Sentences with phrase «with early stages of the disease»

She states, «Up until now, we've focused on cats with early stages of the disease with the hope of slowing disease progression.

Cats with mild or moderate forms (or perhaps those with early stages of the disease) often benefit from increased dietary fiber, administration of laxatives or stool softeners of various kinds, and drugs called prokinetic agents (like cisapride) that stimulate the muscles of the colon.

Not exact matches

Comparing a new patient's information with millions of other cases, Patient Rescue might be able to predict that they are in the early stages of a disease that has not yet become symptomatic, for example.

Patients with early - stage and advanced OA, RA or other inflammatory joint disease were recruited for the study alongside a control group of those with good skeletal health, with plasma and synovial fluid samples from both groups being analysed using mass spectrometry.

Studies on the origins of BSE — a fatal disease marked in the early stages by loss of balance — gained urgency with the 1996 emergence in humans of the BSE - like new variant Creutzfeldt - Jakob disease (nvCJD).

«Patients diagnosed with early - stage prostate cancer — and that's the vast majority of patients with this disease — face many treatment options that are thought to be similarly efficacious,» said Ronald C. Chen, MD, MPH, UNC Lineberger member and associate professor in the UNC School of Medicine Department of Radiation Oncology.

While women with early stage breast cancer often are cured of their disease, they live with surgical consequences throughout survivorship.

«We believe that we have made an important step forward in minimising post-operative complications for patient with early HNSCC, enabling a more accurate identification of the stage of their disease, and reducing the cost to healthcare systems at the same time,» Prof de Bree will conclude.

Adding two blood - borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.

«Awareness of this silent, but deadly killer may help prevent those with early - stage kidney disease from progressing,» Saran says.

Treatment of knee osteoarthritis is shifting focus from end stage treatment to preventing the progression from early to the late stage of the disease, with the specific aim of decreasing the need for joint replacement and other costly treatments.

«Physical therapy not associated with improvements in patients with early stages of Parkinson's disease.»

The same was also seen for the sub-group of patients with early stage I disease.

So now, with late - stage clinical failures piling up, the U.S. Food and Drug Administration (FDA) has set off down a path to adapt those standards as researchers are pushed inexorably into earlier and earlier forms of the disease, ahead of the brain damage inflicted by Alzheimer's.

«Although there is a high risk of progression to decompensated cirrhosis and liver cancer among patients with advanced fibrosis, limiting access to people who have already progressed to late - stage disease as compared to treating earlier to prevent these liver - related complications seems counter-intuitive as a public health strategy.»

Future refinements should sharpen the method's ability to accurately identify Alzheimer's disease at an early stage — prior to the onset of clinical symptoms — in a primary care setting, with just a simple blood extraction.

But the early stage work is promising, he says, because it holds out hope that doctors will soon be able to image breast cancer with several techniques simultaneously, significantly increasing the chances of spotting the disease in its earliest stages.

A more attainable goal may be regenerative tissue transplants, for example, replacing dying liver cells in someone with early - stage liver disease with chunks of healthy stem cells from a personalized liver organoid.

People in the study with more severe stages of the disease did not have lower levels of caffeine in the blood, suggesting that the decrease occurs from the earliest stages of the disease, according to David G. Munoz, MD, of the University of Toronto in Canada, who wrote an editorial accompanying the study.

«With a better understanding of how potential is regulated, it could be possible to broaden the development spectrum of aging stem cells, allowing them to regain their capacity to produce cell types from earlier development stages, which in the long - term perspective could be relevant to future treatment methods for neurodegenerative disease.»

When factoring in what is now known about breast cancer biology and heterogeneity, breast conserving therapy (BCT) may offer a greater survival benefit over mastectomy to women with early stage, hormone - receptor positive disease, according to research from The University of Texas MD Anderson Cancer Center.

High - intensity exercise three times a week is safe for individuals with early - stage Parkinson's disease and decreases worsening of motor symptoms, according to a new phase 2, multi-site trial led by Northwestern Medicine and University of Denver scientists.

This lack of new memories, along with the preservation of older ones, may be what leads to the outdated sense of self — or «petrified self» — often seen in the early stages of the disease.

«With this study, we have gained new knowledge about the disease processes in the brain in the early initial stages of the disease development.

Quercetin did not prevent all of the symptoms associated with the disorder but researchers hope that it could offer a useful treatment option in the early stages of disease.

Early identification of patients with risk factors for a number of disorders would allow for early treatment that could potentially stop the development of disease in its earliest stEarly identification of patients with risk factors for a number of disorders would allow for early treatment that could potentially stop the development of disease in its earliest stearly treatment that could potentially stop the development of disease in its earliest stages.

An initial clinical trial of simvastatin in people with early - stage MS showed reductions in brain lesions, suggesting an effect on the underlying disease process.

According to forensic pathologist Bennet Omalu of the University of Pittsburgh, an autopsy after his death revealed that Waters» brain had suffered so much damage from football injuries that it resembled that of an 85 - year - old man with early stage Alzheimer's disease.

