They're automatic
with cycling times and adjustable suction.
Unprecedented scale, with the capacity to produce up to 1,000 unique mRNA constructs per month, for research, drug discovery and preclinical testing —
with a cycle time of a handful of weeks;
The longer they go on, and the more sophisticated you become
with your cycle timing the more the anxiety grows that something might be wrong.
And, the overall trend across all the recorded data is the same as its been since the end of the LIA, plus or minus an additional quasi-periodic variability
with a cycle time of about 60 years, which also has been in existence since the end of the LIA.
Not exact matches
Trump has had a contentious relationship
with the
Times throughout this election
cycle.
Getting out of the
cycle of flying more leading to less
time with family leading to flying more leading to less
time with family is like breaking an addiction.
Does that mean it's
time to brace for «the singularity» — the hypothesized moment when superintelligent machines start improving themselves without human involvement, triggering a runaway
cycle that leaves lowly humans ever further in the dust,
with terrifying consequences?
With time, I've become more aware of how these
cycles work.
Though his personal political views don't necessarily align
with today's Democratic party, as the New York
Times notes, he has been quite outspoken against Republican nominee Donald Trump throughout this election
cycle.
Break the negative
cycle by scheduling quality
time with the friends and family who energize you.
So it's kind of a lower your expectations mindset, but it's still a market that I want to be involved
with because, but it's just, it's not a
time to bet big, you know, late
cycle is a notoriously difficult part of the
cycle to pin down, whereas midcycle is really the sweet spot.
We often work
with entrepreneurs who are
cycling through the product - development process at the same
time they're raising money.
A team of researchers at UCI had been experimenting
with nanowires for potential use in batteries, but found that over
time the thin, fragile wires would break down and crack after too many charging
cycles.
Though
time is stretched thin during innovation
cycles, jump on opportunities to connect
with friends and family.
Since the company operated
with full -
time employees, not independent contractors, two extra pay
cycles were significant, or in Donovan's words: «the numbers were just completely fucked.»
But working
with new mixtures, pushing them into new materials, and seeing how safe they are over thousands of charge
cycles takes a very, very long
time.
Armed
with the facts about long sales -
cycle times, he has modified his plan to focus on building a larger sales team and putting more prospects in the pipeline.
«In a campaign
cycle that has been nothing but a race to the bottom — at such a critical moment for our nation — and
with so many who have tried to be respectful of a record primary vote, the
time has come for Governor Pence to lead the ticket,» Huntsman told the Salt Lake Tribune.
But
with monthlong high - tech - product life
cycles, just - in -
time manufacturing operations, and overnight global currency crashes, the business world might just be coming around to the marines» point of view.
I align my daily to - do list
with my calendar, literally blocking off
time to complete specific tasks (including training /
cycling).
Thinking back to her
time with Apple, Thompson says it's easy to see why Lululemon has been so successful, because both companies «think about the experience they want to create through the whole life
cycle of the product.
If you're not getting high - quality rest,
with several REM
cycles, your motivation and energy will lag when it's
time to get up in the morning.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations
with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant
cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination
with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from
time to
time in Gilead's reports filed
with the U.S. Securities and Exchange Commission (the SEC).
Factors that could cause or contribute to actual results differing from our forward - looking statements include risks relating to: failure of DBRS to rate the Notes at the anticipated ratings levels, which is a closing condition, or at all; changes in the financial markets, including changes in credit markets, interest rates, securitization markets generally and our proposed securitization in particular; the willingness of investors to buy the Notes; adverse developments regarding OnDeck, its business or the online or broader marketplace lending industry generally, any of which could impact what credit ratings, if any, are issued
with respect to the Notes; the extended settlement
cycle for the scheduled closing on April 17, 2018, which may exacerbate the foregoing risks; and other risks, including those described in our Annual Report on Form 10 - K for the year ended December 31, 2017 and in other documents that we file
with the Securities and Exchange Commission from
time to
time which are or will be available on the Commission's website at www.sec.gov.
With this issue on the minds of marketers, there has been no material move by agencies to find ways to drive down production costs and improve
cycle time.
Moderate interest rates were associated
with a whole range of subsequent returns over the following decade, and we know that those outcomes were 90 % correlated
with the level of valuations at the beginning of those periods (on reliable measures such as market cap / GDP, price / revenue, Tobin's Q, the margin - adjusted Shiller P / E, and others we've presented over
time - see Ockham's Razor and the Market
Cycle).
