Sentences with phrase «with electrophysiological»

Serum ferritin levels have been correlated with electrophysiological and cognitive indices in young adults.

Advances in optical imaging and optogenetics combined with electrophysiological recordings enable Albeanu and colleagues to monitor and / or alter patterns of activity at unprecedented synaptic and millisecond resolution, in real time, as animals are engaged in various behaviors.

Electrostatic properties of the side portals and positions of the T1 domain and β subunit are consistent with electrophysiological studies of inactivation gating and with the possibility of K + channel regulation by the β subunit.

Not exact matches

We used mutations with natural and unnatural amino acids, electrophysiological recordings, and x-ray crystallography to identify a charge transfer center in voltage sensors that facilitates this movement.

«We observed no serious side effects in patients treated with dTMS, and it is therefore worth stressing the tolerability of this noninvasive electrophysiological technique,» says Prof. Paul, the study's principal investigator.

Once on the other side, interneurons form a circuit with — and quell the activity of — excitatory neurons in the cortexlike tissue, electrophysiological tests suggest.

Cloning in RNA expression vectors was combined with a sensitive electrophysiological assay in Xenopus oocytes in order to isolate a functional cDNA clone encoding the 5HTlc serotonin receptor.

Nerve conduction studies in motor and sensory nerves of the macaques showed that the Bb infection resulted in specific electrophysiological abnormalities (increased F wave latencies and chronodispersion) that could be prevented with dexamethasone.

Hany Dweck then performed electrophysiological measurements to test all identified compounds with respect to their ability to activate the pheromone - specific neuron.

An electrophysiological assay showed that this complex is oriented with four T1 domains facing the transmembrane pore and four β subunits facing the cytoplasm.

When the axons reaching across the divide were cut with a knife, the interconnectivity between the cortical neurons inside their own compartment was relatively unaffected, whereas the striatal neurons showed no electrophysiological activity.

Indirect evidence, for example, from electrophysiological recordings of the human brain before and after sleep, is consistent with this idea, she says.

Electrophysiological recordings of these cells after culture for about 15 weeks revealed proper responses to currents and to inhibition of receptors needed for normal cerebellar signaling, indicating that function had developed along with structure.

We also conduct electrophysiological, biochemical, imaging, antd behavioral studies with various knockout and transgenic mice to determine how precise genetic manipulations that either activate or abolish specific translational control mechanisms alter synaptic function and behavior.

Her laboratory has successfully combined electrophysiological expertise with molecular and cell biology approaches to better understand complex mechanisms underlying the memory process in mouse models of AD.

Furthermore, simultaneous electrophysiological recording and Ca2 + imaging in hippocampal neurons revealed that the sAHP reduction was associated with a decrease in parallel RyR - mediated Ca2 + transients.

Within these networks in both wakeful rest and sleep states, we found that electrophysiological functional connectivity of both high - frequency broadband (HFB, or high gamma; 70 - 170 Hz) and alpha (8 - 12 Hz) power amplitudes were reproducibly correlated spatially with functional connectivity in separately recorded resting - state fMRI within the same subjects.

A 50 % reduction in HDAC4 restored these and other electrophysiological changes in both the R6 / 2 model, a transgenic over-expresser of Exon 1 HTT with an expanded polyglutamine repeat, and heterozygous Q175 knock - in mice (Q175 + / --RRB-, which carry one normal and one mutant HTT allele with an expanded repeat of ~ 190 polyglutamines, in addition to reversing behavioral alterations in R6 / 2 mice (Mielcarek et al, 2013; PLOS Biology, in press).

Based on evidence from electrophysiological studies showing that both synaptic plasticity and strength of inputs to hippocampal region CA1 vary systematically with ongoing theta oscillations (Hyman et al., 2003; Brankack et al., 1993), it has been suggested that the theta rhythm functions to separate periods of encoding of current sensory stimuli and retrieval of episodic memory cued by current stimuli so as to avoid interference that would occur if encoding and retrieval were simultaneous.

Her research has focused on refining noninvasive electrophysiological approaches for evaluating retinal and anterior visual pathway function in normal subjects and subjects with inherited or acquired diseases that affect visual function.

The Gottfried Laboratory in the Departments of Neurology and Psychology at the University of Pennsylvania is looking to hire a post-doctoral researcher to study the olfactory system using intracranial electrophysiological methods in patients with medically resistant epilepsy.

These developmental perspectives from animal models and electrophysiological studies should be integrated into the fMRI community, which has struggled to reconcile inconsistent findings with regards to functional brain connectivity in ASD over the past several years.

To this aim we have screened our electrophysiological recordings of the magnocellular neurons, previously obtained from acute slices, with an analysis of autocorrelation of action potentials to detect a rhythmic drive as we recently did for organotypic cultures.

Working with motor neurons derived from ALS patients and healthy controls, Dr. Wainger performed fundamental electrophysiological characterization and identified motor neuron hyperexcitability in ALS patient - derived motor neurons (Wainger et al., 2014).

In a series of electrophysiological studies, Zoghbi's team further found that neurons from animals with depleted MECP2 levels have reduced electrical activity due to a smaller number of excitatory synapses, whereas cells from animals carrying an extra copy of the gene have increased electrical activity because of an increase in synapse number.

Fortunately, advances in neuroscience, buttressed since the late 1990s by neuroimaging and brain electrophysiological technology, have led to an emerging consensus about the causes of dyslexia — underlying capacities essential for learning to read, which emerge through brain development, are less developed in children diagnosed with dyslexia.

Two days later a radiofrequency ablation of the electrical circuit was performed at the electrophysiological laboratory directed by Dr. Roberto Santilli of the Veterinary Clinic Malpensa, with an endocardial and epicardial approach with interruption of the arrhythmia.

Oberman's research interest lies in using electrophysiological techniques (such as EEG and TMS and TCS) to investigate neural circuits whose dysfunction may account for the behavioral pathology seen in autism spectrum disorders with the long term goal of developing novel therapeutic interventions.

These biases are reflected in electrophysiological indices (Langeslag & Van Strien, 2009), greater amygdala response for positive stimuli (Mather et al., 2004), and increased fronto - limbic connectivity in older compared with younger adults (St. Jacques, Dolcos, & Cabeza, 2009).