Sentences with phrase «with cobimetinib»

With a median follow - up of 14 months, patients assigned to combination treatment with cobimetinib and vemurafenib had a progression - free survival of 12.3 months compared with 7.2 months for those on vemurafenib alone.

The most common adverse events seen with cobimetinib / vemurafenib were diarrhea, photosensitivity reaction, nausea, pyrexia, and vomiting.

Not exact matches

We discovered our lead compounds, cabozantinib and cobimetinib, and advanced them into clinical development before entering into partnerships with leading biopharmaceutical companies in our efforts to bring these medicines to patients globally.

The US Food and Drug Administration (FDA) has approved the MEK inhibitor cobimetinib (Cotellic) in combination with the BRAF inhibitor vemurafenib for the treatment of advanced metastatic or unresectable BRAF - mutated melanoma.