Conducting a cross-sectional study of a large cohort of patients with different levels of cognitive impairment and different disease stages, the researchers found that the amounts of a TREM2 fragment in the cerebrospinal fluid were highest during early stages characterized by mild cognitive impairment symptoms.

In some cases, late onset of the disease can also occur if the infection is not detected at an early stage or if it is not treated with antibiotics.

The drug, bexarotene, was found to reduce levels of the neurotoxic protein amyloid - beta in experimental mice with late - stage Alzheimer's but to increase levels during early stages of disease.

«Every patient with dementia has a unique narrative, which if captured in the earlier stages of the disease, enables clinicians and their families to understand the origin of their distress.

here is epidemiological evidence that links type B coxsackie virus (CVB) infection with heart disease, and research published on July 31st in PLOS Pathogens now suggests a mechanism by which early infection impairs the heart's ability to tolerate stress at later stages of life.

«Pancreatic cancer is a disease with a poor prognosis, mainly because of the inability to detect the tumor at an early stage, its high potential for early dissemination, and its relatively poor sensitivity to chemotherapy or radiation therapy,» according to background information in the article.

The new studies find high activity with investigative drugs for advanced melanoma, and show for the first time that ipilimumab, a treatment already approved for advanced melanoma, can substantially decrease the risk of melanoma recurrence in certain patients with earlier - stage disease.

Dogs diagnosed with bone cancer often arrive at the clinic at a very advanced stage of the disease, whereas in humans, bone cancer is usually detected early because people complain about the pain and have it investigated.

«This study demonstrates that Prosigna can reliably identify early stage breast cancer patients who have a low risk - of disease recurrence at 10 years, including a substantial proportion of patients with node - positive disease for whom the risk / benefit derived for adjuvant chemotherapy would be at best neutral,» said Dr. Alessandra Cesano, chief medical officer of NanoString Technologies.

«They complemented their scientific expertise by working closely with clinicians and advocates from the very early stages of the project, which provided a deeper understanding of how the disease impacts patients and how the treatment can best help them.»

«These results have driven us to update our treatment guidelines in Denmark to include testing with Prosigna as part of the workup of postmenopausal women with early stage HR - positive / Her -2 negative breast cancer, including patients with node - positive disease.»

For more information regarding Bristol - Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: • Early stage IB - IIIA, operable non-small cell lung cancer, confirmed in tissue • Lung function capacity capable of tolerating the proposed lung surgery • Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 - 1 • Available tissue of primary lung tumor Exclusion Criteria: • Presence of locally advanced, inoperable or metastatic disease • Participants with active, known or suspected autoimmune disease • Prior treatment with any drug that targets T cell co-stimulations pathways (such as checkpoint inhibitors) Other protocol defined inclusion / exclusion criteria could apply

Because of the success of early treatment, some research suggests that people with liver diseases should routinely be screened for HE through cognitive tests so that HE can be caught and treated before it progresses into the more advanced stages.

In early stages of HIV infection, HIV predominantly uses the CCR5 co-receptor, whereas during the disease progression HIV uses either CXCR4 alone or in combination with CCR5 in about 50 % of the infected individuals [18, 19].

«Patients diagnosed with early - stage prostate cancer — and that's the vast majority of patients with this disease — face many treatment options that are thought to be similarly efficacious,» said Ronald C. Chen, MD, MPH, associate professor in the UNC School of Medicine Department of Radiation Oncology.

In the study, which was conducted in collaboration with researchers at UC San Francisco and published today in the Journal of Neuroscience, scientists transplanted inhibitory neuron progenitors — early - stage brain cells that have the capacity to develop into mature inhibitory neurons — into two mouse models of Alzheimer's disease, apoE4 or apoE4 with accumulation of amyloid beta, another major contributor to Alzheimer's.

But there's another group of PD symptoms, termed the «non-motor symptoms» (NMS) of PD, that gets far less attention, even though NMS begin to manifest earlier in the disease, are harder to treat with current therapies, and include some of the most crippling features of living with the later stages of PD.

Both recent experience with immunotherapy for clearance of Aβ in AD, and their own (and Prothena's) experience with AS - clearing immunotherapies in animal models, indicate that in order to be effective as disease - modifying agents when administered alone, therapies that remove proteinaceous aggregates from the brain must be initiated in the early clinical or even preclinical stages of the disease, before the burden of other forms of aging damage becomes entrenched.

In summary, we demonstrate similar neurological / motor function deficits in SOD1 and PFN1 mice, both exhibiting clinically - relevant attributes of Amyotrophic lateral sclerosis (ALS), with more advanced computer vision systems identifying distinctive behavioral patterns and discriminating the phenotype at very early disease stages in both models.

We will be able to establish how protein levels in the blood taken at the very early stages of MS correlate with how the disease behaves ten years down the road, juxtaposing the biomarker with clinical, genetic, and imaging data already available.»

The latter result indicates that homocysteine - lowering may have to be targeted at those with early stages of Alzheimer's disease.

identify disease in its earliest stages and determine the exact location of a tumor, often before symptoms occur or abnormalities can be detected with other diagnostic tests