Sentences with phrase «with glia»

Watkins» work with glia, for example, has indicated that long - term opioid therapy may have an effect similar to that of chronic inflammation, causing glial cells to release an excess of cytokines that actually reduce the drug's effectiveness in blocking pain.

With the Glia template, the stethoscope can be made in less than three hours and costs less than $ 3 to produce.

They found 118 genes that were on when they should have been off or off when they should have been on, compared with glia from healthy people.

Not exact matches

To trace the source of the problem, the scientists analyzed what genes in the glia from people with schizophrenia were turned on and off.

Although the prevailing idea has been that the devastating disease, which strikes some 1 percent of U.S. adults, is primarily caused by something going wrong with neurons, the scientists suspected the brain's support cells, called glia.

Glia - making cells from people with schizophrenia also mostly failed to turned into astrocytes, which help neurons connect and determine when those connections, or synapses, fire.

But when the immune system becomes activated in response to an illness or injury, glia in regions associated with pain processing seem to take on another role: They release inflammatory molecules that interact with nearby neurons to amplify pain signals.

The mental sensations of self, desire, fear, love and hate seem better understood in the light of Fields's discoveries about the manner in which glia interact with neural synapses and interact with one another.

A study in the International Society for Stem Cell Research's journal Stem Cell Reports, published by Cell Press on November 20 shows that a Sox2 protein, alone or in combination with another protein, Ascl1, can cause nonneuronal cells, called NG2 glia, to turn into neurons in the injured cerebral cortex of adult mice.

Mouse brain nerve cells (green) making a disease - causing version of the tau protein were grown in lab dishes with supporting brain cells called glia.

They found that when microglia were also lost, Müller glia showed almost no regenerative activity after three days of recovery, compared with approximately 75 percent regeneration in the control population.

To conduct the study, scientists took dental pulp cells from donated baby teeth of three children with diagnoses of non-syndromic autism (part of the on - going «Tooth Fairy Project») and reprogrammed the cells to become either neurons or astrocytes, a type of glia or support cell abundantly found in the brain.

Understanding the coordinated development of motor neurons and glia may inform ways to prod stem cells into generating more glia after someone suffers an injury with nerve damage.

Going forward, Dr. Mann hopes to explore how the glia coordinate with each other without the benefit of hardwiring like motor neurons; perhaps they communicate with each other, or with the motor neurons.

With PAR3 out of the picture, neural stem cells and progenitors are free to differentiate into new neurons and glia.

Glia do everything from holding neurons in place to supplying them with nutrients and oxygen to protecting them from pathogens.

The layering within these columns was indistinguishable from the adjacent, control retina and contained cells with the appropriate morphology for their nuclear layer (rods and cones in the ONL, bipolar, amacrine, horizontal, and Müller glia in the INL, and RGCs in the GCL).

Ivan R. Minev, Pouria Moshayedi, James W. Fawcett, and Stéphanie P. Lacour Interaction of Glia with a Compliant, Microstructured Silicone Surface Acta Biomaterialia, no. 6: 6936 — 42 (2013)

Towards our goals we study retinal cells throughout their life, from embryonic stem cells to retinal progenitors to differentiating and mature neurons and glia — with one eye on neuronal regeneration (meaning de-novo neurogenesis) in the mammalian retina — and with another eye on retinal disease pathomechanisms.

[19] In the current study, [15] PDGF - AS mice exhibited an increased number and intensity of areas staining for reactive microglia (using Iba1) and astroglia (using GFAP), but vaccination with AFF 1 prevented nearly all of this disease - associated excess, with treated animals exhibiting only the burden of reactive glia present in similar - aged WT mice.