Sentences with phrase «with gene duplication»

According to the textbooks, the process by which new genes form starts with gene duplication.

Not sure what you mean by «genetic information», but evolution requires changes in the genes of the next generation of organism, which is exactly what happens with gene duplication, transposition, etc..

Not exact matches

In this cycle, new gene copies often arise by gene duplication, with the copies persisting or adapting into new roles within the genome for varying lengths of time, or dying off and being lost randomly.

So what this shows is it sort of gives us a window to say, well, one way the gene duplication allows novelty or specialization or adaptation is by having more genetic parts to work with — each part can be optimized and specialized in a way that if you just have one part, you can do.

«The evolution of the fan coincides with the duplication of that gene,» Khila said, also noting that the expression of the gene in the tip of the leg is significant.

Researchers checked the genomes of 150 patients with schizophrenia and those of 268 healthy people, looking for large duplications and deletions of genetic material that disrupted the function of a gene.

Pairwise alignments were calculated using Shuffle - LAGAN (window size, 400 bp; step size 40 bp; translated anchoring), a glocal alignment algorithm that is able to calculate optimal alignments by using both local alignments and global maps of sequence rearrangements (e.g. duplications of the fiber gene in adenovirus genomes with 2 fibers)[57].

Although none of the German Neolithic samples carries the copy number expansion of the AMY2B gene associated with starch digestion, we find that this gene is present in three copies in NGD, though this is due to a large segmental duplication that is shared with multiple modern dogs, an event separate from the tandem AMY2B duplications.

To avoid any duplication within the IMPC, a gene already reserved by another center (i.e. already produced, or with production underway, or planned to be produced) will not be selected but the production state will be transferred to the requestor.

Compared with the ancestral lineage, the East African cichlid genomes possess: an excess of gene duplications; alterations in regulatory, non-protein-coding elements in the genome; accelerated evolution of protein - coding elements, especially in genes for pigmentation; and other distinct features that affect gene expression, such as insertions of transposable elements and regulation by novel microRNAs.

Many individual ASD patients had deletions or duplications of multiple genes within this network, but for those patients with just a single gene from the network changed, that single gene appeared to play an important role.

We found an excess of gene duplications in the East African lineage compared to tilapia and other teleosts, an abundance of non-coding element divergence, accelerated coding sequence evolution, expression divergence associated with transposable element insertions, and regulation by novel microRNAs.

We found that an unusually high number of genes affected by these DNA deletions / duplications are associated with the functioning of synaptic transmission between nerve cells.

With no tell - tale signs of whole genome duplication, the researchers say, the octopus must have instead duplicated specific regions of its genetic code — and acquired totally novel genes — over the course of its evolution.

The evolution of mammalian genomes is thought to include at least two whole genome duplications of an ancestral genome (Holland et al., 1994), as well as duplication of sub-chromosomal segments together with extensive gene duplication that has given rise to many large multigene families (Lundin, 1993).

In concordance with these results, MECP2 gene duplications have been reported in both men and women that suffer from autism - spectrum disorders.

MANDs share similar clinical phenotypes and are reported to be caused by deletions, duplications, or pathogenic variants of MBD5, a gene that has been implicated in Autism Spectrum Disorder (ASD) and shares pathways with other ASD - associated genes.

The gene variant for white colour in pigs differs from the gene variant found in wild boar, with at least five different mutations, four of which are duplications of DNA sequences.