Often, business owners can optimize cash flow by negotiating longer payment
cycles with creditors and encouraging debtors to pay in shorter
time periods.
Tell us how you worked
with your product teams to validate new product opportunities, reduce risk, accelerate
time - to - market and support every phase of the innovation
cycle.
It's a
time - consuming process that sometimes takes months or years, depending on your sales
cycle, so salespeople should make sure that they're only spending
time with prospects whose pain points align
with your product's solution.
In his free
time he enjoys attending the theatre,
cycling, mountain biking, hiking, reading, studying German, traveling, and spending
time with friends and family.
over at Jay Baer's blog The
time is ripe to ask
with new data available as part of Hubspot's IPO, which confirms they are burning a lot of cash (like everyone else from startup to Amazon) If the Gartner Hype
Cycle holds, Inbound and Social Media are overdue for a beating from the press Don't believe the hype, effective inbound campaigns trump everything Inbound is the right message for the mass market, and will continue to be even if the press beats on it.
For in - house recruiters, the ability to share applicant information
with the relevant hiring manager, as well as schedule interviews and gather feedback from those same hiring managers within one system can save
time and decrease the number of days in the hiring
cycle.
This identical wash, rinse, repeat
cycle has occurred literally hundreds of
times over the past 38 years,
with no serious investigations or prosecutions whatsoever in that this is official, state - sponsored, for - profit corruption.
Is a cost - effective solution for short - term projects and business
cycle peaks Boosts corporate presence on campus Develops a long - term sustainable recruitment strategy, as you can fill full -
time roles
with past Co-op students Students are pre-screened and go through a competitive application process Contributes to the development of the future work force Supports continuous learning
In December, the Federal Reserve increased interest rates for the fifth
time in this
cycle, and
with a stable of more hawkish Fed governors rotating into voting positions, another three or even four rate hikes look likely in 2018.
Because of that, the Eliot Waves Theory seems to traders simple as well as very complicated at the same
time because the sub-divisions and
cycles that this theory deals
with are a bit harder to understand.
The 35 year
cycle chart which touched all -
time lows in 2016 has now turned up
with a vengeance.
Meanwhile, I've been my own harshest critic — particularly
with regard to the unfortunate
timing of my stress - testing decision in 2009 — and have been very open about the challenges that QE and yield - seeking speculation have posed for the methods that resulted: deferring market losses that resulted much more quickly following extremely overextended market conditions in prior historical
cycles.
At one
time, business
cycles were thought to be extremely regular,
with predictable durations, but today they are widely believed to be irregular, varying in frequency, magnitude and duration.
People of color in inner - cities and everywhere have been dealing
with this for a despicably long
time, and the media
cycles just don't cover the
By LEWIS JOHNSON — Co-Chief Investment Officer November 18, 2015 The economy is composed of many different
cycles, each operating
with varying degrees of influence at any given point in
time.
Most of the
time, a given set of market conditions is associated
with some mix of positive and negative outcomes, so we focus on the average of those outcomes in the expectation that doing so will produce good results over the complete market
cycle even if we are incorrect in specific instances.
While most active managers will state that their objective is to outperform over a full market
cycle, they need to be more emphatic
with asset owners up front about how much
time that really entails and why they need it, especially if they state they have a long - term philosophy.
Most of us don't have the skill to
time the market and so you shouldn't be obsessed
with trying to buy at the right
time in the economic
cycle.
Getting out of this trap starts
with the clarity I've outlined — clarity around full market
cycles, around investor
time tolerance and around the need to evaluate performance over longer
time periods.
Minimize claim
cycle times and reduce loss adjustment expenses
with a reliable baseline record for each property.
However, trending information clearly points to the fact that sales reps are having a hard
time making contact
with buyers and don't get involved until much later in the buying
cycle.
And the largest bicycle manufacturer in the world by sales is Giant from Taiwan
with 1.8 bn sales or 7,5
times the sales of Hero
cycles.
Fox News set a record earlier in the month
with 24 million people tuning in to the first Republican primary debate of the 2016 election
cycle, making it the most - watched cable telecast of all
time, excluding sports programming.
Attitudes towards risk can vary
with emotions and stock - market
cycles so why measure risk at one point in
time?