Sentences with phrase «with decreased survival»

Dysbiosis, or a preponderance of bad gut flora, can «lower circulating lymphocytes, and increase neutrophil to lymphocyte ratio, a finding which has been associated with a decreased survival in women with breast cancer,» researchers argue in a study published in ISRN Oncology.

«Active surveillance of intermediate - risk prostate cancer associated with decreased survival.»

Not exact matches

Quick execution of each and every link is critical because the chances of survival decrease 7 to 10 % with each passing minute.

Survival curves showed that partial breast - feeding and exclusive breast - feeding were linked with a decreased risk for SIDS at all ages.

In many patients diagnosed with LUAD, tumors cells have already spread to the brain, leading to decreased quality of life and low survival rates.

Median progression - free survival for the 13 patients who had a decrease in the number of CTCs with ALK copy number gain was 14.0 months, while the median progression - free survival for the 16 patients who had stable or increased numbers of CTCs with ALK copy number gain was 6.1 months.

Among patients with non-small cell lung cancer (NSCLC) fueled by ALK gene alterations who were being treated with crizotinib (Xalkori), a decrease in the number of circulating tumor cells (CTCs) harboring increased copies of the ALK gene over the first two months of treatment was associated with increased progression - free survival.

«These findings will give women with early stage breast cancer greater certainty that anti-estrogen therapy will decrease their risk of recurrence and increase their chance for survival whereas chemotherapy will not,» said breast cancer survivor Mary Lou Smith, JD, MBA, who helped design the study as a leader in the ECOG - ACRIN Cancer Research Advocates Committee.

«This finding suggests a novel therapeutic target to decrease invasion of tumor cells in patients and may also provide a novel biomarker that could help predict survival of patients with glioblastoma,» explained Israel.

Tumor size in mice injected with the antibody steadily decreased over time, while their survival increased.

In fact, a victim's chance of survival decreases by 10 percent with each passing minute.

The presence of barred owls was associated with decreasing spotted owl survival rates in some study areas and spotted owls were disappearing from many of their historical breeding territories as those areas were invaded by barred owls.»

While advantages in PFS and OS emerged in an overall meta - analysis of the entire group, the survival benefit associated with obesity was restricted to men treated with targeted or immunotherapies, where obese men had a 47 percent decreased risk of death compared to men with normal BMI.

Under this scenario, few women would experience menopause (decreased fertility with continued survival) because few would survive much longer than they reproduced.

«Our results show that, in an era in which high - resolution molecular typing for class I and class II HLA [human leukocyte antigen] loci has significantly improved the clinical outcome of unrelated donor HSCT by decreasing the risk of immunological complications, lowering the ATLG dose to 15 mg / kg did not affect the time to engraftment and, more importantly, the incidence of acute or chronic GVHD [graft - vs - host disease], and was associated with an improved probability of event - free survival, mainly due to a reduced risk of nonrelapse mortality,» wrote Franco Locatelli, MD, of the department of oncoematologia pediatrica, IRCCS Ospedale «Bambino Gesù» in Rome, and colleagues.

Using a TCGA data set with 971 invasive breast cancer patients, we found that patients with alterations in the expression of ABL2 and eight validated downstream targets (TAZ, AXL, CTGF, STAT5A, STAT5B, TNC, IL6, and MMP1) exhibited decreased disease - free survival (Fig. 8A).

Furthermore the bCSC - DMR signature was associated with a decrease in relapse ‐ free survival (RFS)(See Figure).

Clinical studies identify FLT3 ITD mutations associated with higher numbers of leukemic cells, increased incidence of relapse and decreased overall survival.

The decrease in clone numbers in IRP individuals was associated with shorter survival time.

Her long - term goal is to combine conventional and immune therapies in ovarian cancer in order to permit disease control by the immune system, with decreased toxicity and increased survival.

Many clinical studies have found that FLT3 ITD mutations are associated with higher concentrations of leukemic cells in both blood and bone marrow, increased incidence of relapse and decreased overall survival.

Tumor hypoxia is often linked to decreased survival in patients with breast cancer and has been shown to induce specific molecular changes in cells including changes that confer a more malignant phenotype such as increased proliferation (3), survival (4), invasion (5), and metastasis (6).

In absence of WDR47, the exhaustion of late cortical progenitors and the consequent decrease of neurogenesis together with the impaired survival of late - born neurons are likely yielding to the worsening of the microcephaly phenotype postnatally.

Treatment with a single RTK inhibitor had little effect in these tumors, but combined therapy to target several RTKs (with Iressa / Tarceva / Gleevec, etc.) decreased signaling, cell survival, and anchorage - independent growth in GBM.

This is consistent with reports associating regular exercise with reduced incidence of dementia3 and several cancer types.26 - 28 Potential reasons for improved functional status and survival among regular exercisers may include increased cardiovascular fitness and improved aerobic capacity and organ reserve,29 - 31 increases in skeletal mass and metabolic adaptations of muscle with decreased frailty,29 - 31 lower levels of circulating inflammatory markers, 32 improved response to vaccinations, 33 and improved higher - order cognitive functions.34

What is clear is that for many gay youth, middle school is more survival than learning — one parent of a gay teenager I spent time with Tyler Barney, a high school student in Mt Juliet, said he made the discovery that decreased performance has to do with phones lithium - ion batteries when

Survival rates after a cardiac arrest decrease approximately seven per cent to ten per cent with every minute that defibrillation is delayed.

With PAIRIN, those soft skills defined by Yong Zhao as «the new survival skills,» allow educators to specifically target behavior and mindset development among their students that leads to increased academic performance, fewer dropouts, and decreased behavioral issues.

The addition of Enalapril or Benazapril to conventional therapy in dogs with chronic congestive heart failure resulted in a significant decrease in clinical signs and a 92 % increase in survival time.

Given the critical importance of treatment adherence to the long - term survival of individuals with CF, and given the characteristic decrease in treatment adherence observed across the adolescent period (Quittner et al., 2000; Ricker et al., 1998), the current findings offer promising avenues for future research on both the benefits and risks of peer relationships for youth with CF. Furthermore, health - related quality of life increasingly has been recognized as a critical element of patient and family - reported outcomes among youth with chronic illness (Quittner et al., 2008), and the current findings continue to build on this growing body of literature for youth with CF.

These advances have improved survival for infants with increasingly lower gestational ages, and have decreased morbidity for low and very low birth weight infants [38], [39].