Sentences with phrase «with developing the phase»

At BI I wear many hats and perform many functions, the most interesting of which is that I am part of an international team charged with developing the phase I to phase III clinical research program for a new chemical entity.

Not exact matches

Juno is developing its immunotherapy product candidate, JCAR017, which is in a Phase I trial, studying patients with B - cell Non-Hodgkin Lymphoma [NHL].

• What is human - centered marketing and why it is important now • The three critical phases of a human - centered approach • How to research and develop human understanding of customers • How to use personas with human - centered marketing • How to understand human - centered experience scenarios and plan for them • How to humanize content and messaging to connect with customers

The validation achieved in phase 2 will provide you with information that can be used to develop your positioning statement.

The Build Accelerator is a startup accelerator program focused on early revenue startups, those who have progressed beyond the idea phase with initial market traction, and are developing the entrepreneurial skills required to grow the company with a strong emphasis on sales and marketing at scale.

Using a Lean Startup Methodology tailored for communities of color, DID excels at 1) finding Black and Latina women entrepreneurs with high growth companies and game changing ideas, 2) connecting them to an unmatched network of investors, mentors, and influencers, 3) developing their start - up toolkit and leadership skills, and 4) supporting their entrepreneurship journey from the build phase to exit with the goal of helping create companies that have a strong positive impact on the economic health of their local communities.

Maastricht, The Netherlands, 1 November 2017 — Cristal Therapeutics, a clinical stage biopharmaceutical company developing targeted nanomedicines for the treatment of cancer and other diseases with high unmet patient need, announced today that it has begun a Phase 1b...

And through my travels, I discovered that Christianity in China is entering a new phase: Where it once carried thick association with Western cultural influence, it has now developed into something truly Chinese.

In this paper I shall develop a view of perception from the partial theory to be found in Whitehead's early philosophical writings and defend it against objections which led Whitehead himself to replace it later with a somewhat different theory.1 Development of the Early Theory The first phase or moment of perception is sense - awareness (CN...

Ford began to develop this line of thought in the early 1980s, coincident with the completion of the first major phase of his textual study of Whitehead, and has emphasized this direction increasingly since that time.4

Their major physical and mental developmental phase happens during this time and this baby walker with wheels help develop this skill

(read more) I hope you'll find all of my effort and experience uniquely qualifies me to assist you in developing your special birth plan, executing it and preparing you for the beginning phases of motherhood as I have with so many previous families.

During this initial learning phase, providing your baby with a walker will help them develop strong muscles and master their walking skills without having their resolve shaken by too many falls, bumps, and bruises.

Rosengarten already has received town approval to develop just over 40 acres of the Mastic property in a phased development that would leave another 20 acres for future development, along with a structure.

CritiTech will be working with the U.S. Food and Drug Administration when it comes to the next phases of testing and developing Nanotax.

After spending a month in Germany learning about making candy, Ràfols was charged with developing new flavors, formulations, and shapes for the sweets, overseeing all phases of their development from concept to market.

White and colleagues will work with other collaborators at the Cancer Institute to develop early - phase patient clinical trials based on the findings from this study in the near future.

The last phase involves a mix of individual, group, and family therapy, developing non-erotic support systems with men, and introducing the patient to a married couple that «function [s] as special companions.»

Scenario 1: Near - normal season if La Niña develops and the conditions associated with a low - activity phase and cool AMO also develop.

Scenario 2: Above - normal season if both La Niña and the conditions associated with the high - activity phase and warm AMO develop.

Scenario 3: Below - normal season if La Niña does not develop and conditions typically associated with a low - activity phase and cool AMO do develop.

The animals treated with ribavirin appeared normal during the treatment phase but developed severe disease shortly after treatment ended.

The study is investigator led and has therefore focused on clinical need, targeting patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a novel mechanism of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point from which to develop trials of progressive disease.»

Results from a phase III trial with another antibody that targets β amyloid — solanezumab, developed by Eli Lilly — should be announced later this year.

Vertex has already developed a drug cocktail for patients with the most common CF mutation — responsible for the overwhelming majority of cases — with phase III clinical trials underway.

Researchers at Massachusetts Eye and Ear / Harvard Medical School and the University of Crete have conducted a phase I / II clinical trial investigating the efficacy of statins (cholesterol - lowering medications) for the treatment of patients with the dry form of age - related macular degeneration (AMD)-- the leading cause of blindness in the developed world.

«Permanent data storage with light: Researchers develop the first non-volatile all - optical chip memory based on phase change materials.»

However, in this Phase II clinical trial, designed to prospectively evaluate the safety and effectiveness of ACHT for patients with HIV - related lymphoma, researchers discovered that this population had no greater likelihood of developing these complications compared to those without the virus.

Pr J.A. Sahel (chief of the «Institut de la Vision» — Inserm, CNRS, Université Paris VI), a member of the French Académie des Sciences, then presented a cell therapy phase I clinical trial project for retinitis pigmentosa developed in collaboration with I - Stem.

