This study will include 36 people with spinal cord injuries who will be treated
with epidural stimulation — a technique in which a device is used to apply electrical current to the spinal cord.
Not exact matches
Edgerton is also working
with various collaborators on NIBIB - funded projects to explore whether
epidural stimulation can be used to help patients
with paralysis of the upper limbs.
Research in animals
with spinal injuries has shown that this type of
epidural stimulation can activate neural circuits in the spinal cord and enable them to use sensory information from the legs to coordinate the muscle contractions necessary for standing and taking a step, Edgerton said at the press conference.
As the first
epidural stimulation participant, Rob Summers moved the needle for the entire field
with his unprecedented recovery.
The initial research hypothesis stated that the two participants
with the American Spinal Injury Association Impairment Scale (AIS) classification of AIS A would not elicit any voluntary movement, despite the therapy intervention, and the two participants who were AIS B would develop voluntary movement following a combination of training and
epidural stimulation.
When coupling the intervention
with rehabilitative therapy, the impact of
epidural stimulation intensified.
To that end, UofL is screening participants for a six - year study that will further explore the life - enhancing effects of
epidural stimulation on people
with spinal cord injury (SCI).
Krassioukov and his colleagues are currently collaborating
with colleagues in the U.S. on a larger trial, examining the benefits of
epidural stimulation on a bigger group.
That study will measure the extent to which
epidural stimulation will improve cardiovascular function as well as facilitate the ability to stand and voluntarily control leg movements below the injury level in 36 participants
with chronic, complete spinal cord injuries.
This work builds on previous research at KSCIRC showing benefits of spinal cord
epidural stimulation, along
with activity - based training, in which individuals
with SCI have achieved voluntary movement, standing and stepping, and improved bladder, bowel and sexual function.
The participants were implanted
with an electrode array for
epidural stimulation, and individual configurations for
stimulation were identified for each participant.
Working
with human research participants, Hirsch and researchers at the Kentucky Spinal Cord injury Research Center (KSCIRC) at UofL, have found that spinal cord
epidural stimulation can safely and effectively elevate blood pressure in individuals
with SCI along
with chronic hypotension.
Working
with human research participants, Hirsch and researchers at the Kentucky Spinal Cord injury Research Center at UofL, have found that spinal cord
epidural stimulation can safely and effectively elevate blood pressure in individuals
with SCI along
with chronic hypotension.
In addition, Kessler is partnering
with the University of Louisville to investigate
epidural stimulation, in which a chip is implanted to deliver an electrical current through the spine to trigger walking.
The technique is called
epidural stimulation and, combined
with physical therapy, produced pioneering results.