We must be very careful when dealing
with cytotoxic agents, but they can be very useful when handled and delivered appropriately.
Not exact matches
The compound (right panel) has a scorpion - like shape
with two arms grabbing EphA2 - expressing cancer cells, and a tail (brown) constituted by a
cytotoxic chemotherapeutic
agent (paclitaxel used in this work).
Immunologic checkpoint blockade
with anti —
cytotoxic T - lymphocyte — associated antigen 4 (CTLA - 4) or anti — programmed death 1 (PD - 1) / programmed death ligand 1 (PD - L1)
agents seems to have some degree of clinical efficacy in advanced mucosal melanoma, although data are limited to smaller retrospective series or subset analyses of prospective trials.