Sentences with phrase «with efficacy of»

With the efficacy of moderately intensive parent training well established, it now seems appropriate to determine if the moderately - intensive treatments are superior to briefer, less costly interventions, particularly because families frequently attend relatively few sessions, often five to eight or fewer (Armbruster & Kazdin, 1994; Kazdin & Wassel, 1998), well below the number recommended by these programs.

Gastric Mucosal Atrophy Might Be Associated with the Efficacy of First - Line Therapy Using Vonoprazan for Helicobacter pylori

Our patent - pending algorithm helps score the accuracy of the candidate's answers along with the efficacy of the explanation.

My other frustration was with the efficacy of Amazon's search, whether using Alexa or not.

This combines the simplicity and fairness of a revenue - neutral carbon tax with the efficacy of an economy - wide cap.

I was very impressed with the efficacy of Zylkene in treating my cat's anxiety - related issues.

Regular bathing will not interfere with the efficacy of the product, but if the pet needs frequent bathing, reapplication more often than once a month may be necessary (but no more than once a week).

DRUG INTERACTIONS Carbohydrases may increase intestinal glucose absorption and may thus interfere with the efficacy of oral hypoglycemic drugs or insulin.

For eventual human application, lowest doses of a drug are always desirable but this must be balanced with efficacy of the compound.

This «hybrid» system combines the excellent visible light absorption properties and the great stability of inorganic semiconductors with the efficacy of molecular catalysts.

It can also affect physical function and interfere with the efficacy of therapies,» Herbst said.

«Our findings point to the importance of physicians counseling their patients regarding the potential harms of smoking interfering with the efficacy of therapies and for increased risks of side effects.»

Not exact matches

Topics included: early reporting on inaccuracies in the articles of The New York Times's Judith Miller that built support for the invasion of Iraq; the media campaign to destroy UN chief Kofi Annan and undermine confidence in multilateral solutions; revelations by George Bush's biographer that as far back as 1999 then - presidential candidate Bush already spoke of wanting to invade Iraq; the real reason Bush was grounded during his National Guard days — as recounted by the widow of the pilot who replaced him; an article published throughout the world that highlighted the West's lack of resolve to seriously pursue the genocidal fugitive Bosnian Serb leader Radovan Karadzic, responsible for the largest number of European civilian deaths since World War II; several investigations of allegations by former members concerning the practices of Scientology; corruption in the leadership of the nation's largest police union; a well - connected humanitarian relief organization operating as a cover for unauthorized US covert intervention abroad; detailed evidence that a powerful congressional critic of Bill Clinton and Al Gore for financial irregularities and personal improprieties had his own track record of far more serious transgressions; a look at the practices and values of top Democratic operative and the clients they represent when out of power in Washington; the murky international interests that fueled both George W. Bush's and Hillary Clinton's presidential campaigns; the efficacy of various proposed solutions to the failed war on drugs; the poor - quality televised news program for teens (with lots of advertising) that has quietly seeped into many of America's public schools; an early exploration of deceptive practices by the credit card industry; a study of ecosystem destruction in Irian Jaya, one of the world's last substantial rain forests.

We'll also be participating in a variety of activities that will supposedly amp up what Plasticity calls our H.E.R.O. traits: hope, efficacy, resilience and optimism — traits that research suggests are linked with positive outcomes like job satisfaction and organizational commitment.

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

Looking beyond their own corporate needs, Linde is working with a university partner to research the efficacy of this new training technology.

The walled - garden nature of Facebook in particular has come under scrutiny, as they've recently had significant problems regarding the accuracy and efficacy of their advertising methods, with several big brands opting to reduce their ad spend on the site until more accurate metrics are released.

People are less likely to be dissatisfied with market volatility if they feel in control of their financial life, according to a study published last month in the Journal of Behavioral Science, entitled, Market Volatility and Financial Satisfaction: The Role of Financial Self - Efficacy.

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

Other studies, meanwhile, are examining tryp's potential efficacy as an antifungal agent; and as a prognostic indicator in patients with brain cancer (as seen by increased uptake of the amino acid on a PET scan).

Researchers at Israel's Technion Institute of Technology are experimenting with a nanoparticle «barcode» system in order to trace the efficacy of cancer drugs.

It may have to do with Addyi's high pricing (on par with Viagra at $ 26 per pill without an assistance program), its daily intake requirement (unlike Viagra, it adds up to $ 780 per month), its potentially deleterious side effects (low blood pressure and fainting), its restrictions on alcohol consumption (abstinence vs. large quantities not recommended for Viagra patients), a 10 % efficacy rate (whereas Viagra works 50 % of the time compared to a placebo, according to a recent study), and its subtle neurotransmitter - targeting mechanism (contrast that to the obvious hydraulics of Viagra).

Clark credits the poster's unusual design for its efficacy: «The composition of the poster, with the remarkably direct address of the disembodied face, the inescapable eyes, and the pointing finger, highlights this sudden intensification of the bond between the individual and the state.»

Detailed 48 - week results from a Phase 3 study evaluating the efficacy and safety of switching from a regimen containing abacavir, dolutegravir and lamivudine (600 / 50/300 mg)(ABC / DTG / 3TC) to Biktarvy, a once - daily single tablet regimen, in virologically suppressed adults with HIV.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Announced a clinical trial collaboration with Pfizer, Inc. (Pfizer) to evaluate the safety and efficacy of the investigational combination of Yescarta and Pfizer's utomilumab, a fully humanized 4 - 1BB agonist monoclonal antibody, in patients with refractory large B - cell lymphoma.

