Sentences with phrase «with filopodia»
In particular, HD mutations impacting the RhoGTPase signaling pathway interfered with filopodia, the slender projections that cells use to direct movement and communicate with other cells.
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Michael's image shows COS - 7 cells ectopically expressing the Fcγ - receptor performing phagocytosis on beads opsonised with Immunoglobulin G. His false - colour scanning electron micrograph shows filopodia and pseudopodia projecting around the beads, which will subsequently be fully engulfed.
RNA interference of fascin reduced the number of filopodia, and remaining filopodia had abnormal morphology with wavy and loosely bundled actin organization.
Fluorescence recovery after photobleaching of GFP - tagged wild - type and S39A fascin showed that dephosphorylated fascin underwent rapid cycles of association to and dissociation from actin filaments in filopodia, with t (1/2) < 10 s.