Tissue engineering combined
with gene therapy technology has the potential to manage the repair of defective articular cartilage.
Not exact matches
Editas, a startup based in Cambridge and founded in November 2013, wants to eventually use the
technology to treat disease by coming up
with therapies that can modify faulty disease - causing
genes.
However, in the wake of fatalities from
gene therapy and other
technologies, as well as the potential for cancers associated
with stem cell transplants, governments are understandably nervous about safety issues — not to mention the ethical maze of tinkering
with fledgling life.
The roadmap outlines future research directions toward the goal of enhancing human radioresistance, including upregulation of endogenous repair and radioprotective mechanisms, possible leeways into
gene therapy in order to enhance radioresistance via the translation of exogenous and engineered DNA repair and radioprotective mechanisms, the substitution of organic molecules
with fortified isoforms, the coordination of regenerative and ablative
technologies, and methods of slowing metabolic activity while preserving cognitive function.
«It's as close to a definitive clinical success
with gene therapy as one could have at this point in the development of the
technology,» says genetic engineer Richard Mulligan of Harvard University.
To enable scaling long term, we have entered into an agreement
with Cell
Therapy Catapult Services, a research organization specializing in the development of technologies which speed the growth of the cell and gene therapy in
Therapy Catapult Services, a research organization specializing in the development of
technologies which speed the growth of the cell and
gene therapy in
therapy industry.
It was created to support development and commercialization of regenerative medicines and associated enabling
technologies,
with a specific focus on cell and
gene therapy.
With her recent groundbreaking findings in the field of RNA - mediated regulation based on the CRISPR - Cas9 system, E. Charpentier has laid the foundation for the development of a novel, highly versatile and specific genome editing
technology that is revolutionizing life sciences research and could open up whole new opportunities in biomedical
gene therapies.
In collaboration
with the University of Massachusetts Medical School (UMMS) and Auburn University (AU), Lysogene is developing IND - supporting preclinical studies using AAV
gene therapy technology to translate the initial proof of concept into a viable drug development program to the benefit of patients in urgent need.
Her postdoctoral research was conducted
with a team of CNRS researchers in Paris, France, where she employed biochemical and
gene therapy technologies to investigate the impact of protein aggregation in Parkinson's disease.
This is an issue that can be dealt
with and we have the
technology to do that in the form of
gene therapy,» says senior author Dr. Ronald G. Crystal, chief of the Division of Pulmonary and Critical Care Medicine at NewYork - Presbyterian Hospital / Weill Cornell Medical Center, and the Bruce Webster Professor of Internal Medicine and Professor of Genetic Medicine at Weill Cornell Medical College.
The 1990s saw extreme advances in
technology,
with the World Wide Web, the first
gene therapy trial, and the first designer babies [8] all emerging in 1990 and being improved and built upon throughout the decade.