Sentences with phrase «with epigenetic research»

Current methods associated with epigenetics research will be discussed, as well as how these technologies are advancing the development of new diagnostics and biomarkers.

Not exact matches

It draws on our extensive interviews with key scientists working at the front - line of microbiome and epigenetic research with the aim of presenting complex science in a way that is easy - to - understand and accessible to all.

It will bring together expert social, biological and medical scientists to take forward thinking and explore the opportunities for promoting co-operation and collaboration between scientists and social scientists in the field of epigenetics The symposium is being organised by the Economic and Social Research Council (ESRC) with support from the Genomics Forum, and the Biotechnology and Biological Sciences Research Council (BBSRC).

«Our study suggests that epigenetic changes to cells treated with cigarette smoke sensitize airway cells to genetic mutations known to cause lung cancers,» says Stephen Baylin, M.D., the Virginia and D.K. Ludwig Professor for Cancer Research and professor of oncology at the Johns Hopkins Kimmel Cancer Center.

Professor Keith Godfrey, from the Medical Research Council Lifecourse Epidemiology Unit and the National Institute for Health Research Southampton Biomedical Research Centre, and a member of the study team, said: «The new findings provide the first direct evidence linking faltering of a baby's growth in the womb with epigenetic modifications that themselves may increase the risk of childhood obesity.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

In collaboration with Prof. Dr. Roland Schüle and his team at the Center of Clinical Research of the Freiburg University Medical Center, the scientists were able to test several epigenetic inhibitors that had been newly developed by Schüle and his team on the cancer stem cell model.

Shen is now researching whether diet has any effect on the epigenetic changes in mice with cancer.

With additional research and knowledge, she said, it may also be possible one day to use these epigenetic changes as markers, which can tell that a child is at risk of obesity and other diseases.

Her research centers on engineering the network of proteins that interact with DNA to control the expression of inherited traits (epigenetics) with the aim of rationally designing new biological systems with predictable, reliable behavior, and replacing «magic bullet medicine» with «smart medicine.»

In order to identify the cancer stem cells from other cells in the tumor, the research team studied epigenetic mechanisms that distinguish between the least - sorted cells, with endless division properties and a potential to create growth, and the more sorted cells which lack this ability.

At ABclonal, we have nearly 100 existing chromatin immunoprecipitation (ChIP)- validated antibodies with a higher specificity than most commercial antibodies, which are used for a wide range of epigenetics studies, from those investigating developmental processes to those researching various diseases.

Joining forces with dermatologists and oncologists from the University Hospital in Zurich and backed by the University Research Priority Program «Translational Cancer Research,» Sommer's team was able to demonstrate that, in melanoma cells, the epigenetic factor EZH2 controls genes that govern tumor growth as well as genes that are important for the formation of metastases.

«Most of the scientific community in Spain is looking with sadness to the current events,» Manel Esteller, director of the Cancer Epigenetics and Biology Program at the Bellvitge Biomedical Research Institute in Barcelona, writes in an e-mail to ScienceInsider.

In this research, the team used Arabidopsis thaliana with mutations in a gene related to DNA methylation, and by confirming the instances of hybrid vigor, they investigated which genes and epigenetic modifications regulating the genes were linked to hybrid vigor.

Further research needs to be done to find out whether this epigenetic signature is just an indicator of breast cancer risk or is involved with the progression of breast cancer.

In this webinar, viewers will gain insight into the current status of epigenetics research, with an emphasis on understanding the mechanism and effects of DNA methylation.

Since HIV infection itself alters epigenetic processes in the immune system, the research team wondered whether a distinct DNA methylation profile, a major epigenetic modification where methyl groups are added to DNA, occurs in those with HIV associated - cognitive impairment and whether it exists in distinct immune cell populations from the blood.

Researchers working at the National Agriculture and Food Research Organization in Japan have found that epigenetic tags, such as methyl groups, on some areas of the plant genome can cause interference with gene editors and reduce their efficiency.

My interests in cardiovascular epigenetics and heart failure pathobiology synergize with the research themes of all three Institutes.

Henk Stunnenberg, leader of one of the research groups that carried out the study and coordinator of both Heroic and the recently started High Impact Project BLUEPRINT, said: «The epigenetic make - up - a layer of regulatory instructions on top of the genome - of the pure embryonic stem cells shows remarkable and unexpected features, in particular with respect to developmental genes.

Uncovering epigenetic variation in plants Dr. Steve Robinson is a Research scientist with AAFC - Saskatoon.

