Sentences with phrase «with complementary sequences»

With relatively straightforward bio-informatics approaches, it was possible to cross-reference expressed miRNAs with complementary sequences of mRNA tags.

Small RNA molecules can bind to and blunt expression of DNA stretches with a complementary sequence.

Instead, a microRNA can bind to a target RNA strand with a complementary sequence, similar to how two strands of «matched» DNA pair up, and prevent that RNA from getting made into a protein.

The Cas9 enzyme is guided to its genomic target sequence by a small guide RNA with a complementary sequence.

In one experiment, they encoded the same sequence on all the octahedron's tethers, and attached strands with a complementary sequence to gold nanoparticles.

As they report in two new studies, the pair and their colleagues constructed viral vectors, each one containing an RNA molecule designed to shut down a gene with a complementary sequence.

Not exact matches

This RNA snippet, known as sgRNA (single guide RNA), contains a sequence of 20 RNA - letters complementary to the genomic target site that scientists have hitherto had to select laboriously by hand or with a variety of online tools.

But with the RNAs that condense into the same droplet, their complementary sequences are really exposed, so they can find each other and base pair to make a higher - order interaction,» Gladfelter says.

A systematic search of the nonrecombining region of the human Y chromosome (NRY) identified 12 novel genes or families, 10 with full - length complementary DNA sequences.

The sequence of the complementary DNA encoding pp40 revealed similarity to the gene encoding MAD - 3, a protein with mammalian I kappa B - like activity.

This was possible because DNA naturally comes with two complementary strands twisted together, and the researchers set up their problem so that every length representing a logical contradiction contained at least one 30 - base sequence and its complement.

By isolating strands of complementary DNA (cDNA) that fit together with mRNA, researchers can figure out what sequence was just translated into mRNA — that is, they can get a read on an expressed gene.

These customized RNAs include complementary sequences that are tailored to match up with specific DNA sequences in the microbe's genome.

With investigations of the conformational properties and interaction stoichiometry of polyribonucleotides of simple and complex sequence (7) and the separation of the complementary strands of DNA and then their renaturation to biologically active duplexes (8), the groundwork was laid for the complementary strand annealing that proved so critical in making gene cloning possible.

The mature miRNA sequence usually starts with A or U, and is often mismatched with the complementary arm, which seems to facilitate arm selection by Argonaute (at least in mammals)(6,9,10).

CEP8 - SA probe complementary to human chromosome 8 - specific centromeric repetitive sequences and directly labeled with SpectrumAqua fluorophore was obtained from Abbott Molecular, Inc. (Des Plaines, IL).

However, being a complex multistep process, cancer cytogenetics are broadened to «cytogenomics,» with complementary resources on: general databases (nucleic acid and protein sequences databases; cartography browsers: GenBank, RefSeq, UCSC, Ensembl, UniProtKB, and Entrez Gene), cancer genomic portals associated with recent international integrated programs, such as TCGA or ICGC, other fusion genes databases, array CGH databases, copy number variation databases, and mutation databases.

Specifically, we have generated clusters of transcripts that behave the same way under the entire spectrum of the sixty - seven experimental conditions; we have assembled genes in groups according to their time of expression during successive days of ES cell differentiation; we have included expression profiles of specific gene classes such as transcription regulatory factors and Expressed Sequence Tags; transcripts have been arranged in «Expression Waves» and juxtaposed to genes with opposite or complementary expression patterns; we have designed search engines to display the expression profile of any transcript during ES cell differentiation; gene expression data have been organized in animated graphs of KEGG signaling and metabolic pathways; and finally, we have incorporated advanced functional annotations for individual genes or gene clusters of interest and links to microarray and genomic resources.

«In Tune With The World» Artists include: Some 29 French and international artists presented in two complementary sequences, with works by: Giovanni Anselmo (1934, Italy), Matthew Barney (1967, USA), Christian Boltanski (1944, France), Mark Bradford (1961, USA), James Lee Byars (1932 - 1997, USA), Maurizio Cattelan (1960, Italy), Ian Cheng (1984, USA), Trisha Donnelly (1974, USA), Dan Flavin (1933 - 1996, USA), Cyprien Gaillard (1980, France), Alberto Giacometti (1901 - 1966, Switzerland), Dominique Gonzalez - Foerster (1965, France), Jacqueline Humphries (1960, USA), Pierre Huyghe (1962, France), Yves Klein (1928 - 1962, France), Henri Matisse (1869 - 1954, France), François Morellet (1926 - 2016, France), Takashi Murakami (1962, Japan), Philippe Parreno (1964, France), Sigmar Polke (1941 - 2010, Germany), Gerhard Richter (1932, Germany), Wilhelm Sasnal (1972, Poland), Kiki Smith (1954, USA), Adrián Villar Rojas (1980, Argentina), Anicka Yi (1971, South KorWith The World» Artists include: Some 29 French and international artists presented in two complementary sequences, with works by: Giovanni Anselmo (1934, Italy), Matthew Barney (1967, USA), Christian Boltanski (1944, France), Mark Bradford (1961, USA), James Lee Byars (1932 - 1997, USA), Maurizio Cattelan (1960, Italy), Ian Cheng (1984, USA), Trisha Donnelly (1974, USA), Dan Flavin (1933 - 1996, USA), Cyprien Gaillard (1980, France), Alberto Giacometti (1901 - 1966, Switzerland), Dominique Gonzalez - Foerster (1965, France), Jacqueline Humphries (1960, USA), Pierre Huyghe (1962, France), Yves Klein (1928 - 1962, France), Henri Matisse (1869 - 1954, France), François Morellet (1926 - 2016, France), Takashi Murakami (1962, Japan), Philippe Parreno (1964, France), Sigmar Polke (1941 - 2010, Germany), Gerhard Richter (1932, Germany), Wilhelm Sasnal (1972, Poland), Kiki Smith (1954, USA), Adrián Villar Rojas (1980, Argentina), Anicka Yi (1971, South Korwith works by: Giovanni Anselmo (1934, Italy), Matthew Barney (1967, USA), Christian Boltanski (1944, France), Mark Bradford (1961, USA), James Lee Byars (1932 - 1997, USA), Maurizio Cattelan (1960, Italy), Ian Cheng (1984, USA), Trisha Donnelly (1974, USA), Dan Flavin (1933 - 1996, USA), Cyprien Gaillard (1980, France), Alberto Giacometti (1901 - 1966, Switzerland), Dominique Gonzalez - Foerster (1965, France), Jacqueline Humphries (1960, USA), Pierre Huyghe (1962, France), Yves Klein (1928 - 1962, France), Henri Matisse (1869 - 1954, France), François Morellet (1926 - 2016, France), Takashi Murakami (1962, Japan), Philippe Parreno (1964, France), Sigmar Polke (1941 - 2010, Germany), Gerhard Richter (1932, Germany), Wilhelm Sasnal (1972, Poland), Kiki Smith (1954, USA), Adrián Villar Rojas (1980, Argentina), Anicka Yi (1971, South Korea).