Sentences with phrase «with fibrotic»

Rape seed is unsuited to human consumption because it contains a very - long - chain fatty acid called erucic acid, which under some circumstances is associated with fibrotic heart lesions.

These observations do illustrate for the characteristic of AP and chronic pancreatitis like changes exemplified with fibrotic lesions [26].

Not exact matches

Previously Dr. Martini worked at Shire plc in Lexington, Mass., as Senior Director of Discovery Biology and Translational Research, Mass., focusing on fibrotic diseases of muscle, kidney, skin, lung, bone marrow and metabolic liver diseases, with particular emphasis on different therapeutic modalities for pathway modulation.

Research Focus: My research projects are focused on the roles of TNF family members linked to fibrotic disorders associated with scleroderma, atopic dermatitis, idiopathic pulmonary fibrosis and asthma.

In recent years, researchers have developed so - called «senolytic» drugs that wipe out senescent cells in aging mice and mouse models of age - related disease, exploiting the high dependence of these cells on specific biochemical survival pathways.9, 10 In these studies, senolytic drugs have restored exercise capacity9 and formation of new blood and immune precursor cells11 in aging mice to near youthful norms, and prevented or treated mouse models of diseases of aging like osteoarthritis, 12 fibrotic lung disease, 13 hair loss, 14 atherosclerosis, 15,16 and age - related diseases of the heart itself.9 UNITY Biotechnology is leading a growing charge toward the clinic, with human clinical trials expected to begin in 2019.

http://youtu.be/Q2dxSbjgbugAn electrical impulse propagating erratically through a highly fibrotic artificial tissue is made visible with a voltage - sensitive dye.

The cardiomyocytes don't proliferate, but the myofibroblasts keep dividing, gradually replacing healthy tissue with fiber - stiffened (fibrotic) tissue.

Megakaryocytic hyperplasia with abnormal features are characteristic, and it is thought that these cells stimulate and drive fibrotic progression.

High levels of heart disease are associated with selenium - deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China.

One study of Chinese children consuming rapeseed oil indicated an association with Keshan's disease, which causes fibrotic lesions on the heart (2).

Unfortunately, about two - thirds of the mono - unsaturated fatty acids in rapeseed oil are erucic acid, a 22 - carbon monounsaturated fatty acid that had been associated with Keshan's disease, characterized by fibrotic lesions of the heart.

In areas where there is a selenium deficiency, use of rapeseed oil has been associated with a high incidence of fibrotic lesions of the heart, called Keshan's disease.20 The animal studies carried out over the past twenty years suggest that when rapeseed oil is used in impoverished human diets, without adequately saturated fats from ghee, coconut oil or lard, then the deleterious effects are magnified.

FLO a Golden Retriever, female, one and a half year old with a severe pulmonary stenosis withhypoplastic wide fibrotic subvalvular component.