The conference program included sessions on in vitro biology, molecular farming, epigenetics, gene editing, and market acceptance and benefits of biotechnology, with a concluding session on cannabis research.

In particular, our research focuses on developmental origins of health and disease with an emphasis on environmental exposures and epigenetic mechanisms (DNA methylation and noncoding RNA).

Along with other research in this area, Schreiber's HDAC discovery and his novel «signaling network model» of chromatin revealed the genetic complex to be not just a simple structural element, but one with a key regulatory function that is central to epigenetics.

ONE - PARENT SAMPLE SET PARENTAL GUIDANCE RULES: Maternally methylated (red dots) and paternally methylated (blue dots) regions across the human autosomal chromosomes, based on studies of uniparental disomy samplesGENOME RES, 24:554 - 69, 2014 RESEARCHERS Kazuhiko Nakabayashi, Division Chief, Department of Maternal - Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan; David Monk, Principal Investigator, Epigenetics and Cancer Biology Program, Bellvitge Institute for Biomedical Research ORGANISM Human METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker for imprinted genes, though it's possible for patterns of differential methylation to exist in tissues where both alleles are expressed.

«This discovery will advance our understanding of stem cell epigenetics and chromatin structures, provide potential mechanisms on maintaining the hallmark properties of ES cells, and help researchers with the rich source of information to better understand some of the unique features — such as self - renewal and pluripotency — of human embryonic stem cells,» said Ng Huck Hui, Ph.D., senior group leader at GIS and a member of the Singapore team that conducted this research.

Dr. Loftus» current research integrates the identification of these types of epigenetic modifications that mark the melanocyte regulatory genomic landscape with regulatory protein and transcription factor chromatin - binding domains, thus defining groups of non-coding DNA sequences utilized in the control of melanocyte gene expression.

We are seeking to hire a highly - motivated Postdoctoral Fellow with a strong interest in translational bladder cancer research and epigenetics.

Research Focus: I dedicate my time and effort to develop high - throughput sequencing technologies such as single cell transcriptomic, ChIP - Seq, ChIA - PET, and many more... The scientific rational is to understand better and with a different angle, the mechanisms of epigenetic regulation of gene expression in (rare) immune cells, pathologically relevant in many diseases such as asthma, SLE, tuberculosis...

My principal research interest is translational oncology, with a focus on epigenetics.

This Research Team is studying CAR T cell immunotherapy in metastatic pancreatic cancer patients, looking for changes in DNA «on and off switches» (epigenetic changes) following treatment with CAR T.

Concurrently, the research group is examining how the epigenetic profile of different candidate genes predicts, and perhaps changes, in response to recovery from PTSD (and negative self - cognitions) along with its neural correlates.

We also have research interests in cellular regulation by ADP - ribosylation, which links epigenetics to metabolism; lipid kinases; and sphingolipid biosynthesis, which has strong links to both inflammation and cancer, and where mutations in the various proteins involved are associated with a variety of rare diseases.

Landmark research published by City of Hope researchers showed, for the first time, a connection between complex epigenetic mechanisms, blood glucose levels and diabetic complications in patients with metabolic memory.

BETHESDA, MD — An algorithm using epigenetic information from just nine regions of the human genome can predict the sexual orientation of males with up to 70 percent accuracy, according to research presented at the American Society of Human Genetics (ASHG) 2015 Annual Meeting in Baltimore.

In the current study, researchers from Uppsala University in collaboration with research groups around Europe, investigated if coffee and tea consumption may lead to epigenetic changes.

Little research has been performed to understand the specific rules and mechanisms of minimal residual disease, including clonal evolution at the metastatic site, epigenetic programs, interaction with organ defense and immune systems, mechanisms of dormancy and re-awakening, and last but not least, mechanisms of therapy resistance in specific niches.

The Unit studies varied mammalian physiological phenomena from a molecular perspective in the context of the whole organism with a very strong emphasis, following a recent refocusing of our research on Neurobiology and Epigenetics and their interface.

Filed Under: Autoimmune, Food & health, Food Intolerances, Food Research News, GUT Health, Hypertension, Migraine headaches, Pain, Prevention, Toxins & Detoxification Tagged With: digestion, disease prevention, epigenetics, food additives, food allergy, food intolerance, leaky GUT

Rooted in her experience as an elite athlete who used traditional foods to cure her own debilitating injuries, and combining her research with the latest discoveries in the field of epigenetics, Dr. Cate shows how all calories are not created equal; food is information that directs our cellular growth.