In my role as a Clinical Professor of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Professor of Medicine and Director of Early Phase Clinical Trials Program in the Department of Medicine at Roswell Park Comprehensive Cancer Center, I am developing novel therapies for patients with cancer.

Michael Pfreundschuh and colleagues Ugur Sahin and Ozlem Türeci at the University of Saarland develop SEREX (SErological analysis of Recombinant cDNA Expression), providing a powerful method to analyze the humoral immune response to intracellular cancer antigens and ushering in the third phase of cancer serology, bringing with it the prospect of providing a comprehensive view of the immune recognition of human cancer.

A Phase III, Multicenter, Randomized, Placebo - Controlled, Double - Blind Study Of Atezolizumab (Anti − PD - L1 Antibody) As Adjuvant Therapy In Patients With Renal Cell Carcinoma At High Risk Of Developing Metastasis Following Nephrectomy

An anti-PD-1 antibody developed by Bristol - Myers Squibb generates excitement with results from a phase I trial showing that, among 236 patients with various types of cancer, the treatment shrank tumors in 28 percent of melanoma patients, 30 percent of patients with kidney cancer, and 18 percent of patients with advanced non-small cell lung cancer.

CT - 011, developed by Israel - based Curetech Ltd, is also being tested in phase II trials in metastatic melanoma, colorectal cancer in combination with chemotherapy, advanced renal cell and prostate cancers, as well as in acute myeloid leukemia.

She is CEO of PsychoGenics Inc., a profitable preclinical CNS service company, CEO of PGI Drug Discovery LLC, a company engaged in psychiatric drug discovery with three partnered Phase II clinical programs and Adjunct Associate Professor of Neuroscience at Mount Sinai School of Medicine, Dr. Leahy has more than 25 years of experience in drug discovery, clinical develop and business development for pharmaceutical and biotechnology companies, including extensive knowledge of technology assessment, licensing, mergers and acquisitions, and strategic planning.

Researchers in China, along with colleagues in the US, have developed a new catalyst that shows outstanding hydrogen - production activity and stability in the low - temperature aqueous phase reforming of methanol (APRM).

Researchers in the US have developed an optimized solid - phase microextraction method for extracting volatile organic compounds from cells infected with viruses, as a way of diagnosing viral diseases.

Roche (SIX: RO, ROG; OTCQX: RHHBY) and Prothena Corporation plc (NASDAQ: PRTA), announced today that they have entered into a worldwide collaboration to develop and commercialize antibodies that target alpha - synuclein, including PRX002... which is currently in preclinical development and is expected to enter Phase 1 clinical trials in patients with Parkinson's disease in 2014.

There have been a number of challenges with these new drugs, and they haven't really made it to phase three clinical trials, and so the reason is that it's very difficult to develop very specific inhibitors, because there is a large family of these phosphatases and it's difficult to ensure a specificity of your drug.

Our group has 3 major goals: Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple myeloma

Astrobotic, in partnership with Carnegie Mellon University, has been selected by NASA to receive a Phase II SBIR award to develop a small lunar rover capable of carrying on small scale science and exploration on the Moon and other planetary surfaces.

REU participants will conduct original research via specially designed student projects within three main foci: 1) Microgel and Hydrogel Nanoparticles: Designing environmentally sensitive nanoparticles for a variety of applications and fundamental studies of volume phase transitions; 2) Anisotropic Soft Matter Thin Films: Driving self - assembly of soft matter to develop thin films with unique properties tied to the shape anisotropy of the materials; and 3) Soft Matter Fluid Flow: Striving to better understand and to improve mixing in liquid soft matter systems and use liquid flow to test and understand biological phenomena.

Missions to develop these themes are budgeted with a total cost that includes construction, mission operations, and data analysis as one package in the mission's prime phase; the funding level for operations and data analysis during the mission's subsequent extended phase is determined by competitive review among all operating missions (NASA's Senior Review process).

To further develop genetically directed early phase clinical trials — in part through Center for Cancer Targeted Therapeutics (C2T2), Early Cancer Therapeutics Consortium (ECTC), National Clinical Trials Network (NCTN) with Molecular Analysis for Therapy Choice (MATCH).

JCAP's high - throughput team has partnered with computer scientists from Cornell University to develop a new method for rapid construction of phase diagrams using data from JCAP's collaboration with Stanford Synchrotron Radiation Lightsource Laboratory.

If you don't keep a consistent sleep schedule — even with short interruptions, such as going to bed later and eating at different times on the weekend ---- you risk developing a sleep - phase disorder.

The 3 basic phases of strength are: GENERAL STRENGTH: (developed with standard weight training equipment, body weight exercises, etc...)

Conversion to Power In this phase, you build on the strength developed in phase 1 with training that will increase your ability to move a load at high velocity.

It is basically by enhancing who you are, becoming major with every phase, developing an picture of achievements and by knowing in it in every phase of the way.

Certainly, modern formal education and training systems were developed with young people in mind — people seen to be going through an initial learning phase in their lives, to be doing a whole range of things for the first time, and to be doing these things all together at more or less the same ages.