, this is both wrong and immoral as some patients will always require treatment for infections, it is the clinical need that needs to be ascertained and the correct diagnosis determined and appropriate treatment given that needs to be correct.

publish the mandatory collection of data on surgical site infections in this financial year, and introduce a target to reduce these, with year on year reductions in each clinical setting

«A patient diagnosed with an HPV16 infection and lesion needs to undergo careful diagnostic evaluation based on established clinical parameters.

In one analysis that included 21 randomized clinical trials, investigators found a risk of 138 surgical site infections per 1000 procedures, and the use of sutures coated with the antimicrobial triclosan reduced this by 39.

The researchers suggest a clinical trial should be carried out to compare which of the two strategies is better in treating infection, but it will require several thousands of patients with hip infections.

Researchers only discovered this process in the late 1990s, but they've already begun dozens of clinical trials to gauge whether infusing patients with these small RNAs works against a range of diseases, from lung infections to liver cancer to age - related macular degeneration, a sight - stealing condition that mainly affects people over the age of 50.

«The complexity of Lyme disease, combined with lack of biomarkers to measure infection, has slowed progress,» study collaborator John Aucott, head of the Johns Hopkins Lyme Disease Clinical Research Center..

Also recruited were 26 healthy controls, also split nearly evenly between the sexes and about the same ages as the other group, with no clinical history of Lyme disease symptoms and no antibodies to Borrelia burgdorferi that would indicate past or current infection.

Results from three Phase III clinical trials (ION - 1, ION - 2 and ION - 3) evaluating the investigational once - daily fixed - dose combination of the nucleotide analogue polymerase inhibitor sofosbuvir (SOF) 400 mg and the NS5A inhibitor ledipasvir (LDV) 90 mg, with and without ribavirin (RBV), for the treatment of genotype 1 chronic hepatitis C virus (HCV) infection have been presented at the International Liver CongressTM 2014.

«Diagnostic testing combined with clinical expertise is helpful in identifying a cluster of infections that may signal an outbreak,» said Andi L. Shane, MD, MPH, MSc, lead author of the guidelines and associate professor of pediatric infectious diseases, Emory University School of Medicine and Children's Healthcare of Atlanta.

In three new studies in the current issue of the International Journal of Infectious Disease, researchers reported on clinical outcomes in the Kingdom of Saudi Arabia (KSA), how long patients will shed virus during their infections, and how the Sultanate of Oman is dealing with cases that have appeared there.

Molecular, cellular and clinical changes that arise from an infection with a latent virus can result in a decrease in longevity.

While genome sequencing has previously been applied in well - resourced clinical settings to track the spread of MRSA, transmission dynamics in settings with more limited infection control is unknown.

«By demonstrating their effectiveness with live Streptococcal infections, we provide compelling evidence for the potential functionality of the nanosponges in a clinical setting.»

Polansky and Javaherian (both from The Center for the Biology of Chronic Diseasein Valley Cottage, NY) explain the molecular, cellular and clinical changes that result from a latent infection with the CMV and the consequent decrease in longevity.

Hospital - acquired pneumonia (HAP) and ventilator - associated pneumonia (VAP)-- which account for 20 to 25 percent of hospital - acquired infections — should be treated with shorter courses of antibiotics than they typically are, according to new guidelines released by the Infectious Diseases Society of America (IDSA) and American Thoracic Society (ATS) and published in the journal Clinical Infectious Diseases.

Conducted by Prof Rose McGready and Assoc. Prof Daniel Henry Paris from the Shoklo Malaria Research Unit (SMRU) in Mae Sot, Thailand, and the Mahidol Oxford Research Unit (MORU) in Bangkok, affiliated to Oxford University, UK, in collaboration with Prof John Antony Jude Prakash of the Dept. of Clinical Microbiology, Christian Medical College, Vellore, India, the study, «Pregnancy outcome in relation to treatment of Murine typhus and Scrub typhus infection: a fever cohort and a case series analysis,» will be published in the November 20th, 2014 issue of PLOS Neglected Tropical Diseases.

But clinical trials of such a drug, Pfizer's Torcetrapib, were halted in 2006 when investigators discovered that it was associated with an increased risk of death from heart attack and other complications, including cancers and infections.

The researchers said more study is needed to determine if astrovirus infections in nonhuman primates are associated with clinical disease, or whether such infections are asymptomatic.

«We showed that babies are born with flu antigen — specific response, but whether that actually provides clinical protection against infection is still unknown,» Miller says.

The safety and efficacy of these methods have been well established through long - term clinical outcomes studies in the field, with the nasal lining protecting the brain from infection just as the blood brain barrier has done.

In a new paper published this week in the American Journal of Medical Genetics, first author Miguel del Campo, MD, PhD, associate professor in the Department of Pediatrics at University of California San Diego School of Medicine, and colleagues in Brazil and Spain, describe the phenotypic spectrum or set of observable characteristics of congenital Zika (ZIKV) syndrome, based upon clinical evaluations and neuroimaging of 83 Brazilian children with presumed or confirmed ZIKV congenital infections.

