BACKGROUND: Allelic variation of the monoamine oxidase A (MAOA) gene has been implicated in conduct disorder and antisocial, aggressive behavior in humans when associated
with early adverse experiences.
Not exact matches
Our findings add insight into the pathways linking
early childhood adversity to poor adult wellbeing.29 Complementing past work that focused on physical health, 9 our findings provide information about links between ACEs and
early childhood outcomes at the intersection of learning, behavior, and health.29 We found that ACEs
experienced in
early childhood were associated
with poor foundational skills, such as language and literacy, that predispose individuals to low educational attainment and adult literacy, both of which are related to poor health.23, 30 — 33 Attention problems, social problems, and aggression were also associated
with ACEs and also have the potential to interfere
with children's educational
experience given known associations between self - regulatory behavior and academic achievement.34, 35 Consistent
with the original ACE study and subsequent research, we found that exposure to more ACEs was associated
with more
adverse outcomes, suggesting a dose — response association.3 — 8 In fact,
experiencing ≥ 3 ACEs was associated
with below - average performance or problems in every outcome examined.
This paper hypothesises that the population of children receiving a clinical diagnosis of ADHD is aetiologically heterogeneous: that within this population, there is a group for whom the development of ADHD is largely genetically driven, and another who have a «phenocopy» of ADHD as a result of very
adverse early childhood
experiences,
with the prevalence of this phenocopy being heavily skewed towards populations living
with poverty and violence.
Relative to children
with no ACEs, children who
experienced ACEs had increased odds of having below - average academic skills including poor literacy skills, as well as attention problems, social problems, and aggression, placing them at significant risk for poor school achievement, which is associated
with poor health.23 Our study adds to the growing literature on
adverse outcomes associated
with ACEs3 — 9,24 — 28 by pointing to ACEs during
early childhood as a risk factor for child academic and behavioral problems that have implications for education and health trajectories, as well as achievement gaps and health disparities.
Because many of the biological alterations associated
with early stress in preclinical studies have been reported in adults
with depression, it has been hypothesized that the neurobiological changes associated
with adverse early experiences may confer a vulnerability for the development of depression (6, 8).
Fortunately, it is posited that our psychological profiles are malleable, so intervening
with positive contextual factors, such as more attentive caregiving, can reduce the impact of
early adverse experiences of children (Kreidler & Kurzawa, 2009; Weitzman & Cook, 1986).
The evaluation of the
early effects (short - run) of SSLP found mixed effects,
with beneficial effects for some groups, but
adverse effects for children from families
with higher needs and
experiencing greater disadvantage.3 Results from the second phase of the evaluation were more positive.
Coupled
with this research is the landmark
Adverse Childhood
Experiences Study (ACE)(Felitti, et al., 1998) which reviewed the health of more than 17,000 mid-life adults and confirmed that early exposure to negative childhood experiences of abuse, neglect and witnessing violence leads to lifelong, debilitating mental and physical health problems, and ultimately, early
Experiences Study (ACE)(Felitti, et al., 1998) which reviewed the health of more than 17,000 mid-life adults and confirmed that
early exposure to negative childhood
experiences of abuse, neglect and witnessing violence leads to lifelong, debilitating mental and physical health problems, and ultimately, early
experiences of abuse, neglect and witnessing violence leads to lifelong, debilitating mental and physical health problems, and ultimately,
early mortality.
Adverse experiences in
early life may leave some predisposed to health - damaging behaviours,
with fame and extreme wealth providing greater opportunities to engage in risk - taking.
The study provides useful information for the identification of potential explanatory mechanisms and we interpret the findings in accordance
with the attachment literature, which has consistently identified
adverse experiences with early caregiving figures as precursors to later attachment difficulties (for reviews, see [13, 14]-RRB-.
She is also a co-investigator on a randomized efficacy trial of a school readiness intervention program
with foster children and a multisite Center investigating the behavioral and neurobiological impacts of
early adverse experiences in humans and nonhuman primates.
Research shows that children who are most likely to be suspended or expelled — children from low - income families, children of color, and children
with certain disabilities — are also most likely to benefit from high - quality
early education.10 Children from low - income families and children of color are more likely to
experience multiple
adverse childhood
experiences (ACES), which can manifest as challenging behaviors that trigger suspensions or expulsions.11 Likewise, young children
with language delays or trouble
with self - regulation may struggle to verbalize appropriate responses to emotional or physical stimulation, and instead display inappropriate behavior.12 In both cases, appropriate evaluation and intervention services can help children learn important coping and communication skills.
Compared
with those reporting no
adverse childhood
experiences, persons reporting 5 or more categories had substantially higher risks of
early smoking initiation (odds ratio [OR], 5.4; 95 % confidence interval [CI], 4.1 - 7.1), ever smoking (OR, 3.1; 95 % CI, 2.6 - 3.8), current smoking (OR, 2.1; 95 % CI, 1.6 - 2.7), and heavy smoking (OR, 2.8; 95 % CI, 1.9 - 4.2).
Because
adverse childhood
experiences are common and strongly associated
with smoking initiation, preventing their occurrence56 and
early identification and treatment of children exposed to them may reduce smoking initiation among adolescents.