«One of the ways to truly realize the full value of human genetics, is to make our research synergistic
with drug development efforts where target discovery, validation and prioritization efforts can be accelerated,» said Kari Stefansson, M.D., Dr. Med., founder and CEO at deCODE Genetics.
Not exact matches
With a critical mass of 450,000 patients annually among them, the six centers have agreed to combine their
efforts on planning clinical trials in immunotherapy, recruit patients quickly, and share the information learned — which could be the single biggest factor in speeding up
drug development.
But rather than buying up a genetic research outfit, it decided to build its own in the form of the Regeneron Genetics Center (RGC), an ambitious four - year old
effort to sequence as many exomes (the protein - encoding part of the genome) as possible, pair them
with medical records, and accelerate
drug development.
Their discovery of the LDL receptor and their
efforts to understand how the protein functioned are credited
with laying the foundation for the
development of the blockbuster class of cholesterol - lowering statin
drugs.
Drug development efforts based on harmine will need to grapple
with its known psychoactive effects on the brain, which may explain its traditional use in spiritual ceremonies and as medicine.
This
effort will combine academic groundbreaking discoveries
with drug discovery expertise and
development traditionally only found in the pharmaceutical industry.
«Our intellectual property portfolio is advancing in parallel
with our AV411
development efforts for pain states and certain
drug addiction conditions, thus creating a cohesive program.»