Once she can start aggregating data from her patients with data from other doctors who are using the app, she will have a huge number of data points that she can use to track everything from the efficacy of the surgery in certain patient populations, to which doctors might get the best outcomes.

«This investigational single tablet regimen brings together the potency of an integrase inhibitor, bictegravir, with the demonstrated efficacy and safety profile of the FTC / TAF backbone,» said Norbert Bischofberger, executive vice president, research and development and chief scientific officer, Gilead Sciences.

But with too many competing flavors, the simplicity and elegance of the dish is lost, and efficacy is diluted.

If I am wrong in either exaggerating the risks of recession or understating the efficacy of policy, the costs of taking out insurance against a recession that can not be met with monetary policy are relatively low.

We do this by conducting clinical trials in which we collect safety and efficacy data about our experimental drugs with the goal of submitting those data to regulatory authorities, like the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), so that these experimental drugs can be approved for use by patients.

We can track the efficacy of transformation with five key indicators: accountability, trust, engagement, agility, and better decision - making.

RxAdvance's staff of experienced pharmacists and care managers provide plan sponsors with clinically - driven services focused on safety, efficacy, and cost containment.

I think the last rate cut also showed that the efficacy of the move was more limited than the BoC let on, with most of the net stimulus (through the FX channel) ultimately a function of the projected path for U.S. monetary policy.

Presentations will highlight the short and long - term effects of Ingrezza on tardive dyskinesia symptoms by body region, long term safety and efficacy data from the KINECT 4 phase 3 open label study and also from RE-KINECT (real - world screening study of patients with possible TD).

John Carreyrou, the Pulitzer Prize - winning reporter who broke the story challenging the efficacy and accuracy of the company's technology last month, now writes that Safeway is looking to dissolve its agreement with Theranos, even though the supermarket chain has already spent $ 350 million to build clinics dedicated to the initiative.

In recognizing the catalysts behind the public's persistence to save and reluctance to spend, additional analysis by policymakers should focus on the efficacy of further rate cuts on spending and investment, as well as potential «roundabout» benefits of a more normal rates regime to affirm support toward the public's saving objectives, with the end goal of boosting public's risk sentiment and perceptions of future economic stability.

With 63 per cent of the executives for the top 10 TSX - traded companies by market capitalization having earned either an MBA or an engineering degree, determining the efficacy of the education tomorrow's business leaders are receiving in sustainability became the goal of this year's survey.

Imagine two scenarios as a potential investor who is entirely unfamiliar with security crowdfunding: (i) encountering different content, of varying quality across each funding portal you visit; (ii) encountering the same content, tested an optimized to ensure the highest quality and efficacy, across all platforms.

This gives me an opportunity to keep a closer eye on developments within my portfolio and likewise to generate greater discussion with readers as I have found this to be one of the most effective ways to increase my own efficacy as a steward of the wealth I have thus far accumulated.

Considering this, coupled with my observation that the number of personal cars has significantly increased since my last visit to Beijing in 2007, I am wary of the efficacy of emission control at the consumer level.

Most biotechs would have shuttered a clinical program that showed absolutely no efficacy whatsoever in a late - stage trial, but Novavax has instead doubled down on RSV by going forth with its phase 3 trial of the RSV F vaccine for infants via maternal immunization, and begun planning for another trial in older adults that's reportedly on track to kick off in 2018.

They have perpetuated myths about the efficacy of condoms, the inability of teenagers to abstain, and the notion that morality has nothing to do with the AIDS epidemic.

He concludes that the reasons for priestsbeing required to give up all conjugal relations with their wives on being ordained was not the «cultural purity of the minister of the altar, but rather the efficacy of mediatory prayer by the sacred minister».

The deprivation not only of life, but of whatever God has given to everyone with life, for its growth and enjoyment, is prohibited by the provision in question, if its efficacy be not frittered away by judicial decision».

You whose loving wisdom fashions my being out of all the forces and all the hazards of earth, teach me to adopt here and now, however clumsily, an attitude the full efficacy of which will be plain to me when I am face to face with the powers of diminishment and death: grant that having desired I may believe, and believe ardently, believe above all things, in your active presence.

(Hebrews 7:26 - 27; 9:14) The Jewish priesthood was a temporary makeshift, bringing oblations which needed constantly to be repeated, (Hebrews 10:3) with no final efficacy in reconciling the soul and God, and so they were the dim foreshadowing of Christ's true priesthood, who has «entered in once for all into the holy place, having obtained eternal redemption.»

When, therefore, we find them also possessing sacraments, fairly magical in their efficacy — especially baptisms, whether of water or of blood, and sacred meals that conferred union with the deity — the query inevitably rises in how far in these regards they influenced Christianity.

Whatever may be the solution of this difficult and perhaps insoluble problem, the evidence of the New Testament is clear that an organized cultus, with accompanying ideas of sacramental efficacy, was already in process of formation before the canon closed.

For it can surely not be seriously denied that, according to Mt 25, a man may encounter Christ in his neighbour more truly and decisively as his Saviour than in a eucharistic communion which, despite the Real Presence and its sacramental efficacy ex opere operate is but the sign and the means of that union with Christ in the Holy Spirit which happens in the difficulties of our daily life even unto our «dying in the Lord».