In an accompanying editorial, Daniel C. DeSimone, MD, of the Division of Infectious Diseases, and Christopher V. DeSimone, MD, PhD, of the Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, expand on the importance of the study's findings and provide additional insights with more details about S. aureus infections and statin pharmacology, and put these findings into clinical context.

Researchers at St George's, University of London say the new speedy test will mean that for the first time ever patients with common sexual infections will be able to get their diagnosis, results and treatment in one clinical visit.

«Drugs that specifically target PGE2 pathways have already been developed and tested in animals, so our results have excellent potential for clinical translation, not only for the treatment of influenza, but other viral respiratory infections that interact with similar host immune pathways,» says senior study author Divangahi, who is also a member of the Infectious and Immunity Axis at the Research Institute of the McGill University Health Centre (RI - MUHC).

In their new study, they extend these findings by showing that Eritoran — a synthetic inhibitor of TLR4, originally developed by Eisai Inc. for treatment of sepsis — improved clinical symptoms and prevented death when administered up to six days after infection with the influenza virus.

A controlled clinical trial published in January 2013 has shown that fecal transplants can help cure recurrent infections with Clostridium difficile.

Ahead of us now is the major task of exploring the potential of new drug targets, so that hopefully we can prevent the number of people with untreatable infections from escalating further,» says Professor Anders Miki Bojesen, who coordinates the UC - Care research activities at the Department of Veterinary Clinical and Animal Sciences.

«Overall survival for patients with HIV infection after transplant is comparable to that seen in people who were not HIV - infected,» said lead author Joseph Alvarnas, MD, associate clinical professor in the department of hematology and director of value - based analytics at the City of Hope National Medical Center in Duarte, CA.

The clinical presentation, time of illness concurrent with the onset of the outbreak, and presence of neutralizing Abs in convalescent serum all strongly point to primary infection of the researcher by TMAdV.

Second, the clinical presentation of pneumonia and hepatitis is consistent with the known spectrum of disease associated with adenoviral infections.

One of the most vexing problems I face in this clinical role is how to treat children with chronic infections, particularly those suffered by people with cystic fibrosis (CF), chronic endobronchial tubes, and non-CF bronchiectasis.

Understanding the Influence of Genetic Variation and AMR in Enterobacter and Escherichia coli Bloodstream Infections (BSI) by Comparative Genomics and Association with Clinical Outcome Metadata

This research, published today in the online journal PLOS ONE, builds on the 2010 Global iPrEx clinical study, which reported that Truvada, an FDA - approved drug used for years to treat HIV - positive patients, could also prevent new infections in people likely to come in contact with the virus.

Clinical features of bacterial vaginosis in a murine model of vaginal infection with Gardnerella vaginalis.

In collaboration with Dr. Josh Thaden and Vance Fowler, Duke University Medical Center, we are exploring relationships between bacterial genetic variation, emergence of AMR, and patient outcome in Enterobacter and Escherichia coli Bloodstream Infections (BSI) by leveraging the Duke University Bloodstream Infection Biorepository (BSIB), which contains robust clinical data, bacterial bloodstream isolates, and corresponding human sera and DNA from over 2000 patients with BSI caused by Gram - negative bacteria at Duke Hospital since 2002.

Gut Microbiome Composition Predicts Infection Risk during Chemotherapy in Children with Acute Lymphoblastic Leukemia — Hana Hakim — Clinical Infectious Diseases

Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocol.

Curetis N.V. (the «Company» and, together with Curetis USA Inc. and Curetis GmbH, «Curetis»), a developer of next - level molecular diagnostic solutions, today announced the successful completion of clinical performance evaluation and CE - IVD marking of its novel Unyvero Application Cartridge, UTI, for the diagnosis of severe urinary tract infections.

Undiagnosed coinfection with a second RFLP type [19] or with another tickborne infection, such as human granulocytic ehrlichiosis [4], may have contributed to the overlap in clinical symptoms observed among persons infected with the different subtypes (table 2).

The third and fourth SAEs were both ALT elevations that occurred in children with minor clinical symptoms and were determined by serological testing to be caused by a hepatitis B infection.

Therapy escalation in patients with inflammatory bowel disease following clostridium difficile infection is not associated with adverse clinical outcomes: An ibd remedy study [Meeting Abstract]

Infection with different subtypes of B. burgdorferi may help to explain the diversity of clinical presentations of patients with Lyme disease.

The non-specific clinical presentation can be confused with most other arboviruses particularly dengue and chikungunya virus infection.

Fetal neurosonography and magnetic resonance imaging (MRI) have also showed diffuse calcification in the subcortical parenchyma and thalamic areas, ventriculomegaly, lissencephaly, and pachygyria (ie, smooth brains with reduced gyral ridges).6 Nevertheless, to our knowledge, a systematic follow - up of clinical and morphological features of these cases along with anatomic and pathological descriptions associated with congenital ZIKV infection has not been reported.

Human infection with the etiologic agent of Lyme disease, Borrelia burgdorferi, results in disease of a few hallmark clinical signs and multifarious symptoms.